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Risperidone

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WARNING

Risperidone is an antipsychotic medication used to treat conditions such as schizophrenia, bipolar disorder, and certain behavioral problems in children with autism. While it can be effective in managing symptoms, there are potential risks and side effects associated with its use. It’s important to note that individual responses to medication can vary, and the following information is a general overview of potential risks:

  • Extrapyramidal Symptoms (EPS): Risperidone can cause EPS, which include symptoms like tremors, muscle stiffness, restlessness, and tardive dyskinesia (involuntary movements of the face and body).
  • Metabolic Effects: There may be an increased risk of weight gain, high blood sugar levels, and lipid abnormalities. This can contribute to a higher risk of diabetes and cardiovascular issues.
  • Neuroleptic Malignant Syndrome (NMS): Although rare, NMS is a severe and potentially life-threatening condition associated with antipsychotic medications, including risperidone. Symptoms may include high fever, muscle rigidity, altered mental status, and autonomic dysfunction.
  • Hyperprolactinemia: Risperidone can lead to elevated levels of the hormone prolactin, potentially causing side effects such as irregular menstrual periods, breast enlargement, and lactation (even in males).
  • Sedation and Drowsiness: Risperidone can cause drowsiness and sedation, which may affect an individual’s ability to concentrate or operate machinery.
  • Orthostatic Hypotension: Some individuals may experience a drop in blood pressure upon standing, leading to dizziness or fainting.
  • Increased Mortality in Elderly Patients with Dementia: Elderly individuals with dementia-related psychosis treated with antipsychotic drugs, including risperidone, may have an increased risk of death.
  • Allergic Reactions: While rare, allergic reactions to risperidone can occur. Seek medical attention if you experience symptoms such as rash, itching, swelling, severe dizziness, or difficulty breathing.

It’s crucial to discuss any concerns or potential side effects with a healthcare professional before starting or adjusting the dose of risperidone. They can provide personalized advice based on an individual’s medical history and specific circumstances. Additionally, regular monitoring and follow-up appointments are important to assess the medication’s effectiveness and manage any potential side effects.

Why is this medication prescribed?

Risperidone is an antipsychotic medication that is prescribed to treat various mental/mood disorders, including schizophrenia and bipolar disorder. It works by affecting the balance of neurotransmitters (chemicals that transmit signals in the brain) to help alleviate symptoms such as hallucinations, delusions, and disorganized thinking.

Here are some common uses of Risperidone:

  • Schizophrenia: Risperidone is often prescribed to manage symptoms of schizophrenia, including hallucinations, delusions, and thought disorders.
  • Bipolar Disorder: It can be used to treat acute manic or mixed episodes associated with bipolar disorder.
  • Autism Spectrum Disorders: Risperidone may also be prescribed to manage irritability associated with autism spectrum disorders in children and adolescents.
  • Tourette’s Syndrome: In some cases, it may be used to control tics and vocal outbursts associated with Tourette’s syndrome.

How should this medicine be used?

The exact dosage and duration of Risperidone treatment depend on the individual’s condition, medical history, and the prescribing doctor’s assessment. It’s crucial to follow the prescribed dosage and not adjust it without consulting a healthcare professional.

Here are general guidelines on how Risperidone is commonly used:

  • Oral Form: Risperidone is usually taken orally, with or without food. It is typically prescribed once or twice daily.
  • Consistency: It’s important to take Risperidone consistently at the same time each day to maintain a steady level of the medication in the bloodstream.
  • Follow Doctor’s Instructions: Always follow your doctor’s instructions regarding dosage and duration. Do not stop taking Risperidone abruptly without consulting your healthcare provider, as this can lead to withdrawal symptoms.
  • Regular Check-ups: Regular check-ups with the prescribing doctor are important to monitor the medication’s effectiveness and to address any potential side effects or concerns.
  • Missed Dose: If a dose is missed, take it as soon as you remember. However, if it’s almost time for the next scheduled dose, skip the missed dose and continue with the regular dosing schedule.
  • Overdose: In case of an overdose or if you suspect an overdose, seek medical attention immediately. Symptoms may include drowsiness, dizziness, fainting, and irregular heartbeat.

