PrescriptionGiant is a FREE prescription savings program that can save you up to 75% on your prescriptions with or without insurance!

Tri-Luma (Generic Fluocinolone Topical)

Actual product appearance may differ slightly.

Click the CARD below to print or take a screenshot on your mobile phone or tablet. There is no need to download another app!

If you would like to personalize your card enter your full name in the member name field below the card at this link and click the Update button.

Why is this medication prescribed?

Fluocinolone topical is prescribed for the treatment of various skin conditions such as eczema, dermatitis, psoriasis, and certain types of itching. It belongs to a class of medications known as corticosteroids, which work by reducing inflammation, itching, and redness.

How should this medicine be used?

The topical form of fluocinolone comes in different formulations such as creams, ointments, and solutions. The exact instructions for use may vary depending on the specific formulation prescribed by the healthcare provider. However, here are some general guidelines:

  • Clean affected area: Before applying fluocinolone topical, make sure the affected area of the skin is clean and dry.
  • Apply a thin layer: Apply a thin layer of the medication to the affected area(s) of the skin. Gently rub it in until it is absorbed.
  • Frequency of application: Follow the directions provided by your healthcare provider. Typically, fluocinolone topical is applied 2 to 4 times daily, or as directed by your doctor.
  • Do not cover unless directed: Unless directed otherwise by your healthcare provider, it’s generally not recommended to cover the treated area with bandages or dressings after applying fluocinolone topical.
  • Wash hands after use: After applying the medication, wash your hands thoroughly unless you are treating your hands.
  • Avoid contact with eyes and mucous membranes: Be careful to avoid getting the medication in your eyes or on mucous membranes. If accidental contact occurs, rinse thoroughly with water.
  • Do not use on broken or infected skin: Do not apply fluocinolone topical to areas of the skin that are broken, infected, or have open wounds unless directed by your doctor.
  • Do not use for extended periods without doctor’s supervision: Prolonged use of topical corticosteroids may lead to skin thinning, so it’s essential to follow your doctor’s recommendations regarding the duration of treatment.

Always follow the specific instructions provided by your healthcare provider or pharmacist regarding the use of fluocinolone topical. If you have any questions or concerns about how to use this medication, don’t hesitate to consult your healthcare provider for clarification.

Other uses for this medicine

Fluocinolone topical may also be used for other purposes not listed in this medication guide. It is essential to use this medication only for the condition for which it was prescribed and under the guidance of a healthcare professional.

What special precautions should I follow?

Special precautions should be taken when using fluocinolone topical:

  • Avoid prolonged use: Prolonged or excessive use of fluocinolone topical can lead to skin thinning, stretch marks, and other adverse effects. Follow your healthcare provider’s instructions carefully and do not exceed the recommended duration or frequency of use.
  • Avoid contact with eyes and mucous membranes: Take care to avoid getting fluocinolone topical in your eyes, mouth, or other mucous membranes. If accidental contact occurs, rinse thoroughly with water.
  • Use on intact skin only: Fluocinolone topical should only be applied to intact skin and should not be used on broken, infected, or ulcerated skin unless directed by your doctor.
  • Monitor for adverse effects: Watch for signs of skin thinning, such as easy bruising, stretch marks, or changes in skin pigmentation. If you experience any concerning symptoms, contact your healthcare provider promptly.
  • Inform your healthcare provider: Make sure to inform your healthcare provider about any other medications you are taking, as well as any medical conditions you have, to avoid potential drug interactions or complications.

Always follow your healthcare provider’s instructions and advice when using fluocinolone topical or any other medication. If you have any questions or concerns, don’t hesitate to discuss them with your doctor or pharmacist.

What special dietary instructions should I follow?

Regarding special dietary instructions, there are typically no specific dietary restrictions associated with the use of fluocinolone topical. However, it’s always a good idea to maintain a balanced diet and stay hydrated to support overall skin health.

What should I do if I forget a dose?

If you forget to apply a dose of fluocinolone topical, apply it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not apply extra medication to make up for a missed dose. Applying too much can increase the risk of side effects. If you have any concerns or questions about missed doses, consult your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Fluocinolone topical, like any medication, can cause side effects, although not everyone may experience them. Some common side effects of fluocinolone topical include:

  • Skin irritation: This may include burning, stinging, itching, or redness at the application site.
  • Skin thinning: Prolonged use of fluocinolone topical can lead to thinning of the skin, making it more fragile and prone to tearing or bruising.
  • Stretch marks: Long-term use of corticosteroids like fluocinolone can contribute to the development of stretch marks, especially in areas where the skin is frequently stretched, such as the abdomen or thighs.
  • Acne or folliculitis: Some individuals may experience acne or folliculitis (inflammation of hair follicles) as a side effect of fluocinolone topical.
  • Hyperpigmentation: Fluocinolone may cause changes in skin pigmentation, leading to darkening or lightening of the skin at the application site.
  • Allergic reactions: In rare cases, fluocinolone topical can cause allergic reactions such as rash, itching, swelling, dizziness, or trouble breathing. If you experience any signs of an allergic reaction, seek medical attention immediately.
  • Increased hair growth: Prolonged use of fluocinolone topical may cause excessive hair growth (hypertrichosis) at the application site.
  • Infections: In some cases, prolonged use of corticosteroids can increase the risk of skin infections.

It’s essential to discuss any concerns about potential side effects with your healthcare provider before starting fluocinolone topical or any other medication. Additionally, if you experience severe or persistent side effects while using fluocinolone topical, contact your doctor for further evaluation and guidance.

What should I know about storage and disposal of this medication?

Storage and disposal of fluocinolone topical:


  • Store fluocinolone topical at room temperature, away from moisture and heat.
  • Keep the medication out of reach of children and pets.
  • Do not freeze fluocinolone topical unless specifically instructed by the manufacturer.
  • Store the medication in its original container to protect it from light.


  • Dispose of fluocinolone topical according to local regulations or as instructed by your healthcare provider or pharmacist.
  • Do not flush fluocinolone topical down the toilet unless instructed to do so.
  • If you have unused or expired fluocinolone topical, take it to a medication take-back program or dispose of it properly to prevent accidental ingestion by others.

In case of emergency/overdose

In case of emergency or overdose of fluocinolone topical:

  • If someone has swallowed fluocinolone topical or if you suspect an overdose, contact your local poison control center (in the United States, you can call 1-800-222-1222) or seek emergency medical attention immediately.
  • If the medication has been applied excessively to the skin or ingested accidentally, symptoms of overdose may include excessive skin thinning, stretch marks, or other adverse effects.
  • Be prepared to provide information about the amount of fluocinolone topical ingested or applied, as well as the person’s age, weight, and any symptoms they may be experiencing.

What other information should I know?

  • Keep all appointments with your healthcare provider for monitoring and follow-up while using fluocinolone topical.
  • Inform your healthcare provider if your condition worsens or does not improve after using fluocinolone topical as directed.
  • Avoid prolonged sun exposure and tanning beds while using fluocinolone topical, as it may increase the risk of sunburn.
  • Do not use fluocinolone topical on the face, underarms, or groin area unless directed by your doctor, as these areas are more prone to skin thinning and other adverse effects.
  • If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using fluocinolone topical with your healthcare provider before starting treatment.

Always follow your healthcare provider’s instructions and advice when using fluocinolone topical or any other medication, and don’t hesitate to ask questions if you need clarification or additional information.

Copyright © 2023