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Zentrip (Generic Meclizine)

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Why is this medication prescribed?

Meclizine is a medication commonly prescribed to treat symptoms of motion sickness and vertigo. It is an antihistamine that works by reducing the effects of histamine, a natural substance in the body that can cause symptoms like nausea, vomiting, and dizziness.

How should this medicine be used?

The usage of meclizine depends on the specific condition being treated, and it’s essential to follow the guidance provided by your healthcare provider or the instructions on the medication label. Here are some general guidelines for using meclizine:

  • Motion Sickness Prevention: For adults and children 12 years and older, the typical dose is usually 25 to 50 milligrams (mg) taken one hour before travel. For children between 6 and 12 years old, the dose is usually 12.5 to 25 mg taken one hour before travel. Follow any repeat dosing instructions if needed during extended travel.
  • Vertigo and Dizziness Treatment: The dosage for the treatment of vertigo or dizziness may vary depending on the severity of your symptoms and your healthcare provider’s recommendations. In many cases, a typical adult dose is 25 mg to 100 mg per day, divided into multiple doses. Follow your doctor’s guidance on the duration of treatment.
  • Chewable Tablets: If you are using chewable meclizine tablets, make sure to chew them thoroughly before swallowing.
  • Other Uses: Meclizine may be used off-label in some cases, as determined by your healthcare provider. These off-label uses might include nausea and vomiting associated with other medical conditions.

It’s essential to use meclizine as directed and consult with a healthcare professional if you have any questions or concerns about its use, especially if you have underlying medical conditions or are taking other medications. Additionally, meclizine should not be used as a long-term solution without a healthcare provider’s supervision.

Other uses for this medicine

While Meclizine is primarily used for motion sickness and vertigo, it may sometimes be prescribed for other conditions at a doctor’s discretion. These off-label uses might include:

  • Treatment of nausea and vomiting caused by other medical conditions or medications.
  • Management of dizziness and balance problems associated with certain medical conditions.
  • Adjunctive therapy in the treatment of migraine headaches.

What special precautions should I follow?

Special precautions and considerations when using Meclizine:

  • Allergies: Inform your healthcare provider if you are allergic to Meclizine or any other medications.
  • Pregnancy and Breastfeeding: It’s essential to discuss the use of Meclizine with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding, as the safety of Meclizine during pregnancy and lactation is not well established.
  • Medical Conditions: Let your healthcare provider know about any underlying medical conditions you have, especially if you have asthma, glaucoma, an enlarged prostate, or difficulty urinating, as Meclizine may worsen these conditions.
  • Other Medications: Inform your healthcare provider about all the prescription and over-the-counter medications, vitamins, and supplements you are taking, as Meclizine may interact with certain drugs. Specifically, it may enhance the sedative effects of alcohol and other central nervous system depressants.
  • Drowsiness: Meclizine can cause drowsiness, so use caution when operating heavy machinery or engaging in activities that require alertness until you know how the medication affects you.
  • Alcohol: Avoid alcohol while taking Meclizine, as it can intensify the drowsiness and dizziness associated with the medication.
  • Overdose: In case of an overdose, seek immediate medical attention or contact a poison control center. Overdose symptoms may include extreme drowsiness, seizures, or irregular heartbeat.

Always follow your healthcare provider’s instructions regarding the use of Meclizine and ask any questions or express concerns you may have about its use. It’s important to use this medication as directed and not to exceed the recommended dosage unless instructed by your healthcare provider.

What special dietary instructions should I follow?

Meclizine is typically taken with or without food, and there are no specific dietary restrictions associated with its use. You can take it with a meal if it helps reduce stomach upset, but it’s not necessary. However, to avoid potential drowsiness associated with Meclizine, it’s advisable to avoid alcohol and limit your intake of other substances that can cause drowsiness, such as certain cold or allergy medications, while you’re taking Meclizine.

What should I do if I forget a dose?

If you forget to take a dose of Meclizine, here’s what you should do:

  • If it’s close to the time for your next dose: Take the missed dose as soon as you remember. However, if it’s almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.
  • If you’re unsure or have questions: If you’re unsure about what to do or have any concerns about missing a dose, it’s essential to contact your healthcare provider or pharmacist for guidance. They can provide specific advice based on your situation and the treatment plan they’ve prescribed.

