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Tavalisse (Generic Fostamatinib)

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Why is this medication prescribed?

Tavalisse (fostamatinib) is prescribed to treat chronic immune thrombocytopenia (ITP) in certain adults and pediatric patients aged 1 year and older who have not responded well to other treatments. ITP is a condition characterized by a low platelet count in the blood, which can lead to an increased risk of bleeding.

Platelets are crucial for blood clotting, and when their numbers are reduced, it can result in easy bruising, petechiae (small red or purple dots on the skin), and bleeding, both externally and internally. Tavalisse works by inhibiting an enzyme involved in the destruction of platelets, helping to increase platelet counts and reduce the risk of bleeding.

How should this medicine be used?

Here are some general guidelines on how Tavalisse is typically used:

  • Dosage: The recommended dosage of Tavalisse may vary depending on individual patient factors. It is important to follow the dosage prescribed by the healthcare provider.
  • Administration: Tavalisse is an oral medication, usually taken twice daily with or without food.
  • Monitoring: Regular monitoring of platelet counts is essential during treatment to assess the effectiveness of Tavalisse. Adjustments to the dosage may be made based on the patient’s response and platelet count.
  • Duration of Treatment: The duration of Tavalisse treatment will be determined by the healthcare provider based on the patient’s response to the medication.
  • Compliance: It is crucial for patients to take Tavalisse as prescribed and to follow up with their healthcare provider regularly. Missing doses or stopping the medication without consulting a healthcare professional could affect the treatment’s efficacy.

It’s important to note that these are general guidelines, and individual patient circumstances may vary. Patients should always follow their healthcare provider’s instructions and seek clarification on any questions or concerns they may have about their treatment with Tavalisse.

Other uses for this medicine

Tavalisse (fostamatinib) is primarily indicated for the treatment of chronic immune thrombocytopenia (ITP). It is important to consult with a healthcare professional for the most up-to-date information on medication uses and precautions.

What special precautions should I follow?

As for special precautions when using Tavalisse, here are some general guidelines:

  • Allergies: Inform your healthcare provider of any known allergies or sensitivities to fostamatinib or any other medications.
  • Medical History: Provide a comprehensive medical history to your healthcare provider, including any history of liver problems, high blood pressure, bleeding disorders, or other significant health issues.
  • Pregnancy and Breastfeeding: It is essential to discuss the potential risks and benefits of using Tavalisse during pregnancy or while breastfeeding. The decision to use this medication should be made in consultation with a healthcare professional.
  • Liver Function: Tavalisse may affect liver function, so regular monitoring of liver enzymes is typically recommended during treatment. If you have liver disease or experience symptoms such as yellowing of the eyes or skin (jaundice), dark urine, or persistent nausea, inform your healthcare provider promptly.
  • Drug Interactions: Inform your healthcare provider about all medications, including prescription and over-the-counter drugs, as well as dietary supplements, that you are taking. Certain medications may interact with Tavalisse, potentially affecting its efficacy or increasing the risk of side effects.
  • Vaccinations: Discuss with your healthcare provider whether any vaccinations are needed before starting Tavalisse, as certain live vaccines may pose a risk during treatment.
  • Blood Pressure Monitoring: Tavalisse may cause an increase in blood pressure. Regular monitoring of blood pressure is usually recommended, and adjustments to antihypertensive medications may be necessary.

It’s crucial to follow your healthcare provider’s instructions and attend all scheduled appointments for monitoring during Tavalisse treatment. If you have any concerns or experience unusual side effects, contact your healthcare provider promptly. Always consult with a healthcare professional for personalized advice based on your specific medical situation.

What special dietary instructions should I follow?

As of last update, there were no specific dietary restrictions associated with Tavalisse. However, it’s important to maintain a balanced and healthy diet, as nutrition plays a crucial role in overall health.

What should I do if I forget a dose?

