PrescriptionGiant is a FREE prescription savings program that can save you up to 75% on your prescriptions with or without insurance!

Zyrtec-D (Generic Pseudoephedrine)

Actual product appearance may differ slightly.

Click the CARD below to print or take a screenshot on your mobile phone or tablet. There is no need to download another app!

If you would like to personalize your card enter your full name in the member name field below the card at this link and click the Update button.


Why is this medication prescribed?

Zyrtec-D is a combination medication that contains two active ingredients: cetirizine and pseudoephedrine. It is commonly prescribed to relieve symptoms associated with seasonal allergies and nasal congestion. Here’s a breakdown of the components:

  • Cetirizine: This is an antihistamine that helps alleviate symptoms such as sneezing, itching, watery eyes, and runny nose. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms.
  • Pseudoephedrine: This is a decongestant that works by narrowing blood vessels in the nasal passages. This reduces swelling and congestion, making it easier to breathe.

How should this medicine be used?

Zyrtec-D is a combination medication containing cetirizine (an antihistamine) and pseudoephedrine (a decongestant). It is commonly used to relieve symptoms associated with allergies and nasal congestion. Here are general guidelines on how Zyrtec-D should be used:

  • Dosage: Follow your healthcare provider’s instructions regarding the dosage. The recommended dosage may vary based on the severity of your symptoms and your overall health. The typical adult dosage is usually one tablet every 12 hours.
  • Administration: Zyrtec-D is taken orally with a full glass of water. It can be taken with or without food.
  • Swallow Whole: Do not crush or chew the tablet. Swallow it whole to ensure proper and controlled release of the medication.
  • Stay Hydrated: Drink plenty of fluids to stay well-hydrated, especially if you experience dry mouth as a side effect.
  • Timing: Take the medication at the same times each day to maintain a consistent level of the drug in your bloodstream.
  • Duration of Use: Use Zyrtec-D for the duration prescribed by your healthcare provider, even if your symptoms improve before the medication is finished.
  • Avoid Overuse: Prolonged or excessive use of decongestants like pseudoephedrine can lead to dependence or rebound congestion. Use Zyrtec-D as directed by your healthcare provider.
  • Medical Supervision: Use Zyrtec-D under the supervision of your healthcare provider, especially if you have pre-existing medical conditions or are taking other medications.

Remember to read and follow the instructions provided on the medication label, and do not self-adjust the dosage without consulting your healthcare provider. If you have any questions or concerns about how to use Zyrtec-D, seek guidance from your healthcare professional or pharmacist.

Other uses for this medicine

Zyrtec-D is primarily used to relieve symptoms associated with allergies and nasal congestion. It’s commonly prescribed for conditions like hay fever or respiratory allergies. Its combination of cetirizine (antihistamine) and pseudoephedrine (decongestant) makes it effective for managing both allergy symptoms and nasal congestion.

What special precautions should I follow?

Special Precautions for Zyrtec-D:

  • Medical History: Before taking Zyrtec-D, inform your healthcare provider about your complete medical history, especially if you have conditions such as high blood pressure, heart problems, diabetes, kidney disease, or glaucoma.
  • Allergies: If you are allergic to cetirizine, pseudoephedrine, or other antihistamines/decongestants, let your healthcare provider know.
  • Pregnancy and Breastfeeding: Consult your healthcare provider if you are pregnant or breastfeeding before using Zyrtec-D, as some components may pass into breast milk or have potential effects on the developing fetus.
  • Interaction with Other Medications: Zyrtec-D may interact with other medications, including monoamine oxidase inhibitors (MAOIs), certain antidepressants, and other medications that may increase blood pressure. Inform your healthcare provider about all medications you are currently taking.
  • Medical Procedures: If you are scheduled for surgery or dental work, inform your healthcare provider that you are taking Zyrtec-D, as it may interact with certain anesthetics.
  • Limiting Caffeine Intake: Zyrtec-D contains pseudoephedrine, which can cause nervousness or insomnia. Limiting caffeine intake can help reduce these effects.
  • Avoid Alcohol: Combining alcohol with Zyrtec-D can increase the risk of side effects such as drowsiness and dizziness. It’s advisable to limit or avoid alcohol consumption while taking this medication.
  • Driving and Operating Machinery: Zyrtec-D may cause drowsiness or dizziness. Be cautious when driving or operating machinery until you know how the medication affects you.

Always follow your healthcare provider’s advice and the instructions on the medication label. If you have any concerns or experience unusual side effects, contact your healthcare provider promptly. Do not self-adjust the dosage or use Zyrtec-D without medical guidance.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Zyrtec-D. However, taking the medication with or without food is generally acceptable. If you have any concerns about potential interactions with specific foods or dietary habits, it’s recommended to discuss this with your healthcare provider.

