WARNING

Nilandron (nilutamide) is a medication primarily used in the treatment of prostate cancer. While it can be effective in managing the condition, it is important to be aware of the potential risks and side effects associated with its use. Here are some of the risks of taking Nilandron:

• Liver problems: Nilandron can cause liver damage, leading to symptoms such as yellowing of the skin or eyes (jaundice), dark urine, abdominal pain, or persistent nausea. Regular monitoring of liver function is essential during treatment.
• Lung problems: Rarely, Nilandron may cause lung disorders, including interstitial pneumonitis, which can cause breathing difficulties, cough, or fever. If any respiratory symptoms occur, medical attention should be sought immediately.
• Vision changes: Some individuals may experience visual disturbances while taking Nilandron, such as blurred vision or difficulty distinguishing colors. If any changes in vision occur, it is important to inform your healthcare provider.
• Gastrointestinal effects: Nilandron can cause gastrointestinal side effects like nausea, vomiting, diarrhea, or loss of appetite. It is advisable to report severe or persistent symptoms to your doctor.
• Allergic reactions: In rare cases, allergic reactions to Nilandron may occur, resulting in symptoms like rash, itching, swelling, or difficulty breathing. Seek immediate medical assistance if an allergic reaction is suspected.
• Sexual dysfunction: Nilandron may cause sexual side effects, including decreased libido, erectile dysfunction, or breast enlargement in males. Discuss any concerns with your healthcare provider.
• Other common side effects: Additional common side effects of Nilandron include fatigue, hot flashes, increased sweating, dizziness, or headache.

It is crucial to discuss the potential risks and benefits of Nilandron with your healthcare provider before starting treatment. They can provide personalized advice, monitor your progress, and address any concerns you may have.

Why is this medication prescribed?

Nilandron (nilutamide) is prescribed for the treatment of advanced prostate cancer, particularly in cases where the cancer has spread to other parts of the body. It belongs to a class of medications called antiandrogens, which work by blocking the effects of male hormones (androgens) on the prostate cancer cells.

How should this medicine be used?

The recommended dosage and usage of Nilandron should be determined by your healthcare provider, and it is important to follow their instructions carefully. Generally, Nilandron is taken orally as tablets, usually once daily. It is typically prescribed in combination with other treatments, such as a luteinizing hormone-releasing hormone (LHRH) analog or surgical castration.

Here are some key points to remember when using Nilandron:

• Timing: Take Nilandron at the same time each day to maintain a consistent level of the medication in your body.
• Swallowing: Swallow the tablets whole with a glass of water. Do not crush, chew, or break the tablets unless advised by your doctor.
• Food: Nilandron should be taken after a meal to minimize stomach upset.
• Duration: Continue taking Nilandron for the prescribed duration, even if you start feeling better. Do not stop the medication without consulting your healthcare provider.
• Missed dose: If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for the missed one.

It is essential to communicate with your healthcare provider about any questions, concerns, or side effects you experience while using Nilandron. They can provide personalized guidance, monitor your progress, and make any necessary adjustments to your treatment plan.

Other uses for this medicine

Nilandron (nilutamide) is primarily prescribed for the treatment of advanced prostate cancer. However, there may be other off-label or investigational uses for Nilandron that are not yet approved by regulatory authorities. It is important to note that using a medication for off-label purposes should only be done under the guidance of a qualified healthcare professional.

What special precautions should I follow?

As for special precautions when using Nilandron, here are some important considerations:

• Allergies: Inform your healthcare provider if you have any known allergies to Nilandron or any of its components. This medication may contain inactive ingredients that can cause allergic reactions or other problems.
• Liver function: Nilandron can potentially cause liver damage. It is crucial to have regular liver function tests before and during treatment to monitor any changes. If you have pre-existing liver disease or a history of liver problems, inform your doctor before starting Nilandron.
• Lung function: Nilandron has been associated with lung disorders, including interstitial pneumonitis. If you experience symptoms such as shortness of breath, cough, or fever, seek immediate medical attention.
• Vision changes: Nilandron can cause visual disturbances, including blurred vision or difficulty distinguishing colors. If you notice any changes in your vision, inform your doctor promptly.
• Coagulation disorders: Nilandron may have an anticoagulant effect, meaning it can increase the risk of bleeding. Inform your healthcare provider if you have a bleeding disorder or if you are taking medications that affect blood clotting.
• Pregnancy and breastfeeding: Nilandron should not be used by women, especially during pregnancy or while breastfeeding, as it can potentially harm the unborn child or nursing infant. This medication is intended for use in men with prostate cancer.
• Other medications and supplements: Inform your healthcare provider about all the medications, supplements, and herbal products you are taking, as Nilandron may interact with certain substances and affect their effectiveness or increase the risk of side effects.
• Driving and operating machinery: Nilandron may cause dizziness or drowsiness. If you experience these effects, avoid driving or operating machinery until you know how the medication affects you.