What side effects can this medication cause?

Meclizine, like any medication, can cause side effects. Not everyone will experience these side effects, and some people may experience them to a greater degree than others. Common side effects of Meclizine can include:

  • Drowsiness: This is one of the most common side effects of Meclizine. It can impair your ability to drive or operate machinery, so you should avoid such activities until you know how the medication affects you.
  • Dry Mouth: Some people may experience a dry or parched feeling in the mouth while taking Meclizine. Staying hydrated and using sugar-free gum or candy may help relieve this symptom.
  • Blurred Vision: Meclizine can sometimes cause blurred vision or difficulty focusing. This can be more pronounced if you have certain eye conditions.
  • Constipation: Constipation can occur in some individuals while taking Meclizine. Increasing your fluid intake and dietary fiber may help alleviate this side effect.
  • Dizziness: While Meclizine is often used to relieve dizziness, it can paradoxically cause dizziness or unsteadiness in some people, especially when getting up quickly from a sitting or lying position.
  • Headache: Headaches are a less common side effect but can occur in some individuals.
  • Nausea and Upset Stomach: Ironically, Meclizine, which is used to treat nausea, can occasionally cause mild nausea or stomach upset as a side effect.
  • Fatigue: Some individuals may experience fatigue or a feeling of tiredness while taking Meclizine.
  • Allergic Reactions: While rare, severe allergic reactions to Meclizine can occur. Seek immediate medical attention if you experience symptoms such as hives, itching, swelling of the face or throat, severe dizziness, or difficulty breathing.
  • Other Side Effects: There are other potential side effects that are less common but can still occur. If you experience any unusual or severe side effects while taking Meclizine, it’s important to contact your healthcare provider.

It’s important to note that this list is not exhaustive, and individual reactions to Meclizine can vary. If you have concerns about the side effects of Meclizine or are experiencing any adverse effects while taking it, it’s essential to discuss these concerns with your healthcare provider. They can provide guidance and, if necessary, adjust your treatment plan or recommend an alternative medication.

What should I know about storage and disposal of this medication?

Storage of Meclizine:

  • Store Meclizine at room temperature, away from moisture, heat, and direct sunlight.
  • Keep the medication out of the reach of children and pets.
  • Store Meclizine in its original container or packaging, with the lid tightly closed.

Disposal of Meclizine:

  • Do not keep Meclizine that is no longer needed or has expired.
  • Properly dispose of unused or expired medication by following local guidelines or recommendations. Many communities have medication disposal programs or designated drop-off locations to ensure safe disposal.

In case of emergency/overdose

In the event of an emergency or if you suspect an overdose of Meclizine, take the following steps:

  • Contact your local poison control center (1-800-222-1222 in the United States) immediately. They can provide guidance on what to do next.
  • Seek emergency medical attention by calling 911 or going to the nearest emergency room.

What other information should I know

  • Meclizine may cause drowsiness and impair your ability to perform tasks that require alertness, such as driving or operating heavy machinery. Avoid such activities until you know how Meclizine affects you.
  • Avoid alcohol and other substances that can intensify the sedative effects of Meclizine.
  • If you are scheduled for any surgical procedures, inform your surgeon or anesthesiologist that you are taking Meclizine.
  • Meclizine may interact with certain medications, so inform your healthcare provider about all the medications, vitamins, and supplements you are taking.
  • Inform your healthcare provider if you experience any allergic reactions, severe dizziness, or other unusual or severe side effects while taking Meclizine.
  • Follow your healthcare provider’s instructions regarding the dosing and duration of Meclizine treatment. Do not exceed the recommended dosage unless instructed by your healthcare provider.
  • Meclizine’s safety during pregnancy and breastfeeding is not well established, so consult with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.
  • Keep a list of all your medications and share it with your healthcare provider to help prevent potential drug interactions.

Always follow your healthcare provider’s advice and the medication instructions provided with Meclizine to ensure safe and effective use of the medication. If you have any questions or concerns, don’t hesitate to reach out to your healthcare provider or pharmacist for guidance.

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