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Trelegy Ellipta (Generic Fluticasone, Umeclidinium, and Vilanterol Oral Inhalation)

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Why is this medication prescribed?

Trelegy Ellipta is a prescription medication primarily used for the treatment of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema, in adults. It is a combination inhaler containing three active ingredients: fluticasone furoate (an inhaled corticosteroid), umeclidinium (an anticholinergic), and vilanterol (a long-acting beta agonist).

How should this medicine be used?

Here’s how Trelegy Ellipta is typically used:

  • Dosage: The usual dose is one inhalation once daily. The strength of each ingredient is fixed in the inhaler device, so the dosage is standardized.
  • Administration: Trelegy Ellipta is an inhalation powder and is administered orally via inhalation through the mouth using the Ellipta inhaler device provided. It’s important to inhale the medication exactly as prescribed by your healthcare provider.
  • Preparation: Before using the inhaler for the first time, you need to prepare it. This usually involves opening the cover, loading a dose, and priming the inhaler.
  • Inhalation Technique: Hold the inhaler in the upright position, put your thumb on the thumb grip and slide it back until the mouthpiece fully appears. Breathe out gently away from the inhaler. Place the mouthpiece between your lips and close your lips firmly around it. Inhale steadily and deeply through your mouth. Do not breathe in through your nose. Remove the inhaler from your mouth and hold your breath for about 3-4 seconds or as long as comfortable. Breathe out slowly and gently away from the inhaler. Close the inhaler cover.
  • Cleaning: It’s essential to keep the inhaler clean and dry. You can wipe the mouthpiece with a dry tissue or clean cloth, but do not wash or put it in water.
  • Frequency: Trelegy Ellipta is typically used once daily, at the same time each day, unless otherwise directed by your doctor.
  • Storage: Store the inhaler at room temperature away from moisture and heat.

It’s crucial to follow the specific instructions provided by your healthcare provider or pharmacist regarding the correct usage of Trelegy Ellipta. If you have any questions or concerns about how to use this medication, don’t hesitate to consult your healthcare provider for guidance.

Other uses for this medicine

Trelegy Ellipta is primarily indicated for the treatment of COPD, including chronic bronchitis and emphysema, in adults. It is not typically prescribed for other conditions. However, as with many medications, there may be off-label uses or experimental uses being explored, but these would need to be discussed with a healthcare professional.

What special precautions should I follow?

Regarding special precautions for using Trelegy Ellipta, here are some important points to keep in mind:

  • Allergies: Inform your healthcare provider if you are allergic to any of the active or inactive ingredients in Trelegy Ellipta. This medication contains fluticasone, so individuals with a known allergy to corticosteroids should use Trelegy Ellipta with caution.
  • Medical Conditions: Before using Trelegy Ellipta, discuss your medical history with your healthcare provider, especially if you have a history of certain medical conditions such as tuberculosis, glaucoma, diabetes, heart disease, high blood pressure, osteoporosis, or any other respiratory conditions.
  • Pregnancy and Breastfeeding: Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. The safety of Trelegy Ellipta during pregnancy and breastfeeding has not been established, and your doctor will weigh the potential benefits and risks before prescribing it.
  • Interactions: Inform your healthcare provider about all the medications you are currently taking, including prescription, over-the-counter, herbal supplements, and vitamins. Certain medications may interact with Trelegy Ellipta, potentially increasing the risk of side effects or reducing its effectiveness.
  • Worsening Symptoms: Trelegy Ellipta is not a rescue medication for sudden breathing problems. If your breathing symptoms worsen suddenly, use a rescue inhaler as prescribed by your doctor. Contact your healthcare provider immediately if you experience worsening symptoms or if you require more medication than usual to control your symptoms.
  • Routine Monitoring: Regular monitoring by your healthcare provider is important while using Trelegy Ellipta to ensure it is effectively managing your COPD symptoms and to monitor for any potential side effects or complications.
  • Adherence to Instructions: Follow the prescribed dosage and administration instructions carefully. Do not exceed the recommended dose or frequency of use without consulting your healthcare provider.

Always consult with your healthcare provider or pharmacist for personalized advice and guidance regarding the use of Trelegy Ellipta, especially if you have specific health concerns or questions.

What special dietary instructions should I follow?