It is crucial to discuss your medical history, current medications, and any specific concerns with your healthcare provider before starting Nilandron. They can provide you with the necessary information, precautions, and personalized guidance for safe and effective use of the medication.

What special dietary instructions should I follow?

When taking Nilandron (nilutamide), there are no specific dietary restrictions that need to be followed. However, it is generally recommended to take Nilandron after a meal to minimize stomach upset. It is important to maintain a balanced and healthy diet as advised by your healthcare provider, particularly if you are undergoing cancer treatment.

What should I do if I forget a dose?

If you forget to take a dose of Nilandron, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can increase the risk of side effects.

What side effects can this medication cause?

Nilandron (nilutamide) may cause various side effects in individuals taking the medication. It’s important to note that not everyone experiences side effects, and the severity and occurrence of side effects can vary from person to person. Here are some potential side effects associated with Nilandron:

• Gastrointestinal Effects: Nausea, vomiting, diarrhea, and loss of appetite are common side effects of Nilandron. These symptoms are usually mild and can be managed with supportive care or adjustments to the dosing schedule.
• Liver Problems: Nilandron can potentially cause liver damage. Symptoms of liver problems may include yellowing of the skin or eyes (jaundice), dark urine, abdominal pain, or persistent nausea. Regular monitoring of liver function is necessary during treatment.
• Respiratory Issues: Although rare, Nilandron has been associated with lung disorders, including interstitial pneumonitis. Symptoms may include shortness of breath, cough, or fever. If respiratory symptoms occur, seek immediate medical attention.
• Vision Changes: Some individuals may experience vision changes while taking Nilandron, such as blurred vision or difficulty distinguishing colors. If any changes in vision occur, it is important to inform your healthcare provider.
• Sexual Dysfunction: Nilandron can cause sexual side effects, including decreased libido and erectile dysfunction. In some cases, males may also experience breast enlargement (gynecomastia). Discuss any concerns with your healthcare provider.
• Fatigue and Hot Flashes: Fatigue and hot flashes are common side effects associated with Nilandron. These symptoms may vary in intensity and can be managed through lifestyle adjustments and support.
• Other Common Side Effects: Additional side effects that may occur include increased sweating, dizziness, headache, abdominal pain, skin rash, or itching.

It is important to report any side effects to your healthcare provider, as they can provide guidance on managing or alleviating these effects. They can also evaluate the severity of the side effects and determine if any adjustments to your treatment plan are necessary.

What should I know about storage and disposal of this medication?

• Storage: Keep Nilandron tablets in their original container at room temperature, away from excessive heat, moisture, and direct light. Follow any specific storage instructions provided by your pharmacist or healthcare provider.
• Keep out of reach of children and pets: Nilandron should be stored in a secure location to prevent accidental ingestion by children or pets.
• Disposal: Properly dispose of unused or expired Nilandron tablets in accordance with local regulations or guidelines. Do not flush medications down the toilet or drain unless instructed to do so. Consult your pharmacist or local waste disposal authority for guidance on the safe disposal of medications.

In case of emergency/overdose

In case of emergency or suspected overdose, contact your local emergency services or go to the nearest emergency room immediately. It is helpful to have the original container or packaging of the medication with you, as it provides important information for healthcare professionals.

What other information should I know?

• Regular check-ups: Attend scheduled appointments with your healthcare provider for monitoring and evaluation of your condition during Nilandron treatment. This allows them to assess the effectiveness of the medication and monitor for any potential side effects.
• Drug interactions: Inform your healthcare provider about all medications, supplements, and herbal products you are taking, as they can interact with Nilandron and affect its effectiveness or increase the risk of side effects.
• Laboratory tests: Nilandron may affect certain laboratory tests, including liver function tests. Inform the healthcare professional conducting the tests that you are taking Nilandron.
• Compliance: Take Nilandron as prescribed by your healthcare provider and follow their instructions carefully. Do not stop or change the dosage of the medication without consulting your healthcare provider.
• Supportive care: Engage in a healthy lifestyle, including a balanced diet, regular exercise, and getting enough rest. Seek support from healthcare professionals, support groups, or counseling services if needed.

Always consult your healthcare provider or pharmacist for specific and personalized information regarding the use, storage, and disposal of Nilandron. They can provide detailed instructions based on your individual circumstances.