PrescriptionGiant is a FREE prescription savings program that can save you up to 75% on your prescriptions with or without insurance!

Yondelis (Generic Trabectedin Injection)

Actual product appearance may differ slightly.

Click the CARD below to print or take a screenshot on your mobile phone or tablet. There is no need to download another app!

If you would like to personalize your card enter your full name in the member name field below the card at this link and click the Update button.

Why is this medication prescribed?

Trabectedin is prescribed for the treatment of specific types of cancer, primarily soft tissue sarcoma. Soft tissue sarcoma is a type of cancer that develops in tissues such as muscles, fat, tendons, and joint capsules. Trabectedin is used when other treatments, such as chemotherapy, have not been effective or when the cancer has progressed.

The primary mechanism of trabectedin involves inhibiting the growth and spread of cancer cells. It is classified as an antineoplastic or cytotoxic agent, meaning it works to destroy or inhibit the growth of cancer cells.

How should this medicine be used?

The use of Trabectedin is guided by healthcare professionals, typically oncologists or healthcare providers with expertise in cancer treatment. It is administered intravenously (IV), and the specific details of its use are as follows:

  • Dosage: The dosage of Trabectedin can vary based on factors such as the type and stage of cancer, the patient’s overall health, and any other medications they may be taking. The healthcare provider will determine the appropriate dosage.
  • Administration: Trabectedin is administered as an intravenous infusion, which means it is delivered directly into a vein. This is typically done in a hospital or clinic setting by a healthcare professional.
  • Frequency of Administration: The frequency of Trabectedin administration is determined by the treatment plan designed by the oncologist. Treatment cycles are often repeated every three weeks, but this can vary.
  • Monitoring: Regular monitoring is essential during treatment with Trabectedin. This includes periodic blood tests to assess the patient’s blood cell counts and overall health. It allows healthcare providers to monitor the patient’s response to the treatment and manage any potential side effects.
  • Duration of Treatment: The duration of Trabectedin treatment varies based on the specific cancer being treated and how the patient responds to the medication. Treatment plans are individualized, and the oncologist will assess the effectiveness of the treatment over time.
  • Precautions and Side Effects: Patients receiving Trabectedin should be aware of potential side effects, and they should report any unusual symptoms to their healthcare provider promptly. Common side effects may include nausea, fatigue, and changes in blood cell counts. Serious side effects can also occur, so close monitoring is important.
  • Pregnancy and Breastfeeding: Trabectedin can cause harm to an unborn baby, so it’s crucial for patients to inform their healthcare provider if they are pregnant or planning to become pregnant. Breastfeeding is not recommended during treatment with Trabectedin.

It is important for patients to follow their healthcare provider’s instructions carefully and communicate openly about any concerns or side effects experienced during treatment. The healthcare team will provide guidance on managing side effects and adjusting the treatment plan as needed.

Other uses for this medicine

Trabectedin is primarily used for the treatment of specific types of cancer, particularly soft tissue sarcoma. However, always consult with a healthcare professional for the most current and accurate information.

What special precautions should I follow?

Special Precautions for Trabectedin Injection:

  • Pregnancy and Breastfeeding: Trabectedin can cause harm to an unborn baby, so it is important to inform the healthcare provider if you are pregnant or planning to become pregnant. Similarly, breastfeeding is not recommended during treatment with Trabectedin.
  • Liver Function: Trabectedin is metabolized by the liver, and its use may affect liver function. Therefore, individuals with pre-existing liver conditions or abnormalities may require special monitoring and adjustments to the treatment plan.
  • Blood Cell Counts: Trabectedin can affect blood cell counts, including white blood cells, red blood cells, and platelets. Regular blood tests are typically conducted to monitor these counts during treatment. If levels become too low, it may increase the risk of infection or bleeding.
  • Kidney Function: While kidney function is generally not a primary concern with Trabectedin, individuals with pre-existing kidney conditions may require careful monitoring.
  • Allergies and Hypersensitivity: Inform your healthcare provider about any known allergies or hypersensitivity reactions to medications. Reactions to Trabectedin can include severe infusion reactions, and precautions may be taken to manage this risk.
  • Drug Interactions: Inform your healthcare provider about all medications, including prescription and over-the-counter drugs, as well as dietary supplements and herbal products. Some medications may interact with Trabectedin, potentially affecting its effectiveness or increasing the risk of side effects.
  • Pre-existing Conditions: Individuals with certain pre-existing medical conditions, such as heart conditions, may require special consideration and monitoring during Trabectedin treatment.
  • Infusion Reactions: Trabectedin is administered through an intravenous infusion, and infusion reactions can occur. These reactions may include fever, chills, shortness of breath, and other symptoms. Healthcare providers typically monitor patients closely during and after infusion to manage potential reactions.

