WARNING

Ravulizumab-cwvz is a medication used to treat certain blood disorders, specifically paroxysmal nocturnal hemoglobinuria (PNH). As with any medication, there are potential risks and side effects associated with Ravulizumab-cwvz. It’s important to note that the information provided here is general, and individual responses to the medication can vary. Always consult with a healthcare professional for personalized advice.

Common side effects of Ravulizumab-cwvz may include:

• Headache
• Upper respiratory tract infections
• Pain in the extremities
• Nausea

Serious risks and potential adverse reactions may include:

• Meningococcal infections: Ravulizumab-cwvz increases the risk of serious and potentially fatal meningococcal infections. Patients are usually vaccinated against meningococcal infections before starting treatment, but they should remain vigilant for symptoms such as headache, fever, and neck stiffness.
• Hypersensitivity reactions: Some individuals may experience allergic reactions to Ravulizumab-cwvz. Symptoms can range from mild to severe and may include rash, itching, and difficulty breathing.
• Risk of serious infections: Ravulizumab-cwvz may increase the susceptibility to other infections. Patients should report any signs of infection, such as fever or persistent sore throat, to their healthcare provider.
• Increased risk of high blood pressure: Blood pressure should be monitored regularly during treatment with Ravulizumab-cwvz.

It’s crucial to discuss any concerns or potential side effects with your healthcare provider before starting Ravulizumab-cwvz. They can provide more detailed information based on your medical history and help weigh the potential benefits against the risks.

Why is this medication prescribed?

Ravulizumab-cwvz is a medication prescribed for the treatment of paroxysmal nocturnal hemoglobinuria (PNH), a rare and serious blood disorder. PNH is characterized by the destruction of red blood cells, leading to symptoms such as fatigue, shortness of breath, and an increased risk of blood clots.

Ravulizumab-cwvz belongs to a class of drugs known as complement inhibitors. It works by inhibiting the activity of the complement system, a part of the immune system that, when overactivated, can contribute to the destruction of red blood cells in individuals with PNH.

How should this medicine be used?

Ravulizumab-cwvz is a medication used to treat certain blood disorders, such as paroxysmal nocturnal hemoglobinuria (PNH). It is administered as an injection and is typically given by a healthcare professional. The specific instructions for using Ravulizumab-cwvz can vary, so it’s essential to follow your doctor’s recommendations and the instructions provided with the medication. Here are some general guidelines:

• Administration: Ravulizumab-cwvz is administered intravenously (IV), meaning it is injected directly into a vein. This is usually done in a healthcare setting such as a hospital or clinic.
• Dosage: The dosage and frequency of Ravulizumab-cwvz injections will be determined by your healthcare provider based on your individual medical condition. It’s crucial to adhere to the prescribed dosage and schedule.
• Preparation: The healthcare professional will prepare the medication for injection. It may come in a vial or pre-filled syringe.
• Infusion Time: The injection is given as an infusion, which means it is slowly administered over a specific period. The infusion time may vary, but it is typically given over several hours. The slow infusion helps reduce the risk of infusion reactions.
• Monitoring: During the infusion, healthcare providers will monitor you for any potential side effects or reactions. This close monitoring is standard for many IV medications.
• Follow-Up: After the infusion, your healthcare provider may schedule regular follow-up appointments to monitor your response to the medication, assess your condition, and make any necessary adjustments to the treatment plan.

Always follow your healthcare provider’s instructions precisely. If you have any questions or concerns about the administration of Ravulizumab-cwvz, be sure to discuss them with your healthcare team. It’s important to inform your healthcare provider about any other medications you are taking, as well as any allergies or medical conditions you may have. This information will help ensure the safe and effective use of Ravulizumab-cwvz.

Other uses for this medicine

It’s important to note that new uses or indications for medications may have been approved since my last update. Always consult with a healthcare professional or check the latest medical literature for the most current information on medication uses.

What special precautions should I follow?

Regarding special precautions for ravulizumab-cwvz, it’s crucial to discuss your medical history and any existing conditions with your healthcare provider before starting treatment. Here are some general precautions:

• Infections: Ravulizumab-cwvz may increase the risk of serious infections. Inform your healthcare provider if you have a history of infections, and monitor for signs of infection during treatment.
• Meningococcal Infections: The medication may increase the risk of meningococcal infections. Patients are often vaccinated against meningococcal infections before starting treatment with ravulizumab-cwvz.
• Hypersensitivity Reactions: Some individuals may experience hypersensitivity reactions during or after the infusion. Signs of a reaction may include rash, difficulty breathing, or swelling of the face. Healthcare providers are trained to manage these reactions.
• Vaccinations: Depending on your medical history and the specific guidance from your healthcare provider, certain vaccinations may be recommended before starting treatment with ravulizumab-cwvz.
• Liver Function: Ravulizumab-cwvz may affect liver function, so regular monitoring of liver function tests may be necessary during treatment.
• Pregnancy and Breastfeeding: The safety of ravulizumab-cwvz during pregnancy and breastfeeding is not well-established. Discuss with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.