If you forget to take a dose of Tavalisse, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Tavalisse (fostamatinib) may cause side effects, and it’s important to be aware of them and promptly notify your healthcare provider if you experience any unusual symptoms. Not everyone will experience these side effects, and the severity can vary from person to person. Common side effects of Tavalisse include:

  • Diarrhea: Diarrhea is one of the most common side effects of Tavalisse. It’s important to stay hydrated if you experience diarrhea, and your healthcare provider may adjust your dosage if it becomes severe.
  • Hypertension (High Blood Pressure): Tavalisse can lead to an increase in blood pressure. Regular monitoring of blood pressure is typically recommended during treatment.
  • Elevated Liver Enzymes: Tavalisse may affect liver function, leading to elevated liver enzymes. Regular liver function tests are often conducted during treatment.
  • Nausea: Some individuals may experience nausea as a side effect of Tavalisse.
  • Abdominal Pain: Abdominal pain or discomfort may occur in some individuals.
  • Headache: Headaches have been reported as a side effect of Tavalisse.
  • Respiratory Infections: Tavalisse may increase the risk of respiratory infections. Inform your healthcare provider if you develop symptoms such as cough, shortness of breath, or persistent sore throat.
  • Dizziness: Some individuals may experience dizziness while taking Tavalisse.
  • Bruising and Bleeding: Since Tavalisse is used to treat a condition (chronic immune thrombocytopenia) characterized by low platelet counts, an increase in bruising and bleeding may be observed in some patients.

It’s important to note that this is not an exhaustive list of side effects, and individual responses to the medication can vary. Serious side effects are possible, so any unexpected or severe symptoms should be reported to your healthcare provider promptly. Additionally, discuss any pre-existing medical conditions or medications you are taking that may interact with Tavalisse with your healthcare provider. Always follow your healthcare provider’s advice and attend scheduled monitoring appointments to ensure your safety during treatment.

What should I know about storage and disposal of this medication?

Storage and Disposal of Tavalisse:

  • Storage: Store Tavalisse at room temperature, away from excessive heat and moisture. Keep the medication in its original container with the lid tightly closed.
  • Disposal: Follow your healthcare provider’s or pharmacist’s instructions on how to dispose of unused Tavalisse. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Proper disposal helps prevent environmental contamination.

In case of emergency/overdose

In the event of a suspected overdose or if you experience severe symptoms, seek emergency medical attention or contact your local poison control center immediately. Overdose symptoms may include severe diarrhea, nausea, vomiting, dizziness, or signs of liver problems.

What other information should I know?

  • Follow Healthcare Provider’s Instructions: Always take Tavalisse exactly as prescribed by your healthcare provider. Do not alter the dosage or stop taking the medication without consulting your healthcare professional.
  • Regular Monitoring: Regular monitoring of blood pressure, liver function, and platelet counts is typically conducted during Tavalisse treatment. Attend all scheduled appointments to ensure proper monitoring.
  • Inform Healthcare Provider: Inform your healthcare provider about all medications, including prescription and over-the-counter drugs, as well as dietary supplements, that you are taking. This helps to identify potential interactions.
  • Pregnancy and Breastfeeding: Discuss with your healthcare provider the potential risks and benefits of using Tavalisse if you are pregnant or breastfeeding. The decision to continue or discontinue the medication will be made based on individual circumstances.
  • Notify Healthcare Provider of Any Changes: Inform your healthcare provider of any changes in your health, including new symptoms or the development of other medical conditions.
  • Attend Follow-Up Appointments: Regular follow-up appointments with your healthcare provider are essential to assess the effectiveness of the treatment and monitor for any potential side effects.
  • Patient Assistance Programs: If you encounter challenges with the cost of Tavalisse, inquire about patient assistance programs or financial assistance options that may be available.

Always consult with your healthcare provider or pharmacist for the most current and personalized information regarding your medication. If you have any concerns or questions, they can provide guidance based on your specific health status and needs.

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