PrescriptionGiant is a FREE prescription savings program that can save you up to 75% on your prescriptions with or without insurance!

Nostrilla Nasal Spray (Generic Oxymetazoline Nasal Spray)

Actual product appearance may differ slightly.

Click the CARD below to print or take a screenshot on your mobile phone or tablet. There is no need to download another app!


If you would like to personalize your card enter your full name in the member name field below the card at this link and click the Update button.

Why is this medication prescribed?

Oxymetazoline nasal spray is commonly prescribed for the temporary relief of nasal congestion or a stuffy nose caused by various conditions such as allergies, sinusitis, or the common cold. It belongs to a class of medications known as nasal decongestants.

The active ingredient in oxymetazoline nasal spray works by constricting the blood vessels in the nasal passages. This constriction reduces the swelling of the nasal tissues, which helps to relieve congestion and improve breathing through the nose. The effects of oxymetazoline typically last for several hours, providing temporary relief from nasal congestion.

How should this medicine be used?

When using oxymetazoline nasal spray, it’s important to follow the instructions provided by your healthcare provider or the product label. Here are general guidelines for using oxymetazoline nasal spray:

  • Blow your nose gently to clear any mucus or debris from your nasal passages before using the nasal spray.
  • Shake the bottle of oxymetazoline nasal spray well to ensure proper mixing of the medication.
  • Remove the protective cap from the nozzle.
  • Tilt your head slightly forward and insert the nozzle into one nostril. Be careful not to insert it too far or block the nostril completely.
  • Close the other nostril by gently pressing it with your finger.
  • While inhaling through your nose, press down on the spray bottle to release the medication. Breathe in gently to ensure the spray reaches the nasal passages.
  • Repeat the process for the other nostril if instructed to do so.
  • After using the nasal spray, tilt your head back slightly for a few seconds to allow the medication to spread within the nasal passages.
  • Avoid blowing your nose immediately after using the nasal spray to allow the medication to take effect.
  • Replace the protective cap on the nozzle to prevent contamination.

Remember to read the instructions specific to your oxymetazoline nasal spray product as different brands may have slightly different instructions. It’s crucial to use the medication only as directed and not exceed the recommended dosage or duration of use. If you have any concerns or questions about how to use oxymetazoline nasal spray, consult your healthcare provider or pharmacist for clarification.

Other uses for this medicine

In addition to its primary use as a nasal decongestant, Oxymetazoline Nasal Spray may have some off-label uses. These uses are not approved by the FDA but may be prescribed or recommended by healthcare professionals in certain circumstances. Some examples of off-label uses for Oxymetazoline Nasal Spray include:

  • Nasal congestion associated with allergies, such as allergic rhinitis.
  • Eustachian tube dysfunction, which can cause ear congestion and pressure.
  • Nasal congestion related to sinusitis or sinus infections.
  • Preoperative or postoperative nasal decongestion in certain surgical procedures.

What special precautions should I follow?

Regarding special precautions, here are a few important points to consider when using oxymetazoline nasal spray:

  • Duration of use: Oxymetazoline nasal spray is intended for short-term use, usually no longer than three to five days. Prolonged or excessive use can lead to rebound congestion. If your symptoms persist beyond the recommended usage period, consult a healthcare professional.
  • Age restrictions: Some oxymetazoline nasal sprays may not be suitable for children below a certain age. It’s essential to follow the age recommendations provided by your healthcare provider or the product label.
  • Medical conditions: Inform your healthcare provider if you have any medical conditions, particularly heart disease, high blood pressure, diabetes, thyroid problems, or any other chronic medical condition. They can assess whether oxymetazoline nasal spray is safe for you to use.
  • Drug interactions: Discuss any other medications, including prescription, over-the-counter, or herbal supplements, that you are currently taking with your healthcare provider. Certain medications, such as MAO inhibitors and other nasal decongestants, may interact with oxymetazoline nasal spray and cause adverse effects.
  • Pregnancy and breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before using oxymetazoline nasal spray. They can provide guidance on its safety and potential risks.
  • Side effects: Like any medication, oxymetazoline nasal spray can cause side effects. Common side effects include temporary burning, stinging, or dryness of the nose. If you experience severe or persistent side effects, contact your healthcare provider.

Always follow the instructions and advice provided by your healthcare provider or the product label to ensure safe and effective use of oxymetazoline nasal spray.

What special dietary instructions should I follow?

There are no specific dietary instructions to follow for oxymetazoline nasal spray. However, it’s generally recommended to maintain a healthy and balanced diet while using any medication to support overall well-being.

What should I do if I forget a dose?

If you forget a dose of oxymetazoline nasal spray, simply take the missed dose as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

What side effects can this medication cause?

Oxymetazoline nasal spray, like any medication, can cause side effects. Not everyone will experience these side effects, and their severity can vary from person to person. Common side effects of oxymetazoline nasal spray may include:

  • Temporary burning or stinging sensation in the nose
  • Dryness or irritation of the nasal passages
  • Sneezing
  • Increased nasal discharge
  • Nausea
  • Headache
  • Dizziness
  • Increased blood pressure (rare, but more likely with excessive or prolonged use)

These side effects are generally mild and temporary, and they usually improve as your body adjusts to the medication. However, if you experience severe or persistent side effects, or if you develop any allergic reactions such as rash, itching, swelling, or difficulty breathing, it’s important to seek medical attention immediately.

It’s worth noting that prolonged or excessive use of oxymetazoline nasal spray can lead to a condition called rebound congestion. Rebound congestion occurs when the nasal passages become even more congested when the medication wears off. To avoid this, it’s essential to follow the recommended duration of use and dosage instructions provided by your healthcare provider or the product label.

If you have any concerns about the side effects of oxymetazoline nasal spray or if you experience any unexpected symptoms while using the medication, consult your healthcare provider for further evaluation and guidance.

What should I know about storage and disposal of this medication?

Storage and disposal of Oxymetazoline nasal spray:

  • Store the nasal spray at room temperature, away from direct sunlight and heat sources.
  • Keep it out of the reach of children.
  • Do not freeze the nasal spray.
  • Do not use the spray after the expiration date printed on the bottle.
  • If you no longer need the medication or if it has expired, follow appropriate disposal guidelines. You can ask your pharmacist or local waste disposal authority about the proper disposal methods for your area.

In case of emergency/overdose

  • In case of an emergency or accidental overdose, contact emergency services or your local poison control center immediately.
  • Symptoms of overdose may include severe headache, dizziness, tremors, fast or irregular heartbeat, high blood pressure, difficulty breathing, and seizures.
  • It is important to use the medication as directed and avoid exceeding the recommended dose.

What other information should I know?

  • Oxymetazoline nasal spray is intended for nasal use only. Avoid contact with eyes, mouth, or open wounds.
  • Do not use the nasal spray for longer than 3 consecutive days unless directed by a healthcare professional. Prolonged use may lead to rebound congestion.
  • Inform your healthcare provider about any existing medical conditions, such as high blood pressure, heart disease, diabetes, thyroid problems, or prostate issues.
  • Discuss with your healthcare provider or pharmacist if you are taking any other medications to ensure there are no potential drug interactions.

Remember, it’s essential to follow the instructions provided by your healthcare provider or the medication’s packaging. If you have any concerns or questions, consult your healthcare professional or pharmacist for personalized advice.

Copyright © 2023