Always follow your healthcare provider’s instructions and inform them of any medications, supplements, or other treatments you are currently taking. If you experience any side effects or have concerns during the course of treatment, promptly communicate with your healthcare team.

As medication information may change over time, it’s essential to consult with your healthcare provider or refer to the most recent prescribing information for ravulizumab-cwvz for the latest and most accurate guidance.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with Ravulizumab-cwvz. However, it’s important to maintain a healthy and balanced diet to support overall well-being, especially if you have specific dietary concerns or conditions. Always follow any dietary advice provided by your healthcare provider.

What should I do if I forget a dose?

If you forget a dose of Ravulizumab-cwvz, contact your healthcare provider or the healthcare facility where you receive your infusions promptly. It’s essential to adhere to the prescribed dosing schedule to ensure the effectiveness of the medication in managing your condition.

What side effects can this medication cause?

Ravulizumab-cwvz, like any medication, can cause side effects. It’s important to note that not everyone will experience these side effects, and some individuals may experience effects that are not listed. Additionally, the severity of side effects can vary from person to person. If you are prescribed Ravulizumab-cwvz, your healthcare provider will closely monitor you for potential side effects. Common and serious side effects of Ravulizumab-cwvz may include:

Common Side Effects:

• Headache
• Upper respiratory tract infections
• Pain in the extremities
• Nausea

Serious Side Effects:

• Meningococcal Infections: Ravulizumab-cwvz increases the risk of serious and potentially fatal meningococcal infections. Patients are usually vaccinated against meningococcal infections before starting treatment, but they should remain vigilant for symptoms such as headache, fever, and neck stiffness.
• Hypersensitivity Reactions: Some individuals may experience allergic reactions to Ravulizumab-cwvz. Symptoms can range from mild to severe and may include rash, itching, and difficulty breathing. Serious allergic reactions may require immediate medical attention.
• Risk of Serious Infections: Ravulizumab-cwvz may increase the risk of serious infections. Patients should report any signs of infection, such as fever or persistent sore throat, to their healthcare provider.
• Increased Risk of High Blood Pressure: Blood pressure should be monitored regularly during treatment with Ravulizumab-cwvz.
• Liver Problems: Elevated liver enzymes have been reported in some patients receiving Ravulizumab-cwvz. Your healthcare provider will monitor your liver function.

It’s crucial to communicate any unusual or severe symptoms to your healthcare provider promptly. This list is not exhaustive, and other side effects may occur. Your healthcare provider will provide detailed information about potential side effects based on your medical history and individual response to the medication.

As the information may have changed since my last update, and individual cases may vary, always rely on the guidance of your healthcare provider and refer to the latest prescribing information for Ravulizumab-cwvz for the most accurate and current details.

What should I know about storage and disposal of this medication?

Storage and Disposal of Ravulizumab-cwvz Injection:

Storage:

• Temperature: Ravulizumab-cwvz is typically stored in a refrigerator at a temperature between 36°F to 46°F (2°C to 8°C). It should not be frozen.
• Protect from Light: Keep the medication in the original carton to protect it from light.
• Do Not Shake: Do not shake the vial; gently invert it if needed to avoid foaming.

Always check the specific storage instructions provided by the manufacturer and your healthcare provider.

Disposal:

Proper disposal of unused or expired medications is important for safety and environmental reasons. Follow any specific disposal instructions provided by your healthcare provider or local regulations. This may involve returning unused medications to a healthcare facility or using a drug take-back program.

In case of emergency/overdose

In case of an emergency or suspected overdose, contact your healthcare provider, local emergency services, or a poison control center immediately. Be prepared to provide information about the medication, the amount taken (if known), and any symptoms experienced.

What other information should I know?

• Regular Monitoring: Regular monitoring of your health, including blood tests and vital signs, may be necessary during treatment with Ravulizumab-cwvz. Attend all scheduled appointments with your healthcare provider.
• Medical Alert: Wear a medical alert bracelet or carry a medical alert card to inform healthcare providers about your treatment with Ravulizumab-cwvz in case of emergencies.
• Follow-up Care: Follow your healthcare provider’s instructions for follow-up care, including any additional medications or treatments that may be part of your overall management plan.
• Informing Healthcare Providers: Inform all healthcare providers involved in your care, including dentists and other specialists, that you are receiving Ravulizumab-cwvz. This is important for coordinated and safe healthcare delivery.

Always consult with your healthcare provider or pharmacist for specific guidance tailored to your individual circumstances. The information provided here is general and may not cover all aspects of your treatment with Ravulizumab-cwvz.