PrescriptionGiant is a FREE prescription savings program that can save you up to 75% on your prescriptions with or without insurance!

Zeposia (Generic Ozanimod)

Actual product appearance may differ slightly.

Click the CARD below to print or take a screenshot on your mobile phone or tablet. There is no need to download another app!

If you would like to personalize your card enter your full name in the member name field below the card at this link and click the Update button.

Why is this medication prescribed?

Zeposia (ozanimod) is prescribed for the treatment of relapsing forms of multiple sclerosis (MS). Multiple sclerosis is a chronic autoimmune condition that affects the central nervous system, leading to inflammation, damage to the protective covering of nerve fibers, and disruption of communication between the brain and the rest of the body.

Zeposia is classified as a sphingosine 1-phosphate (S1P) receptor modulator. It works by modulating the immune system, specifically by preventing certain white blood cells (lymphocytes) from entering the central nervous system. This action helps reduce inflammation, nerve damage, and the frequency of relapses in individuals with relapsing forms of MS.

The specific forms of relapsing MS that Zeposia is indicated for include relapsing-remitting MS (RRMS), active secondary progressive MS (SPMS), and clinically isolated syndrome (CIS). It’s important to note that Zeposia is not a cure for MS, but it is used to help manage the symptoms and reduce the frequency of relapses.

How should this medicine be used?

As for how Zeposia is used, the specific instructions may vary, and it’s important to follow the guidance provided by the prescribing healthcare provider. Generally, Zeposia is taken orally as a capsule. Here are some general guidelines:

  • Starting Dose: There is often an initial dose escalation period to reduce the risk of side effects. During this period, the dosage may be gradually increased.
  • Maintenance Dose: After the initial period, a maintenance dose is typically established. This is the ongoing dose that helps manage the condition.
  • Regular Monitoring: Patients using Zeposia may be monitored regularly for potential side effects and to assess the medication’s effectiveness.
  • Compliance: It’s crucial to take Zeposia exactly as prescribed by the healthcare provider. Missing doses or stopping the medication abruptly can affect its effectiveness.
  • Side Effects: Like any medication, Zeposia may cause side effects, and individuals should be aware of potential reactions. Common side effects may include headaches, high blood pressure, liver enzyme elevations, and respiratory infections. However, not everyone will experience these side effects.
  • Precautions: Before starting Zeposia, individuals should inform their healthcare provider about their medical history, existing health conditions, and any other medications they are taking. Certain pre-existing conditions may require careful consideration before using this medication.

It’s essential to consult with a healthcare professional for personalized advice and to stay informed about any updates or changes in the prescribing information for Zeposia. If you or someone you know has been prescribed Zeposia, follow the healthcare provider’s instructions and contact them with any questions or concerns.

Other uses for this medicine

The primary approved use for Zeposia (ozanimod) was in the treatment of relapsing forms of multiple sclerosis (MS). It’s crucial to note that using medications off-label (for purposes not approved by regulatory authorities) should only be done under the guidance of a healthcare professional. Always consult with a doctor for the most up-to-date and accurate information regarding medications.

What special precautions should I follow?

Regarding special precautions for Zeposia, here are some general considerations:

  • Liver Function Monitoring: Zeposia can affect liver function, so regular monitoring of liver enzymes is typically recommended. Healthcare providers may perform liver function tests before initiating treatment and during the course of therapy.
  • Cardiac Monitoring: Zeposia may cause a temporary decrease in heart rate when first taken. Therefore, patients are often monitored for at least six hours after the first dose. People with certain pre-existing cardiac conditions may need more extensive monitoring.
  • Blood Pressure Monitoring: Zeposia may increase blood pressure. Blood pressure should be monitored regularly, and adjustments to antihypertensive medications may be necessary.
  • Infections: Zeposia may increase the risk of infections. Before starting treatment, individuals may be screened for certain infections, and healthcare providers will monitor for signs of infections during treatment.
  • Vaccinations: Certain vaccinations may be recommended before starting Zeposia, as it’s important to be up-to-date on immunizations to help prevent infections.
  • Contraindications: Zeposia may be contraindicated in individuals with certain pre-existing conditions. Inform your healthcare provider about your complete medical history, including any cardiovascular, liver, or respiratory conditions.
  • Pregnancy and Breastfeeding: The safety of Zeposia during pregnancy and breastfeeding is not well established. It’s essential for individuals who are pregnant, planning to become pregnant, or breastfeeding to discuss the potential risks and benefits of Zeposia with their healthcare provider.
  • Other Medications: Inform your healthcare provider about all the medications you are currently taking, including prescription, over-the-counter, and herbal supplements. Some medications may interact with Zeposia.

Remember, these are general considerations, and individual circumstances may vary. Always follow your healthcare provider’s instructions and attend regular check-ups to monitor for any potential side effects or complications. If you have specific concerns or questions about Zeposia, it’s best to discuss them with your healthcare provider.