It’s essential to be aware of potential side effects, and any unusual or severe reactions should be reported to your healthcare provider promptly. This information is a general overview, and specific instructions may vary based on individual health circumstances, so it’s crucial to consult with a healthcare professional for personalized advice.

Other uses for this medicine

Some off-label uses of Risperidone may include:

  • Obsessive-Compulsive Disorder (OCD): Risperidone might be prescribed as an adjunctive treatment for individuals with OCD who do not respond well to first-line treatments.
  • Post-Traumatic Stress Disorder (PTSD): In some cases, Risperidone may be used to address symptoms associated with PTSD.
  • Tourette’s Syndrome: Risperidone may be considered for managing tics and other symptoms associated with Tourette’s syndrome.
  • Dementia-Related Behavioral Disturbances: Risperidone might be used cautiously and for a short duration to manage severe behavioral symptoms in individuals with dementia.

What special precautions should I follow?

Regarding special precautions for Risperidone, here are some important considerations:

  • Pregnancy and Breastfeeding: Risperidone may pass into breast milk, and its safety during pregnancy is not well-established. It’s essential to inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.
  • Medical Conditions: Inform your doctor about any pre-existing medical conditions, especially cardiovascular diseases, diabetes, liver problems, and seizures. Risperidone may have interactions or exacerbate certain conditions.
  • Elderly Patients: Elderly individuals with dementia-related psychosis treated with antipsychotic drugs like Risperidone have an increased risk of death. Risperidone should be used with caution in this population.
  • Neuroleptic Malignant Syndrome (NMS): This is a potentially life-threatening condition associated with antipsychotic medications. If you experience symptoms such as high fever, muscle stiffness, confusion, or irregular pulse, seek medical attention immediately.
  • Extrapyramidal Symptoms (EPS): Risperidone may cause EPS, which includes symptoms like tremors, stiffness, and involuntary movements. Report any unusual symptoms to your healthcare provider.
  • Interactions with Other Medications: Inform your healthcare provider about all medications, supplements, and herbal products you are taking, as Risperidone may interact with certain substances.

Always follow your doctor’s advice, attend regular check-ups, and communicate any concerns or side effects promptly. It’s crucial to have a comprehensive discussion with your healthcare provider to ensure that Risperidone is prescribed and used safely based on your individual health needs.

What special dietary instructions should I follow?

Risperidone does not typically require specific dietary restrictions. However, maintaining a healthy and balanced diet is generally advisable for overall well-being. If you have specific concerns about diet and medication interactions, it’s best to discuss them with your healthcare provider or a registered dietitian.

What should I do if I forget a dose?

If you forget to take a dose of Risperidone, follow these general guidelines:

  • Take the Missed Dose as Soon as Possible: If you remember shortly after the missed dose, take it as soon as you remember.
  • Skip the Missed Dose if It’s Almost Time for the Next Dose: If it’s close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
  • Do Not Double Up on Doses: Do not take a double dose to make up for a missed one. This can increase the risk of side effects.
  • Consult Your Healthcare Provider: If you are unsure about what to do or if you miss multiple doses, contact your healthcare provider for guidance.

What side effects can this medication cause?

