WARNING

Tanzeum (albiglutide) is a medication used to treat type 2 diabetes by helping regulate blood sugar levels. However, like any medication, Tanzeum is not without risks. It’s crucial to consult with a healthcare professional before starting or changing any medication regimen. Here are some potential risks associated with Tanzeum:

• Hypoglycemia: Tanzeum, like other diabetes medications, may cause low blood sugar levels (hypoglycemia). This can lead to symptoms such as dizziness, shakiness, sweating, confusion, and, in severe cases, unconsciousness.
• Gastrointestinal side effects: Some people may experience gastrointestinal issues such as nausea, diarrhea, and abdominal pain while taking Tanzeum. These side effects are generally mild, but individuals should report any persistent or severe symptoms to their healthcare provider.
• Pancreatitis: There have been reports of pancreatitis (inflammation of the pancreas) associated with Tanzeum use. Symptoms may include severe abdominal pain that can radiate to the back. It is essential to seek medical attention promptly if these symptoms occur.
• Hypersensitivity reactions: Some individuals may experience allergic reactions to Tanzeum, such as rash, itching, or swelling. In rare cases, more severe allergic reactions like anaphylaxis may occur, necessitating immediate medical attention.
• Renal impairment: Tanzeum may affect kidney function in some individuals. Patients with pre-existing kidney problems or those at risk for kidney issues should be closely monitored while taking this medication.
• Thyroid tumors: Studies in rodents have shown an increased risk of thyroid tumors with the use of glucagon-like peptide-1 (GLP-1) receptor agonists, the class of drugs to which Tanzeum belongs. However, the relevance of these findings to humans is unclear.

It’s important to note that this is not an exhaustive list of potential risks, and individual responses to medication can vary. Only a healthcare professional can assess your specific health condition, consider your medical history, and determine if Tanzeum is an appropriate and safe treatment for you. Always follow your healthcare provider’s guidance and report any unusual symptoms promptly.

Why is this medication prescribed?

Tanzeum (albiglutide) is prescribed to manage type 2 diabetes. It belongs to a class of medications known as glucagon-like peptide-1 (GLP-1) receptor agonists. Tanzeum helps regulate blood sugar levels by increasing the release of insulin and reducing the amount of glucose produced by the liver.

Tanzeum is prescribed to adults with type 2 diabetes, either as a monotherapy or in combination with other diabetes medications. It is not intended for the treatment of type 1 diabetes or diabetic ketoacidosis.

How should this medicine be used?

Here are some key points about how Tanzeum is typically used:

• Dosage: The dosage of Tanzeum is individualized based on the patient’s needs and response to the medication. It is usually administered once a week.
• Administration Method: Tanzeum is given as a subcutaneous injection (under the skin). It comes in a prefilled pen, and healthcare providers typically provide instructions on how to self-administer the injection.
• Injection Site: The injections are usually given in the abdomen, thigh, or upper arm. The injection site should be rotated to minimize the risk of lipodystrophy (changes in fat tissue).
• Consistency: It is important to take Tanzeum consistently at the same time each week to maintain stable blood sugar control.

Additional Considerations:

• Combination Therapy: Tanzeum is often prescribed alongside other diabetes medications, such as metformin, sulfonylureas, or insulin, depending on the individual’s treatment plan.
• Monitoring: Regular monitoring of blood sugar levels, as well as kidney and liver function, may be necessary while using Tanzeum. Your healthcare provider will determine the appropriate frequency of monitoring.
• Adherence: It’s crucial to adhere to the prescribed dosage and administration schedule. If you miss a dose, it is advisable to take it as soon as possible within five days of the missed dose. If more than five days have passed, skip the missed dose and resume the regular schedule.

It is essential to follow your healthcare provider’s instructions and attend regular check-ups to assess the effectiveness of the treatment and monitor for any potential side effects. Never adjust the dosage or stop taking Tanzeum without consulting your healthcare professional.

Other uses for this medicine

Tanzeum (albiglutide) is primarily used for the treatment of type 2 diabetes. It is a glucagon-like peptide-1 (GLP-1) receptor agonist designed to help regulate blood sugar levels. The information available might not include any new uses or indications that have emerged since then. Always consult with a healthcare professional or check more recent sources for the latest information.

What special precautions should I follow?

Regarding special precautions for Tanzeum, it’s important to note the following:

• Allergies: Inform your healthcare provider if you have allergies to albiglutide or any other ingredients in Tanzeum. Allergic reactions can occur, and it’s crucial to discuss any history of hypersensitivity.
• Pancreatitis: Tanzeum has been associated with an increased risk of pancreatitis. Inform your healthcare provider if you have a history of pancreatitis or if you experience symptoms such as severe abdominal pain, which may require prompt medical attention.
• Thyroid Tumors: Studies in rodents have shown an increased risk of thyroid tumors with GLP-1 receptor agonists. While the relevance to humans is unclear, discuss any thyroid issues with your healthcare provider.
• Kidney Function: Tanzeum may affect kidney function. Individuals with pre-existing kidney problems or those at risk for kidney issues should be monitored closely while using this medication.
• Hypoglycemia: Tanzeum, like other diabetes medications, may lead to low blood sugar levels. Be aware of symptoms such as dizziness, shakiness, and confusion. Ensure that your healthcare provider provides guidance on managing hypoglycemia.
• Medication Interactions: Inform your healthcare provider about all medications, including prescription, over-the-counter, and herbal supplements, that you are taking. Some medications may interact with Tanzeum.
• Pregnancy and Breastfeeding: The safety of Tanzeum during pregnancy and breastfeeding is not well established. Consult with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.
• Injection Site Reactions: As with any injectable medication, there may be injection site reactions. Rotate injection sites to minimize the risk of irritation.

