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Triotann (Generic Chlorpheniramine)

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Why is this medication prescribed?

Chlorpheniramine is an antihistamine medication that is commonly prescribed to relieve symptoms associated with allergic conditions, such as hay fever (allergic rhinitis), allergic conjunctivitis, and other respiratory allergies. It can also be used to manage symptoms like itching, sneezing, runny nose, and watery eyes caused by allergies.

The primary mode of action of chlorpheniramine is to block the effects of histamine, a substance released by the body during an allergic reaction. By blocking histamine, chlorpheniramine helps alleviate allergy symptoms.

How should this medicine be used?

Here are some general guidelines for using chlorpheniramine:

  • Dosage: Follow your healthcare provider’s instructions or the recommended dosage on the product label. Do not exceed the prescribed or recommended dose.
  • Administration: Chlorpheniramine is usually taken orally with or without food. It is available in various forms, including tablets, capsules, and liquid. Make sure to use the appropriate dosage form as prescribed.
  • Avoid alcohol: Consumption of alcohol may enhance the sedative effects of chlorpheniramine. It’s advisable to avoid alcohol while taking this medication.
  • Caution with other medications: Inform your healthcare provider about all the medications you are taking, including prescription, over-the-counter, herbal supplements, and vitamins. Some medications may interact with chlorpheniramine.
  • Drowsiness: Be cautious when performing activities that require alertness, such as driving or operating machinery, as chlorpheniramine may cause drowsiness.
  • Pregnancy and breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the use of chlorpheniramine with your healthcare provider to assess the potential risks and benefits.

As with any medication, it’s crucial to consult with your healthcare provider before starting or discontinuing the use of chlorpheniramine, especially if you have any pre-existing medical conditions or are taking other medications.

Other uses for this medicine

In addition to its primary use for relieving allergic symptoms, chlorpheniramine may be used in the treatment of other conditions. Some of these include:

  • Common Cold: Chlorpheniramine may be included in over-the-counter cold and cough preparations to help alleviate symptoms such as sneezing, runny nose, and congestion.
  • Motion Sickness: Due to its ability to reduce symptoms like nausea and vomiting, chlorpheniramine may be used in the management of motion sickness.
  • Itching and Hives: Chlorpheniramine can be used to relieve itching associated with various skin conditions, including hives (urticaria).

What special precautions should I follow?

Special precautions should be taken when using chlorpheniramine, and it’s important to discuss your medical history and any other medications you may be taking with your healthcare provider. Here are some general precautions:

  • Allergies: Inform your healthcare provider if you are allergic to chlorpheniramine or any other antihistamines.
  • Medical Conditions: Let your healthcare provider know about any existing medical conditions, especially those related to the respiratory system, heart, liver, kidney, high blood pressure, glaucoma, or an enlarged prostate.
  • Pregnancy and Breastfeeding: If you are pregnant or breastfeeding, discuss the use of chlorpheniramine with your healthcare provider to determine its safety for you and your baby.
  • Central Nervous System Depression: Chlorpheniramine may cause drowsiness and impair your ability to perform tasks that require alertness. Avoid activities such as driving or operating heavy machinery until you know how the medication affects you.
  • Alcohol and Sedatives: Avoid or limit the consumption of alcohol and other sedatives while taking chlorpheniramine, as they can enhance the sedative effects of the medication.
  • Drug Interactions: Inform your healthcare provider about all the medications you are taking, as chlorpheniramine may interact with certain drugs, including other antihistamines, tranquilizers, and monoamine oxidase inhibitors (MAOIs).

Always follow your healthcare provider’s recommendations and the instructions on the medication label. If you experience any concerning side effects or have questions about the use of chlorpheniramine, consult with your healthcare provider.

What special dietary instructions should I follow?

Regarding dietary instructions, there are no specific dietary restrictions associated with chlorpheniramine. However, it’s always a good idea to maintain a healthy and balanced diet, especially if you have underlying health conditions. If you have concerns about potential interactions between chlorpheniramine and specific foods or nutrients, it’s advisable to discuss them with your healthcare provider.

