PrescriptionGiant is a FREE prescription savings program that can save you up to 75% on your prescriptions with or without insurance!

Tranxene (Generic Clorazepate)

Actual product appearance may differ slightly.

Click the CARD below to print or take a screenshot on your mobile phone or tablet. There is no need to download another app!

If you would like to personalize your card enter your full name in the member name field below the card at this link and click the Update button.


Taking Tranxene (clorazepate) carries certain risks, particularly when used for an extended period or in higher doses. Some of the risks associated with Tranxene include:

  • Dependence and Withdrawal: Tranxene belongs to the benzodiazepine class of drugs, which have the potential for physical and psychological dependence with prolonged use. Abrupt discontinuation or rapid dosage reduction can lead to withdrawal symptoms, including anxiety, agitation, insomnia, tremors, and seizures.
  • Tolerance: With continued use, the body may develop tolerance to Tranxene, requiring higher doses to achieve the same therapeutic effect. This can increase the risk of dependence and other adverse effects.
  • Sedation and Impairment: Tranxene can cause drowsiness, dizziness, and impair cognitive and motor functions. This can affect your ability to perform tasks that require mental alertness, such as driving or operating machinery, potentially leading to accidents or injuries.
  • Respiratory Depression: In high doses or when combined with other central nervous system depressants such as alcohol or opioids, Tranxene can suppress respiratory function, leading to difficulty breathing or even respiratory failure, especially in vulnerable individuals.
  • Memory and Cognitive Impairment: Long-term use of Tranxene may impair memory, concentration, and cognitive function, particularly in older adults. This can impact daily functioning and quality of life.
  • Risk of Abuse: Tranxene has the potential for misuse and abuse, particularly among individuals with a history of substance abuse or addiction. Misuse of Tranxene can lead to serious health consequences, including overdose and death.
  • Interactions with Other Medications: Tranxene can interact with other medications, including alcohol, opioids, and certain antidepressants, increasing the risk of side effects or overdose. It’s essential to inform your healthcare provider about all medications you are taking to avoid potentially harmful interactions.
  • Increased Fall Risk: Due to its sedative effects, Tranxene can increase the risk of falls, particularly in older adults. Falls can result in fractures, head injuries, and other serious complications.

It’s important to use Tranxene cautiously and under the guidance of a healthcare professional. Always follow your doctor’s instructions regarding dosage, duration of treatment, and precautions to minimize the risks associated with Tranxene use. If you have any concerns about taking Tranxene, discuss them with your doctor.

Why is this medication prescribed?

Tranxene, also known as clorazepate, is a medication primarily prescribed for the management of anxiety disorders, such as generalized anxiety disorder (GAD) and panic disorder. It belongs to a class of drugs called benzodiazepines, which act on the central nervous system to produce a calming effect.

Tranxene is typically used for short-term relief of anxiety symptoms due to its potential for tolerance and dependence with long-term use. It may also be prescribed to alleviate symptoms of alcohol withdrawal and muscle spasms.

How should this medicine be used?

Here are some general guidelines for the use of Tranxene:

  • Dosage: The dosage will vary based on your condition and response to treatment. Your doctor will start you on the lowest effective dose and adjust it gradually if needed.
  • Administration: Tranxene is usually taken orally in the form of tablets or capsules. It’s important to take it exactly as prescribed by your doctor. Do not increase or decrease the dosage without consulting your doctor first.
  • Timing: Tranxene may be taken with or without food. Follow your doctor’s instructions regarding the timing of doses.
  • Avoid alcohol: Avoid consuming alcohol while taking Tranxene, as it can increase the sedative effects of the medication and potentially lead to dangerous side effects.
  • Duration: Tranxene is typically prescribed for short-term use due to the risk of tolerance, dependence, and withdrawal symptoms with prolonged use. Do not use Tranxene for longer than prescribed without consulting your doctor.
  • Withdrawal: If you have been using Tranxene for an extended period and need to stop, it’s essential to do so under the guidance of your doctor to avoid withdrawal symptoms. Your doctor may gradually taper the dosage to minimize withdrawal effects.
  • Side effects: Be aware of potential side effects of Tranxene, including drowsiness, dizziness, blurred vision, headache, nausea, and confusion. If you experience severe or persistent side effects, contact your doctor.

Always keep your doctor informed about any other medications, supplements, or health conditions you have, as they can interact with Tranxene. Additionally, never share Tranxene with others, especially those with a history of substance abuse, as it can be habit-forming.

Other uses for this medicine

In addition to its primary use in managing anxiety disorders, Tranxene (clorazepate) may also be prescribed for other conditions or purposes, as determined by your healthcare provider. These may include:

  • Alcohol Withdrawal: Tranxene can be used to alleviate symptoms of alcohol withdrawal, such as tremors, agitation, and anxiety.
  • Muscle Spasms: Tranxene may be prescribed to relieve muscle spasms or muscle tightness associated with certain conditions.
  • Seizure Disorders: In some cases, Tranxene may be used as an adjunctive treatment for certain types of seizure disorders, particularly when other medications have not been effective.
  • Insomnia: Tranxene might be prescribed for short-term management of insomnia, although this is less common due to its potential for dependence and tolerance.

What special precautions should I follow?