What should I do if I forget a dose?

If you miss a dose of Zyrtec-D:

  • Take it as soon as you remember. If it’s close to the time of your next scheduled dose, skip the missed dose.
  • Do not double up on doses. Taking more than the prescribed amount can lead to an increased risk of side effects without providing additional benefits.
  • Resume your regular dosing schedule. Continue taking the medication as prescribed by your healthcare provider.

If you have questions or concerns about missed doses, it’s advisable to contact your healthcare provider for guidance. They can provide personalized advice based on your specific situation.

What side effects can this medication cause?

Zyrtec-D, like any medication, can cause side effects. It’s important to be aware of potential side effects and to promptly report any unusual or severe symptoms to your healthcare provider. Common side effects of Zyrtec-D include:

  • Dry Mouth: This is a common side effect of antihistamines like cetirizine.
  • Insomnia: Pseudoephedrine, a component of Zyrtec-D, can cause stimulation and difficulty sleeping in some individuals. It’s often recommended to avoid taking Zyrtec-D close to bedtime.
  • Drowsiness: While cetirizine is considered a non-sedating antihistamine, some individuals may still experience mild drowsiness. This effect is generally less than that seen with older antihistamines.
  • Dizziness: Pseudoephedrine can cause dizziness or lightheadedness in some people.
  • Nervousness or Restlessness: Pseudoephedrine is a stimulant and may cause increased alertness or restlessness in some individuals.
  • Increased Heart Rate (Tachycardia): Pseudoephedrine can stimulate the heart and lead to an increased heart rate.
  • Increased Blood Pressure: Pseudoephedrine can elevate blood pressure, and it should be used with caution in individuals with hypertension.
  • Gastrointestinal Upset: Some individuals may experience stomach discomfort, nausea, or vomiting.
  • Headache: Headaches are a possible side effect.
  • Difficulty Urinating: Pseudoephedrine can cause urinary retention in some individuals.

It’s important to note that serious side effects are rare, but they can occur. Seek medical attention immediately if you experience any severe reactions, such as:

  • Severe allergic reactions (e.g., rash, itching, swelling, severe dizziness, difficulty breathing)
  • Fast or irregular heartbeat
  • Tremors or shaking
  • Difficulty sleeping or changes in sleep patterns

This is not an exhaustive list of side effects, and individuals may react differently to the medication. Always follow your healthcare provider’s instructions, and inform them of any pre-existing medical conditions or medications you are taking to help minimize the risk of adverse effects.

What should I know about storage and disposal of this medication?

Storage and Disposal of Zyrtec-D:

  • Storage:
    • Store Zyrtec-D at room temperature away from light and moisture.
    • Keep the medication out of reach of children.
    • Do not store it in the bathroom, as the humidity may affect the stability of the medication.
  • Disposal:
    • Dispose of Zyrtec-D in accordance with local regulations or guidelines.
    • Do not flush medications down the toilet or pour them into a drain unless instructed to do so.
    • If in doubt about how to dispose of unused or expired medication, consult with a pharmacist or your local waste disposal facility.

In case of emergency/overdose

If you suspect an overdose or experience severe symptoms, seek emergency medical attention immediately. Symptoms of an overdose may include:

  • Restlessness
  • Rapid or irregular heartbeat
  • Hallucinations
  • Seizures
  • Severe dizziness or fainting
  • Difficulty breathing

What other information should I know?

  • Allergic Reactions: If you experience signs of an allergic reaction, such as rash, itching, swelling, severe dizziness, or difficulty breathing, seek immediate medical attention.
  • Medical Check-ups: Regularly check in with your healthcare provider to monitor the effectiveness of the medication and discuss any concerns or changes in your health.
  • Interactions: Inform your healthcare provider about all medications, including over-the-counter drugs and herbal supplements, that you are taking to avoid potential interactions.
  • Avoiding Driving or Hazardous Activities: Due to the potential for drowsiness or dizziness, be cautious when driving or operating machinery until you know how Zyrtec-D affects you.
  • Alcohol and Other CNS Depressants: Limit or avoid alcohol consumption while taking Zyrtec-D, as it may enhance the sedative effects of the medication.
  • Prolonged Use: Prolonged use of decongestants like pseudoephedrine can lead to rebound congestion. Use Zyrtec-D as directed by your healthcare provider.
  • Non-prescription Use: Do not use Zyrtec-D for conditions for which it was not prescribed, and do not exceed the recommended dosage.

Always follow the specific instructions provided by your healthcare provider and on the medication label. If you have questions or concerns about your medication, consult your healthcare provider or pharmacist for guidance.

Copyright © 2023 PrescriptionGiant.com