Always follow your healthcare provider’s instructions and communicate openly about your medical history, any ongoing health issues, or concerns. The information provided here is general, and specific precautions can vary based on individual circumstances. Your healthcare team will tailor the treatment plan and precautions based on your specific health profile and the nature of the cancer being treated.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Trabectedin. However, it’s important to maintain a balanced and nutritious diet to support overall health and well-being, especially during cancer treatment. Consult with a registered dietitian or healthcare provider for personalized dietary advice based on your individual health needs and any side effects you may be experiencing.

What should I do if I forget a dose?

Trabectedin is typically administered by healthcare professionals in a controlled setting, such as a hospital or clinic. Therefore, patients do not self-administer doses, and the risk of missing a dose is low.

What side effects can this medication cause?

Trabectedin, like many chemotherapy medications, can cause side effects. It’s important to note that not everyone will experience these side effects, and their severity can vary from person to person. Additionally, some side effects may be more common, while others are less likely but potentially more severe. Common side effects of Trabectedin may include:

  • Nausea and Vomiting: Gastrointestinal symptoms such as nausea and vomiting are common side effects. Medications can be prescribed to help manage these symptoms.
  • Fatigue: Feeling tired or fatigued is a common side effect of many cancer treatments, including Trabectedin.
  • Low Blood Cell Counts: Trabectedin can affect the bone marrow, leading to low blood cell counts. This includes low white blood cell counts (neutropenia), low red blood cell counts (anemia), and low platelet counts (thrombocytopenia). This can increase the risk of infections, anemia, and bleeding.
  • Liver Function Abnormalities: Trabectedin is metabolized in the liver, and it can cause abnormalities in liver function tests. Regular monitoring of liver function is typically done during treatment.
  • Infusion Reactions: Infusion reactions may occur during or shortly after the administration of Trabectedin. These reactions can include symptoms such as fever, chills, flushing, shortness of breath, and changes in blood pressure. Healthcare providers monitor patients closely during and after infusion to manage and mitigate these reactions.
  • Muscle Pain and Weakness: Trabectedin can cause muscle pain and weakness. This is a distinctive side effect known as myalgia and is often managed with supportive care measures.
  • Joint Pain: Some individuals may experience joint pain as a side effect of Trabectedin.
  • Headache: Headaches are reported in some patients receiving Trabectedin.
  • Changes in Blood Electrolytes: Trabectedin can cause changes in blood electrolyte levels, including abnormalities in potassium and magnesium. These are typically monitored and managed as needed.

It’s important for patients to communicate with their healthcare team about any side effects or symptoms experienced during treatment. Some side effects may require medical intervention or adjustment of the treatment plan. Additionally, the healthcare team may provide medications or other supportive measures to alleviate symptoms and improve the patient’s overall well-being.

Patients should be aware that while the above list includes common side effects, there may be other, less common side effects. Each individual’s response to treatment is unique, and healthcare providers will tailor their approach based on the patient’s specific situation.

What should I know about storage and disposal of this medication?

Storage and Disposal:

  • Storage:
    • Trabectedin is usually administered by healthcare professionals in a clinical setting. If you are given the medication to take at home, follow your healthcare provider’s instructions on storage.
    • Generally, it should be stored at room temperature, away from light and moisture.
  • Disposal:
    • Dispose of Trabectedin according to your local regulations for hazardous waste disposal.
    • Do not flush it down the toilet or pour it into a drain unless specifically instructed to do so.
    • Check with your healthcare provider or pharmacist about the proper disposal method in your area.

In case of emergency/overdose

In the case of an emergency or suspected overdose, seek immediate medical attention. Emergency symptoms or signs of overdose may include severe infusion reactions, severe myelosuppression (low blood cell counts), or other serious adverse effects.

What other information should I know?

  • Medical History: Inform your healthcare provider about your complete medical history, including any pre-existing conditions, allergies, or medications you are taking.
  • Follow-up Appointments: Attend all scheduled follow-up appointments with your healthcare provider. These appointments are important for monitoring your response to treatment, managing side effects, and making any necessary adjustments to your treatment plan.
  • Communication: Keep open communication with your healthcare team. Report any new or worsening symptoms, side effects, or concerns promptly.
  • Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss this with your healthcare provider. Trabectedin may cause harm to a developing fetus, and precautions are necessary.

Always follow the specific instructions provided by your healthcare provider and the medication’s packaging. If you have questions or concerns about Trabectedin or its administration, consult with your healthcare team for personalized guidance.

Copyright © 2023