Special precautions to consider when taking Tranxene include:

  • Risk of Dependence: Tranxene belongs to the benzodiazepine class of drugs, which have a potential for tolerance, dependence, and withdrawal symptoms, particularly with long-term use or high doses. Follow your doctor’s instructions carefully and avoid using Tranxene for longer than prescribed.
  • Avoid Alcohol: Consumption of alcohol should be avoided while taking Tranxene, as it can increase the sedative effects of the medication and potentially lead to dangerous side effects or overdose.
  • Central Nervous System Depression: Tranxene can cause drowsiness, dizziness, and impair cognitive and motor skills. Use caution when driving, operating machinery, or engaging in activities that require alertness until you know how Tranxene affects you.
  • Medical Conditions: Inform your doctor about any medical conditions you have, especially respiratory conditions, liver disease, kidney disease, glaucoma, or a history of substance abuse, as they may affect the dosage or safety of Tranxene.
  • Pregnancy and Breastfeeding: Tranxene should be used with caution during pregnancy, especially during the first trimester, as it may increase the risk of congenital malformations. It can also pass into breast milk, so consult your doctor before breastfeeding while taking Tranxene.
  • Interactions: Inform your doctor about all medications, supplements, and herbal products you are taking, as they can interact with Tranxene, potentially increasing the risk of side effects or reducing its effectiveness.

Always follow your doctor’s instructions and guidance when taking Tranxene, and promptly report any concerning side effects or changes in your condition.

What special dietary instructions should I follow?

Regarding special dietary instructions, there are no specific dietary restrictions associated with taking Tranxene. However, maintaining a balanced and healthy diet is generally recommended for overall well-being.

What should I do if I forget a dose?

If you forget to take a dose of Tranxene, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. If you have any concerns or questions about missed doses, consult your doctor or pharmacist for guidance.

What side effects can this medication cause?

Tranxene (clorazepate) can cause various side effects, although not everyone will experience them. Common side effects may include:

  • Drowsiness
  • Dizziness
  • Fatigue
  • Blurred vision
  • Headache
  • Nausea or vomiting
  • Dry mouth
  • Constipation
  • Changes in appetite
  • Difficulty concentrating
  • Memory impairment
  • Muscle weakness
  • Slurred speech
  • Increased saliva production
  • Changes in libido

These side effects are typically mild and transient, resolving as your body adjusts to the medication. However, if any of these side effects persist or worsen, inform your doctor promptly.

In some cases, Tranxene may cause more serious side effects that require medical attention. These can include:

  • Allergic reactions, such as rash, itching, swelling of the face, lips, or tongue, or difficulty breathing
  • Mood changes, such as agitation, aggression, or hallucinations
  • Depression or suicidal thoughts
  • Confusion or disorientation
  • Unusual changes in behavior
  • Difficulty breathing or swallowing
  • Irregular heartbeat
  • Severe dizziness or fainting
  • Uncontrolled muscle movements
  • Jaundice (yellowing of the skin or eyes)
  • Signs of infection, such as fever or chills

If you experience any severe or concerning side effects while taking Tranxene, seek medical attention immediately. Additionally, inform your healthcare provider about all side effects you experience, even if they are not listed here.

What should I know about storage and disposal of this medication?

Storage and Disposal:

  • Storage: Store Tranxene at room temperature away from light and moisture. Avoid storing it in the bathroom or kitchen, where humidity can affect its stability. Keep the medication out of reach of children and pets.
  • Disposal: Dispose of any unused or expired Tranxene properly. Do not flush it down the toilet or pour it down the drain unless instructed to do so by your pharmacist or local waste disposal company. Instead, consult your pharmacist or local waste management authority on how to safely dispose of medications.

In case of emergency/overdose

In case of emergency or overdose of Tranxene, take the following steps:

  • Seek Immediate Medical Attention: If you suspect an overdose or experience severe symptoms such as difficulty breathing, loss of consciousness, severe drowsiness, or confusion, call emergency services (such as 911 in the United States) or go to the nearest emergency room.
  • Provide Information: If possible, provide medical personnel with information about the medication, including the name (Tranxene), dosage strength, and the amount ingested. This will help them assess the situation and provide appropriate treatment.
  • Do Not Attempt Self-Help Measures: Avoid attempting to treat an overdose at home without medical guidance. Certain measures, such as inducing vomiting, may not be appropriate and could exacerbate the situation.

What other information should I know?

  • Regular Monitoring: Your doctor may need to monitor your progress regularly while taking Tranxene to assess its effectiveness and monitor for side effects.
  • Avoid Abrupt Discontinuation: Do not stop taking Tranxene suddenly without consulting your doctor, as this can lead to withdrawal symptoms. Your doctor may need to taper the dosage gradually to safely discontinue the medication.
  • Avoid Driving or Operating Machinery: Tranxene may cause drowsiness, dizziness, or impair cognitive and motor functions, which can affect your ability to drive or operate machinery. Use caution until you know how Tranxene affects you.
  • Medical Alert: Inform healthcare providers, including dentists and emergency personnel, that you are taking Tranxene, as it may interact with other medications or affect treatment decisions.
  • Keep Appointments: Attend all scheduled appointments with your doctor to monitor your progress and discuss any concerns or changes in your condition.

Always follow your doctor’s instructions and guidance when taking Tranxene, and do not hesitate to seek medical attention if you have any questions, concerns, or experience adverse effects.

Copyright © 2023