Always follow your healthcare provider’s recommendations and instructions for using Tanzeum. Report any side effects or concerns promptly, and attend regular check-ups to monitor your response to the medication. If you have specific questions or concerns about Tanzeum, it’s best to discuss them with your healthcare provider for personalized advice.

What special dietary instructions should I follow?

Special Dietary Instructions:

• Consistent Diet: Maintain a consistent and balanced diet. Follow any dietary recommendations provided by your healthcare provider or dietitian.
• Alcohol Consumption: Discuss alcohol consumption with your healthcare provider, as alcohol can affect blood sugar levels and may interact with Tanzeum.
• Meal Timing: Depending on your healthcare provider’s recommendations, you may need to coordinate Tanzeum injections with meal timing. Follow any specific instructions provided.

What should I do if I forget a dose?

• Timing: If you miss a dose, take it as soon as possible within five days of the missed dose.
• More Than Five Days: If more than five days have passed since the missed dose, skip it and resume your regular dosing schedule.
• Consult Healthcare Provider: If you have questions or concerns about missed doses, contact your healthcare provider for guidance.

What side effects can this medication cause?

Tanzeum (albiglutide), like any medication, can cause side effects. It’s important to note that not everyone will experience these side effects, and their severity can vary. If you are prescribed Tanzeum, your healthcare provider will weigh the potential benefits against the risks based on your individual health status. Common side effects and less common, but more serious, side effects may include:

Common Side Effects:

• Injection Site Reactions: Redness, swelling, or itching at the injection site is common. Rotating injection sites can help minimize these reactions.
• Gastrointestinal Issues: Mild nausea, diarrhea, and abdominal pain may occur. These symptoms often improve over time.

Less Common but Serious Side Effects:

• Pancreatitis: Symptoms may include severe abdominal pain that may radiate to the back. Seek medical attention promptly if you experience these symptoms.
• Hypoglycemia (Low Blood Sugar): This can occur, especially when Tanzeum is used in combination with other diabetes medications. Symptoms may include dizziness, shakiness, sweating, confusion, and, in severe cases, unconsciousness.
• Allergic Reactions: Allergic reactions such as rash, itching, or swelling of the face, lips, or tongue can occur. Severe allergic reactions (anaphylaxis) are rare but require immediate medical attention.
• Kidney Problems: Tanzeum may affect kidney function, and individuals with pre-existing kidney problems may be at higher risk.
• Thyroid Tumors: Studies in rodents have shown an increased risk of thyroid tumors with GLP-1 receptor agonists, although the relevance to humans is unclear.

It’s essential to report any side effects or concerns to your healthcare provider promptly. They can provide guidance on managing side effects or adjust your treatment plan if necessary. Do not stop taking Tanzeum without consulting your healthcare professional.

This list may not be exhaustive, and individual responses to medication can vary. Always refer to the prescribing information provided by your healthcare provider or the medication package insert for comprehensive details on potential side effects and safety information.

What should I know about storage and disposal of this medication?

Storage and Disposal of Tanzeum:

• Storage: Store Tanzeum in the refrigerator at a temperature between 36°F to 46°F (2°C to 8°C). Do not freeze Tanzeum, and protect it from light.
• Avoid Exposure to High Temperatures: Do not expose Tanzeum to temperatures above 86°F (30°C). If Tanzeum is accidentally exposed to higher temperatures, it should be discarded.
• Keep Out of Reach of Children: Store Tanzeum out of the reach of children and pets.
• Protect from Light: Keep Tanzeum in the original carton to protect it from light.
• Do Not Use Expired Medication: Check the expiration date on the medication package, and do not use Tanzeum if it has expired.
• Disposal: Dispose of used injection pens or prefilled syringes as instructed by your healthcare provider or pharmacist. Follow local regulations for the disposal of medications.

In case of emergency/overdose

• Contact Emergency Services: In case of an emergency or suspected overdose, contact emergency medical services or go to the nearest emergency room.
• Symptoms of Overdose: The symptoms of Tanzeum overdose may include severe nausea, vomiting, and hypoglycemia (low blood sugar). Seek medical attention immediately if you suspect an overdose.

What other information should I know?

• Regular Monitoring: Regularly monitor your blood sugar levels as recommended by your healthcare provider.
• Follow Healthcare Provider’s Instructions: Adhere to your healthcare provider’s instructions regarding the dosage, administration, and dietary recommendations while using Tanzeum.
• Inform Healthcare Providers: Inform all healthcare providers (including dentists and surgeons) about your use of Tanzeum before any medical procedures or surgeries.
• Medical Alert Bracelet: Consider wearing a medical alert bracelet or carrying a medical alert card to inform healthcare providers that you are using Tanzeum.
• Keep Appointments: Attend regular follow-up appointments with your healthcare provider for monitoring and adjustment of your treatment plan.
• Communication: Report any unusual symptoms, side effects, or concerns to your healthcare provider promptly.

Always consult with your healthcare provider or pharmacist for specific guidelines and recommendations related to the storage, disposal, and emergency procedures for Tanzeum. This information is a general guide and may not cover all possible scenarios or individual health situations.