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Topicort LP (Generic Desoximetasone Topical)

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Why is this medication prescribed?

Topicort LP (desoximetasone) is prescribed to treat various inflammatory skin conditions, including:

  • Eczema: It can help alleviate symptoms such as itching, redness, and inflammation associated with eczema, also known as atopic dermatitis.
  • Psoriasis: Topicort LP can be used to manage the symptoms of psoriasis, including red, scaly patches of skin.
  • Dermatitis: It is effective in treating different types of dermatitis, such as allergic contact dermatitis, irritant contact dermatitis, and seborrheic dermatitis.
  • Rash: Topicort LP may also be prescribed to treat certain types of rash, particularly those caused by allergic reactions or inflammation.

Overall, Topicort LP works by reducing inflammation, itching, and redness associated with these skin conditions, providing relief to individuals suffering from these symptoms.

How should this medicine be used?

Here’s how Topicort LP should be used:

  • Clean the affected area: Wash your hands and the affected area with mild soap and water and pat dry with a clean towel.
  • Apply a thin layer: Squeeze a small amount of Topicort LP onto your fingertip and gently rub it into the affected area until it is evenly distributed. It’s important not to use more medication than prescribed as excessive use can lead to unwanted side effects.
  • Avoid sensitive areas: Take care to avoid getting the medication in your eyes, mouth, or nose, and do not apply it to broken or infected skin unless directed by your doctor.
  • Wash hands after application: After applying Topicort LP, wash your hands thoroughly to remove any medication residue and prevent unintentional transfer to other parts of the body or contact with mucous membranes.
  • Use as directed: Follow your doctor’s instructions carefully regarding the frequency and duration of application. Do not use Topicort LP for longer than prescribed or apply it to larger areas of skin than recommended, as this can increase the risk of side effects.
  • Monitor for improvement: Pay attention to how your skin responds to the medication. If there is no improvement or if your condition worsens, contact your doctor.
  • Do not stop abruptly: If you need to stop using Topicort LP, do not discontinue it abruptly. Gradually taper off its use as directed by your doctor to prevent potential rebound effects.

It’s essential to use Topicort LP exactly as prescribed by your doctor and to consult with them if you have any questions or concerns about its use or if you experience any side effects.

Other uses for this medicine

While Topicort LP (desoximetasone) is primarily prescribed for inflammatory skin conditions such as eczema, dermatitis, and psoriasis, it may also be used for other purposes as determined by your healthcare provider. However, any alternative uses should be under the supervision and guidance of a qualified medical professional.

What special precautions should I follow?

Special precautions to consider when using Topicort LP include:

  • Avoiding sensitive areas: Take care to avoid applying Topicort LP to sensitive areas such as the face, groin, or armpits unless specifically instructed by your doctor.
  • Limiting use on large areas: Prolonged or excessive use of Topicort LP over large areas of the body may increase the risk of systemic absorption and side effects. Follow your doctor’s instructions regarding the quantity and frequency of application.
  • Avoiding occlusive dressings: Unless directed by your doctor, do not cover the treated area with occlusive dressings (bandages or wraps) as this may increase the absorption of the medication and the risk of side effects.
  • Monitoring for side effects: Be vigilant for any signs of skin thinning, discoloration, stretch marks, or other adverse effects at the site of application. Report any concerning symptoms to your healthcare provider promptly.
  • Interactions with other medications: Inform your doctor about any other medications, including over-the-counter products and supplements, that you are currently taking, as they may interact with Topicort LP.
  • Pregnancy and breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of using Topicort LP with your doctor. While topical corticosteroids are generally considered safe during pregnancy and breastfeeding when used appropriately, it’s essential to weigh the potential benefits against any potential risks.
  • Medical history: Inform your doctor about any history of skin infections, allergies, or other medical conditions, as well as any previous adverse reactions to corticosteroids or other medications.
  • Follow-up appointments: Regularly follow up with your doctor to monitor your response to Topicort LP and adjust treatment as needed. They may also assess for any potential side effects or complications.

Always use Topicort LP exactly as prescribed by your healthcare provider and adhere to their instructions and recommendations for safe and effective use. If you have any questions or concerns about using Topicort LP, do not hesitate to discuss them with your doctor or pharmacist.