Risperidone, like any medication, can cause side effects. It’s important to note that not everyone will experience these side effects, and their severity can vary. Common side effects of Risperidone include:

  • Sedation or Drowsiness: Risperidone may cause drowsiness, especially when starting the medication or adjusting the dosage.
  • Weight Gain: Some people may experience weight gain while taking Risperidone. Maintaining a healthy diet and exercise routine is advisable to manage this side effect.
  • Increased Prolactin Levels: Risperidone can lead to elevated levels of prolactin, a hormone that can cause breast enlargement or tenderness, menstrual irregularities, and, in some cases, milk production in both males and females.
  • Movement Disorders (Extrapyramidal Symptoms – EPS): These can include tremors, stiffness, restlessness, and involuntary movements. In some cases, this may lead to a condition called tardive dyskinesia, which involves repetitive, involuntary movements of the face and body.
  • Metabolic Changes: Risperidone may contribute to metabolic changes, such as increased blood sugar levels and lipid abnormalities.
  • Orthostatic Hypotension: This refers to a drop in blood pressure upon standing, which may cause dizziness or lightheadedness.
  • Increased Risk of Diabetes: Risperidone has been associated with an increased risk of diabetes, so monitoring blood sugar levels is important, especially in individuals with pre-existing diabetes or risk factors.
  • Anticholinergic Effects: These can include dry mouth, constipation, blurred vision, and urinary retention.
  • Sleep Disturbances: Risperidone may affect sleep patterns and cause insomnia or other sleep-related issues.
  • Increased Risk of Falls in the Elderly: Elderly individuals may be more susceptible to falls due to sedation, orthostatic hypotension, and movement disorders.

It’s important to contact your healthcare provider if you experience any side effects, especially if they are severe or persistent. Additionally, some side effects, such as EPS or tardive dyskinesia, may require prompt medical attention.

In rare cases, Risperidone may be associated with a serious condition called Neuroleptic Malignant Syndrome (NMS), characterized by symptoms such as high fever, muscle stiffness, confusion, and irregular pulse. If you experience any symptoms suggestive of NMS, seek immediate medical attention.

Always follow your healthcare provider’s guidance, attend regular check-ups, and communicate openly about any concerns or side effects you may be experiencing. It’s important not to stop or adjust the medication without consulting your healthcare provider.

What should I know about storage and disposal of this medication?

Storage and Disposal of Risperidone:

  • Storage: Keep Risperidone in its original packaging at room temperature, away from moisture and heat. Avoid storing it in the bathroom. Follow specific storage instructions provided by your pharmacist or healthcare provider.
  • Disposal: Dispose of Risperidone according to local regulations or your healthcare provider’s instructions. Do not flush medications down the toilet unless instructed to do so. Proper disposal helps prevent environmental contamination and accidental ingestion by others.

In case of emergency/overdose

If you suspect an overdose or experience severe symptoms, seek emergency medical attention immediately. Symptoms of Risperidone overdose may include:

  • Drowsiness or Sedation: Severe drowsiness or sedation beyond the expected side effects.
  • Tachycardia (Fast Heart Rate): A rapid heartbeat.
  • Unresponsiveness: Loss of consciousness or unresponsiveness.
  • Seizures: In some cases, an overdose may lead to seizures.

It’s important to contact emergency services or go to the nearest emergency room if you suspect an overdose. Be prepared to provide information about the amount of medication taken and any symptoms observed.

What other information should I know?

  • Regular Monitoring: Attend regular check-ups with your healthcare provider to monitor the medication’s effectiveness and address any concerns.
  • Avoid Alcohol: Limit or avoid alcohol consumption while taking Risperidone, as it can enhance the sedative effects of the medication.
  • Driving and Operating Machinery: Risperidone may cause drowsiness or impair judgment. Use caution when driving or operating machinery until you know how the medication affects you.
  • Medical Alert: Inform healthcare professionals about your use of Risperidone when receiving medical treatment or in case of emergencies.
  • Follow-up with Healthcare Provider: Report any new or worsening symptoms, side effects, or changes in overall health to your healthcare provider promptly.
  • Medication Interactions: Inform your healthcare provider about all medications, supplements, and herbal products you are taking, as Risperidone may interact with certain substances.

Always follow your healthcare provider’s instructions and advice. If you have any questions or concerns about your medication, do not hesitate to discuss them with your healthcare provider or pharmacist. This information is a general guideline, and specific instructions may vary based on individual health circumstances.

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