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Tija (Generic Phenazopyridine)

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Why is this medication prescribed?

Phenazopyridine is a medication primarily prescribed to relieve symptoms associated with urinary tract infections (UTIs) or other urinary tract disorders. It works by providing relief from pain, burning, discomfort, and urgency caused by irritation of the urinary tract mucosa.

How should this medicine be used?

Here’s how Phenazopyridine is typically used:

  • Dosage: The usual adult dosage is 200 mg three times a day, after meals. However, dosages may vary depending on the severity of symptoms and the individual’s response to the medication. It’s important to follow the dosage instructions provided by your healthcare provider.
  • Duration of Use: Phenazopyridine is usually prescribed for short-term use to relieve acute symptoms. It is not typically used for more than two days unless directed by a healthcare professional.
  • Administration: Phenazopyridine is taken orally, usually in tablet or capsule form, with or after meals to minimize stomach upset. It’s important to swallow the tablets whole and not crush or chew them.
  • Hydration: It’s essential to drink plenty of fluids while taking Phenazopyridine to help flush out the urinary tract and promote healing.
  • Monitoring: While Phenazopyridine can provide relief from urinary discomfort, it does not treat the underlying infection. Therefore, it’s important to continue any prescribed antibiotics or other medications as directed by your healthcare provider.
  • Caution: Phenazopyridine can cause urine and other bodily fluids to become orange or reddish in color. This is a normal and harmless effect of the medication. However, it can stain clothing and contact lenses, so be cautious.
  • Consultation: Always consult with your healthcare provider before starting or stopping any medication, including Phenazopyridine. They can provide personalized advice based on your medical history and current health condition.

It’s crucial to note that Phenazopyridine provides symptomatic relief but does not treat the underlying cause of urinary discomfort. Therefore, it’s essential to seek appropriate medical treatment, such as antibiotics for UTIs, to address the root cause of the symptoms.

Other uses for this medicine

Some potential off-label uses of Phenazopyridine include:

  • Interstitial Cystitis (IC): Phenazopyridine may be prescribed off-label to alleviate symptoms of IC, a chronic bladder condition characterized by pelvic pain, urinary frequency, and urgency.
  • Urethritis: In some cases, Phenazopyridine may be used off-label to relieve discomfort associated with urethritis, inflammation of the urethra.
  • Prostate Conditions: It may also be used off-label to help alleviate symptoms of prostate conditions such as prostatitis, which can cause urinary discomfort.
  • Post-Surgical Urinary Symptoms: Phenazopyridine may be used off-label to manage urinary discomfort following certain surgical procedures involving the urinary tract.

What special precautions should I follow?

When using Phenazopyridine, it’s important to follow special precautions to ensure safe and effective use. Here are some precautions to keep in mind:

  • Allergic Reactions: Inform your healthcare provider if you have a history of allergic reactions to Phenazopyridine or any other medications. Allergic reactions may include rash, itching, swelling, severe dizziness, or difficulty breathing.
  • Pregnancy and Breastfeeding: If you are pregnant or breastfeeding, consult your healthcare provider before using Phenazopyridine. While it is generally considered safe during pregnancy, it’s essential to weigh the potential benefits against any risks to the fetus or nursing infant.
  • Renal Impairment: If you have kidney disease or impairment, your healthcare provider may need to adjust your dosage of Phenazopyridine. This medication is primarily excreted through the kidneys, so reduced kidney function can affect its elimination from the body.
  • Liver Impairment: Similarly, if you have liver disease or impairment, your healthcare provider may need to adjust your dosage of Phenazopyridine. Liver impairment can affect the metabolism of the medication.
  • Interaction with Other Medications: Phenazopyridine may interact with certain medications, including sulfa antibiotics. Inform your healthcare provider about all prescription, over-the-counter, and herbal medications you are taking to avoid potential interactions.
  • Caution with Certain Conditions: Use Phenazopyridine with caution if you have certain conditions such as glucose-6-phosphate dehydrogenase (G6PD) deficiency, as it may cause hemolytic anemia in susceptible individuals.

Always follow your healthcare provider’s instructions and guidance when using Phenazopyridine, and report any adverse effects or concerns promptly.