Regarding special dietary instructions, there are no specific dietary restrictions associated with Trelegy Ellipta. However, maintaining a healthy diet as advised by your healthcare provider is generally recommended for overall health and well-being.

What should I do if I forget a dose?

If you forget a dose of Trelegy Ellipta, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. If you are unsure about what to do, consult your healthcare provider or pharmacist for advice. It’s important to maintain a consistent dosing schedule for optimal management of your condition.

What side effects can this medication cause?

Trelegy Ellipta, like any medication, can cause side effects in some people. Common side effects of Trelegy Ellipta may include:

  • Upper respiratory tract infections: Such as colds or flu-like symptoms.
  • Headache: Mild to moderate headaches may occur.
  • Pharyngitis: Inflammation of the throat may occur, leading to soreness or discomfort.
  • Sinusitis: Inflammation of the sinuses may occur, leading to symptoms such as congestion or facial pain.
  • Cough: Some individuals may experience coughing as a side effect.
  • Pneumonia: Although uncommon, pneumonia can occur as a side effect of Trelegy Ellipta.
  • Bone fractures: Long-term use of corticosteroids, such as fluticasone furoate in Trelegy Ellipta, may increase the risk of bone fractures, especially in older adults.
  • Oropharyngeal candidiasis (thrush): Fungal infections in the mouth and throat may occur, leading to symptoms such as white patches, soreness, or difficulty swallowing.
  • Increased blood pressure: In some cases, Trelegy Ellipta may lead to elevated blood pressure.
  • Glaucoma or cataracts: Long-term use of corticosteroids may increase the risk of developing eye conditions such as glaucoma or cataracts.
  • Adrenal insufficiency: Rarely, corticosteroids can suppress adrenal gland function, leading to adrenal insufficiency.

It’s important to note that not everyone will experience these side effects, and some individuals may experience side effects not listed here. Additionally, some side effects may be more severe or require medical attention. If you experience any unusual or bothersome symptoms while taking Trelegy Ellipta, it’s essential to contact your healthcare provider for further evaluation and guidance.

What should I know about storage and disposal of this medication?

Here’s what you should know about storage and disposal of Trelegy Ellipta:

  • Storage: Store Trelegy Ellipta at room temperature away from moisture, heat, and direct sunlight. The inhaler should be kept in its protective foil tray until ready to use. Keep it out of reach of children and pets.
  • Disposal: After all doses have been used, the inhaler should be discarded. Do not try to refill or reuse the inhaler device. Dispose of the used inhaler in a safe manner according to local regulations. It’s recommended to check with your pharmacist or healthcare provider for guidance on proper disposal methods specific to your area.

In case of emergency/overdose

In case of emergency or overdose of Trelegy Ellipta, seek immediate medical attention or contact a poison control center. Overdose symptoms may include severe headache, pounding in your neck or ears, chest pain, fast or pounding heartbeats, tremors, or nervousness.

What other information should I know?

  • Regular Monitoring: Your healthcare provider may periodically monitor your lung function and overall health while you are using Trelegy Ellipta to ensure it is effectively managing your COPD symptoms and to monitor for any potential side effects or complications.
  • Do Not Exceed Recommended Dose: Take Trelegy Ellipta exactly as prescribed by your healthcare provider. Do not exceed the recommended dose or frequency of use unless instructed to do so by your doctor.
  • Inform Healthcare Providers: Make sure to inform all healthcare providers involved in your care that you are using Trelegy Ellipta, including your primary care physician, specialists, and dentists. This is important for coordinating your overall healthcare and avoiding potential drug interactions.
  • Regular Follow-up: Attend scheduled follow-up appointments with your healthcare provider to assess your response to treatment and make any necessary adjustments to your medication regimen.
  • Educate Yourself: Familiarize yourself with the proper technique for using the Trelegy Ellipta inhaler, as proper inhaler technique is crucial for effective medication delivery to the lungs. If you have any questions or concerns about how to use the inhaler, don’t hesitate to ask your healthcare provider or pharmacist for guidance.
  • Keep a Record: Consider keeping a record of your symptoms, medication use, and any changes in your condition to share with your healthcare provider during appointments. This information can help your provider assess your response to treatment and make any necessary adjustments to your care plan.
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