What special dietary instructions should I follow?

There were no specific dietary restrictions associated with Zeposia. However, it’s essential to follow any dietary recommendations or restrictions provided by your healthcare provider.

What should I do if I forget a dose?

If you forget to take a dose of Zeposia, follow these general guidelines:

  • As Soon As Possible: Take the missed dose as soon as you remember on the same day.
  • Next Dose: If it’s almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
  • Double Dose: Do not take a double dose to make up for a missed one.
  • Consult Your Healthcare Provider: If you are unsure about what to do or if you have missed multiple doses, contact your healthcare provider for guidance.

What side effects can this medication cause?

Zeposia (ozanimod) can cause various side effects, and it’s important to be aware of them. It’s crucial to note that not everyone will experience these side effects, and some individuals may experience side effects not listed here. Always consult with your healthcare provider for personalized information and advice. Common side effects of Zeposia may include:

  • Headache: Headaches are a common side effect, especially during the initial period of treatment.
  • High Blood Pressure: Zeposia may lead to an increase in blood pressure. Regular monitoring of blood pressure is usually recommended.
  • Elevated Liver Enzymes: Zeposia can affect liver function, leading to elevated liver enzymes. Regular liver function tests may be conducted to monitor for this.
  • Respiratory Infections: Zeposia may increase the risk of respiratory infections, such as upper respiratory tract infections.
  • Liver Function Abnormalities: In addition to elevated liver enzymes, more severe liver problems, including liver injury, have been reported in some cases.
  • Bradyarrhythmia and Atrioventricular Block: Zeposia may cause a temporary decrease in heart rate (bradycardia) and atrioventricular block. Cardiac monitoring may be conducted, especially after the first dose.
  • Macular Edema: Zeposia has been associated with macular edema, which is swelling of the central part of the retina. Individuals may experience vision changes.
  • Infections: Zeposia may increase the risk of infections, including serious infections. Individuals may be more susceptible to certain types of infections, and it’s important to monitor for signs of infection.
  • Skin Cancer: There have been reports of an increased risk of skin cancer, including basal cell carcinoma and melanoma.
  • Hypersensitivity Reactions: Some individuals may experience allergic reactions, including rash, itching, and swelling.

It’s crucial to report any new or worsening symptoms to your healthcare provider promptly. Additionally, if you experience severe or persistent side effects, contact your healthcare provider for guidance. This list is not exhaustive, and there may be other side effects associated with Zeposia. Always follow your healthcare provider’s advice and attend regular check-ups to monitor for any potential complications.

What should I know about storage and disposal of this medication?

Storage and Disposal of Zeposia:

  • Storage: Follow the storage instructions provided by the pharmacist or healthcare provider. Typically, Zeposia should be stored at room temperature, away from light and moisture. Keep it in its original packaging.
  • Keep Out of Reach of Children: Ensure that Zeposia is stored in a location that is inaccessible to children and pets.
  • Avoid Extreme Conditions: Do not expose Zeposia to extreme temperatures (very hot or very cold), as this may affect its stability and efficacy.
  • Do Not Use Expired Medication: Check the expiration date on the packaging, and do not use Zeposia if it has expired.
  • Disposal: Dispose of unused or expired medications in accordance with local regulations. Do not flush medications down the toilet unless specifically instructed to do so.

In case of emergency/overdose

In the event of an emergency or suspected overdose, contact emergency services or your local poison control center immediately. Signs of an overdose or adverse reaction may include severe dizziness, fainting, slow or irregular heartbeat, difficulty breathing, or other serious symptoms.

What other information should I know

  • Regular Monitoring: Zeposia may require regular monitoring through blood tests and other assessments to check for potential side effects and ensure the medication’s effectiveness.
  • Follow-up Appointments: Attend all scheduled follow-up appointments with your healthcare provider to monitor your response to treatment and address any concerns.
  • Inform Healthcare Providers: Inform all healthcare providers involved in your care, including dentists and surgeons, about your use of Zeposia. They need to be aware of all the medications you are taking.
  • Pregnancy and Contraception: If you are pregnant, planning to become pregnant, or breastfeeding, discuss this with your healthcare provider. Adequate contraception may be advised during treatment.
  • Patient Assistance Programs: If cost is a concern, inquire about patient assistance programs that may help with the affordability of Zeposia.
  • Avoid Alcohol: Consult with your healthcare provider regarding alcohol consumption while taking Zeposia, as alcohol may interact with the medication.
  • Travel Precautions: Inform your healthcare provider if you plan to travel, especially to areas with a high risk of certain infections. They may provide recommendations for vaccinations or other precautions.

Always follow your healthcare provider’s instructions and communicate openly about any concerns or changes in your health. This information is a general guide, and specific details may vary based on individual circumstances and the most recent medical guidelines.

Copyright © 2023