What special dietary instructions should I follow?

Regarding dietary instructions, there are no specific dietary restrictions associated with Phenazopyridine. However, it’s always a good idea to maintain a healthy and balanced diet to support overall health and well-being.

What should I do if I forget a dose?

If you forget to take a dose of Phenazopyridine, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one. If you have any concerns or questions about missed doses, consult your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Phenazopyridine, like any medication, can cause side effects. Common side effects associated with Phenazopyridine include:

  • Orange or Reddish Urine: Phenazopyridine can cause urine and other bodily fluids to become orange or reddish in color. This is a normal and harmless effect of the medication.
  • Stomach Upset: Some people may experience stomach upset, nausea, or vomiting while taking Phenazopyridine, especially if it is not taken with food.
  • Headache: Headaches are a common side effect reported by some individuals taking Phenazopyridine.
  • Dizziness: Phenazopyridine may cause dizziness or lightheadedness, especially when standing up quickly from a sitting or lying position.
  • Skin Discoloration: Rarely, Phenazopyridine may cause skin discoloration or yellowing. This side effect usually resolves once the medication is discontinued.
  • Allergic Reactions: Although rare, some individuals may experience allergic reactions to Phenazopyridine, including rash, itching, swelling, severe dizziness, or difficulty breathing. Seek immediate medical attention if you experience any signs of an allergic reaction.
  • Hemolytic Anemia: In individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency, Phenazopyridine may cause hemolytic anemia. This is a rare but serious side effect that requires immediate medical attention.
  • Other: Other less common side effects of Phenazopyridine may include fever, confusion, and shortness of breath. If you experience any unusual or severe side effects while taking Phenazopyridine, contact your healthcare provider.

It’s important to note that this is not a complete list of side effects associated with Phenazopyridine. If you have concerns about potential side effects or experience any symptoms that are bothersome or persistent while taking Phenazopyridine, it’s essential to consult your healthcare provider for further evaluation and guidance.

What should I know about storage and disposal of this medication?

storage and disposal of Phenazopyridine:


  • Room Temperature: Store Phenazopyridine at room temperature away from moisture and heat. Avoid storing it in the bathroom.
  • Keep Out of Reach of Children: Store Phenazopyridine in a secure location out of the reach of children and pets.
  • Original Container: Keep Phenazopyridine in its original container, tightly closed, to protect it from moisture and light.
  • Avoid Pill Splitting: Do not split or crush Phenazopyridine tablets unless instructed to do so by your healthcare provider.


  • Follow Local Guidelines: Dispose of unused or expired Phenazopyridine tablets according to local guidelines or regulations. Do not flush medications down the toilet or pour them down the drain unless specifically instructed to do so.
  • Medication Take-Back Programs: Many communities have medication take-back programs or facilities where you can safely dispose of unused medications. Check with your local pharmacy or law enforcement agency for information on disposal options in your area.

In case of emergency/overdose

  • Seek Medical Help: In case of overdose or emergency, such as accidentally taking too much Phenazopyridine, call your local poison control center at 1-800-222-1222 or seek emergency medical attention immediately.
  • Symptoms of Overdose: Symptoms of Phenazopyridine overdose may include blue or purple coloration of the skin, methemoglobinemia (a condition where oxygen-carrying capacity of the blood is reduced), and possibly other symptoms such as nausea, vomiting, and abdominal pain.

What other information should I know?

  • Follow Directions: Take Phenazopyridine exactly as prescribed by your healthcare provider. Do not take more of it, take it more often, or take it for a longer period than recommended.
  • Complete Course: Finish the entire course of Phenazopyridine as prescribed, even if your symptoms improve before the medication is finished.
  • Monitoring: While taking Phenazopyridine, monitor your symptoms and report any new or worsening symptoms to your healthcare provider.
  • Caution with Certain Conditions: Inform your healthcare provider about any medical conditions you have, especially kidney or liver disease, as adjustments to your Phenazopyridine dosage may be necessary.

Always consult your healthcare provider or pharmacist if you have any questions or concerns about storing, disposing, or using Phenazopyridine, and follow their recommendations for safe and effective use.

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