What should I do if I forget a dose?

If you forget a dose of chlorpheniramine, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one. If you have any concerns or questions about missed doses, consult with your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Chlorpheniramine, like any medication, can cause side effects. It’s important to note that not everyone will experience these side effects, and the severity can vary from person to person. Common side effects of chlorpheniramine include:

  • Drowsiness: Chlorpheniramine can cause drowsiness or sedation, which may impair your ability to concentrate or perform tasks requiring alertness. It’s advisable to avoid activities such as driving or operating heavy machinery until you know how the medication affects you.
  • Dry Mouth: This medication may lead to a dry mouth, which can be alleviated by staying hydrated with water or sugar-free beverages.
  • Blurred Vision: Chlorpheniramine may cause temporary blurred vision. Avoid activities that require clear vision until your vision returns to normal.
  • Constipation: Some individuals may experience constipation while taking chlorpheniramine. Maintaining a well-balanced diet with fiber-rich foods and staying hydrated can help prevent or relieve constipation.
  • Urinary Retention: Chlorpheniramine can cause difficulty in urination in some individuals, especially in those with an enlarged prostate. If you experience any problems with urination, inform your healthcare provider.
  • Dizziness: Chlorpheniramine may cause dizziness or lightheadedness. Avoid sudden changes in position, such as standing up quickly, to minimize the risk of dizziness.
  • Nausea: Some people may experience nausea while taking chlorpheniramine. Taking the medication with food may help alleviate this side effect.

It’s important to seek medical attention if you experience severe or persistent side effects. Additionally, allergic reactions to chlorpheniramine are possible but rare. Seek immediate medical attention if you develop symptoms such as rash, itching, swelling, severe dizziness, or difficulty breathing.

Inform your healthcare provider about any side effects you may be experiencing. They can provide guidance on managing side effects or adjust your treatment plan if necessary. Remember to follow your healthcare provider’s instructions and not to exceed the recommended dosage to minimize the risk of side effects.

What should I know about storage and disposal of this medication?

Storage and disposal guidelines for chlorpheniramine:


  • Keep chlorpheniramine in its original packaging or container to protect it from light and moisture.
  • Store the medication at room temperature, away from heat and direct sunlight.
  • Keep chlorpheniramine out of reach of children and pets.
  • Do not store it in the bathroom, as moisture and heat can affect the stability of the medication.


  • Dispose of expired or unused chlorpheniramine properly. Follow any specific disposal instructions provided by your healthcare provider or pharmacist.
  • Do not flush medications down the toilet unless instructed to do so. Check with your local pharmacy or waste disposal facility for proper disposal methods in your area.
  • Consider using drug take-back programs if available in your community.

In case of emergency/overdose

If you suspect an overdose or experience severe symptoms, seek emergency medical attention immediately. Symptoms of chlorpheniramine overdose may include extreme drowsiness, confusion, hallucinations, seizures, or difficulty breathing.

What other information should I know?

  • Avoid Alcohol: Limit or avoid alcohol while taking chlorpheniramine, as it may enhance the sedative effects of the medication.
  • Medical Appointments: Keep scheduled follow-up appointments with your healthcare provider to monitor your response to chlorpheniramine and address any concerns or adjustments needed.
  • Inform Healthcare Providers: Inform all healthcare providers involved in your care about your use of chlorpheniramine, including dentists and specialists. This information is important for avoiding potential drug interactions.
  • Allergies: If you develop signs of an allergic reaction (e.g., rash, itching, swelling, severe dizziness, difficulty breathing), seek immediate medical attention.
  • Driving and Operating Machinery: Be cautious when engaging in activities that require alertness, as chlorpheniramine can cause drowsiness.

Always follow your healthcare provider’s instructions and read the medication guide or patient information leaflet provided with the medication. If you have any questions or concerns, consult your healthcare provider or pharmacist for clarification.

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