PrescriptionGiant is a FREE prescription savings program that can save you up to 75% on your prescriptions with or without insurance!

Ri-Gel II (Generic Simethicone)

Actual product appearance may differ slightly.

Click the CARD below to print or take a screenshot on your mobile phone or tablet. There is no need to download another app!

If you would like to personalize your card enter your full name in the member name field below the card at this link and click the Update button.


Why is this medication prescribed?

Simethicone is not typically prescribed; rather, it is available over-the-counter as an oral medication. Simethicone is an anti-foaming agent used to relieve symptoms of excess gas in the digestive tract, including bloating, discomfort, and flatulence (gas). It works by coalescing small gas bubbles in the stomach and intestines, making them easier to pass. Simethicone is often used to alleviate symptoms associated with conditions like indigestion, heartburn, and irritable bowel syndrome (IBS).

How should this medicine be used?

Simethicone is typically taken orally, and the specific instructions for use may vary depending on the formulation (e.g., tablets, chewable tablets, liquid drops). Here are some general guidelines:

  • Tablets or Capsules: Swallow the tablet or capsule whole with a full glass of water. Follow the recommended dosage instructions provided by your healthcare provider or as indicated on the product packaging.
  • Chewable Tablets: Chew the tablet thoroughly before swallowing. Follow the recommended dosage instructions.
  • Liquid Drops: Measure the appropriate dose using the provided dropper or measuring device. The liquid drops can often be mixed with water or another liquid before ingestion.
  • Timing: Simethicone is typically taken after meals and at bedtime or as directed by a healthcare professional. Follow the recommended frequency of doses.
  • Follow Instructions: Always follow the specific instructions provided by your healthcare provider or on the product packaging. Do not exceed the recommended dosage unless instructed to do so by a healthcare professional.
  • Contact Healthcare Provider: If symptoms persist or worsen despite using simethicone, or if you have any concerns or questions about its use, consult your healthcare provider.

It’s important to note that simethicone is generally well-tolerated, but individual responses may vary. If you have any underlying health conditions or are taking other medications, it’s advisable to consult with your healthcare provider before using simethicone to ensure that it is safe and appropriate for your specific situation.

Other uses for this medicine

  • Postoperative Abdominal Gas: Simethicone may be used in some cases after abdominal surgery to help alleviate postoperative gas.
  • Barium Enema or Upper GI Series: In some medical procedures, such as barium enemas or upper gastrointestinal (GI) series, simethicone may be given to reduce the formation of gas bubbles that could interfere with imaging.
  • Infant Colic: In some cases, healthcare providers may recommend simethicone drops to help alleviate gas-related discomfort in infants.

What special precautions should I follow?

As for special precautions, here are some important considerations when using simethicone:

  • Allergies: If you are allergic to simethicone or any of the ingredients in the specific product, you should not use it.
  • Medical Conditions: Inform your healthcare provider about any existing medical conditions, especially if you have a history of gastrointestinal blockage or if you are pregnant or breastfeeding.
  • Interactions with Medications: If you are taking other medications, especially those that may interact with simethicone, inform your healthcare provider. Simethicone is not absorbed into the bloodstream, so interactions are minimal, but it’s always best to check.
  • Adverse Reactions: While simethicone is generally considered safe and well-tolerated, some individuals may experience adverse reactions. If you develop any unusual or severe symptoms after taking simethicone, contact your healthcare provider.
  • Age Considerations: Use caution when administering simethicone to infants and young children, and always follow the recommended dosage guidelines for the specific age group.
  • Prolonged Symptoms: If symptoms persist or worsen after using simethicone, consult with your healthcare provider to rule out any underlying issues.

Always follow the specific instructions provided with the simethicone product you are using, and consult with your healthcare provider if you have any concerns or questions about its use. If you experience severe or persistent symptoms, it’s crucial to seek medical attention for a thorough evaluation.

What special dietary instructions should I follow?

There are generally no specific dietary restrictions associated with simethicone. However, if you have dietary concerns or restrictions, consult with your healthcare provider.

What should I do if I forget a dose?

  • If you miss a dose of simethicone, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
  • Do not double up on doses to make up for a missed one.
  • If you are unsure about what to do, contact your healthcare provider or follow the specific instructions provided with the product.

What side effects can this medication cause?

Simethicone is generally well-tolerated and has a low risk of side effects because it is not absorbed into the bloodstream. However, as with any medication, some individuals may experience adverse reactions. Commonly reported side effects of simethicone are mild and transient. These may include:

  • Stool Changes: Simethicone can cause a harmless darkening of the color of the stool. This is a normal and expected effect and is not a cause for concern.
  • Constipation or Diarrhea: Changes in bowel habits, such as constipation or diarrhea, may occur in some individuals. However, these effects are generally mild.
  • Nausea or Vomiting: Some people may experience mild nausea or vomiting.
  • Allergic Reactions: While rare, allergic reactions to simethicone can occur. Seek medical attention if you experience symptoms such as rash, itching, swelling, severe dizziness, or difficulty breathing.

It’s important to note that serious side effects from simethicone are extremely uncommon due to its minimal absorption into the bloodstream. If you experience any unusual or severe symptoms after taking simethicone, contact your healthcare provider promptly.

If you have any pre-existing medical conditions or are taking other medications, it’s advisable to consult with your healthcare provider before using simethicone to ensure there are no potential interactions or contraindications.

As always, follow the recommended dosage and usage instructions provided with the specific simethicone product you are using. If you have concerns about potential side effects, consult with your healthcare provider for personalized advice.

What should I know about storage and disposal of this medication?

Storage and Disposal of Simethicone:

  • Storage: Store simethicone products at room temperature, away from moisture and direct sunlight. Follow any specific storage instructions provided with the product.
  • Keep Out of Reach of Children: Store simethicone in a location that is inaccessible to children to prevent accidental ingestion.
  • Disposal: Dispose of simethicone products according to local regulations or guidelines. Do not flush medications down the toilet unless specifically instructed to do so.

In case of emergency/overdose

In the case of a suspected overdose or emergency, contact your local poison control center (in the United States, call 1-800-222-1222) or seek emergency medical attention immediately.

What other information should I know?

  • Follow Instructions: Always follow the specific dosage and usage instructions provided with the simethicone product you are using.
  • Inform Healthcare Provider: Inform your healthcare provider about any other medications you are taking, especially if you are on multiple medications.
  • Allergies: If you are allergic to simethicone or any of the ingredients in the product, do not use it.
  • Consult Healthcare Provider: If you have underlying medical conditions or concerns about the use of simethicone, consult your healthcare provider for personalized advice.
  • Pregnancy and Breastfeeding: If you are pregnant or breastfeeding, consult your healthcare provider before using simethicone to ensure its safety for you and your baby.
  • Follow-up with Healthcare Provider: If symptoms persist or worsen, or if you have any concerns about the use of simethicone, follow up with your healthcare provider.
  • Read Product Information: Read and understand all information provided with the simethicone product, including any warnings, precautions, and possible side effects.

Remember that simethicone is generally considered safe when used as directed, and serious side effects are rare due to its minimal absorption into the bloodstream. However, if you have any questions or concerns, it’s always best to consult with your healthcare provider for guidance.

Copyright © 2023 PrescriptionGiant.com