What special dietary instructions should I follow?

Regarding special dietary instructions, there are generally no specific dietary restrictions associated with the use of Topicort LP. However, maintaining a balanced diet and staying well-hydrated can support overall skin health and may complement the treatment of skin conditions. If you have any concerns or specific dietary considerations, it’s advisable to discuss them with your healthcare provider.

What should I do if I forget a dose?

If you forget to apply a dose of Topicort LP, apply it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not apply extra medication to make up for a missed dose. Using more than the prescribed amount can increase the risk of side effects. If you have any questions or concerns about missed doses, consult your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Topicort LP (desoximetasone), like other topical corticosteroids, may cause side effects, although not everyone experiences them. Common side effects may include:

  • Skin irritation: This can manifest as burning, stinging, itching, or redness at the application site.
  • Skin thinning: Long-term or excessive use of Topicort LP may lead to thinning of the skin, especially in areas where the medication is applied frequently or in large amounts.
  • Skin discoloration: Prolonged use of corticosteroids may cause changes in skin pigmentation, such as lightening or darkening of the skin.
  • Stretch marks: Topical corticosteroids can sometimes contribute to the development of stretch marks, particularly in areas where the skin is thin, such as the groin or armpits.
  • Acne or folliculitis: Some individuals may experience acne or inflammation of hair follicles (folliculitis) in the areas where Topicort LP is applied.
  • Allergic reactions: While rare, allergic reactions to topical corticosteroids like desoximetasone can occur, leading to symptoms such as rash, hives, swelling, or difficulty breathing. Seek medical attention immediately if you experience any signs of an allergic reaction.
  • Delayed wound healing: In some cases, prolonged use of corticosteroids may delay wound healing, particularly if applied to open wounds or broken skin.
  • Systemic effects: Although less common with topical corticosteroids compared to systemic administration, some absorption of the medication into the bloodstream can occur, potentially leading to systemic side effects such as adrenal suppression, Cushing’s syndrome, or elevated blood sugar levels, especially with long-term or extensive use.

It’s important to use Topicort LP as directed by your healthcare provider and to report any persistent or bothersome side effects. If you experience severe skin irritation, signs of infection at the application site, or any other concerning symptoms, contact your doctor for further evaluation and guidance. They may recommend adjusting your treatment regimen or discontinuing the medication if necessary.

What should I know about storage and disposal of this medication?

Storage and disposal of Topicort LP:


  • Store Topicort LP at room temperature away from moisture and heat.
  • Keep the medication out of reach of children and pets.
  • Do not freeze Topicort LP.


  • Dispose of Topicort LP according to local regulations or guidelines.
  • Do not flush medications down the toilet or pour them into a drain unless instructed to do so.
  • If you have unused or expired medication, consult with your pharmacist or local waste disposal facility on how to safely dispose of it.

In case of emergency/overdose

  • In case of accidental ingestion of Topicort LP or overdose, contact your local poison control center (1-800-222-1222 in the United States) or seek emergency medical attention immediately.
  • If topical corticosteroids like desoximetasone are ingested or applied excessively, it can lead to systemic effects such as adrenal suppression, so prompt medical evaluation is essential.

What other information should I know?

  • Follow your healthcare provider’s instructions regarding the use of Topicort LP, including dosage, frequency of application, and duration of treatment.
  • Do not share Topicort LP with others, even if they have similar symptoms, as it may not be suitable for their condition.
  • Inform your doctor about any other medications, supplements, or herbal products you are taking, as they may interact with Topicort LP.
  • Attend regular follow-up appointments with your healthcare provider to monitor your response to treatment and address any concerns or questions you may have.
  • Avoid exposure to sunlight or artificial UV rays (such as tanning beds) while using Topicort LP, as it may increase the risk of skin sensitivity or sunburn.
  • If you experience any new or worsening symptoms while using Topicort LP, such as skin irritation, rash, or infection, contact your doctor for further evaluation and management.

By following these guidelines and communicating openly with your healthcare provider, you can ensure safe and effective use of Topicort LP for the treatment of your skin condition.

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