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Why is this medication prescribed?

Nabilone is a medication that is prescribed for several medical purposes. It is a synthetic cannabinoid with properties similar to THC (tetrahydrocannabinol), the primary psychoactive component of cannabis. Nabilone is primarily prescribed for two main reasons:

  • Nausea and vomiting associated with chemotherapy: Nabilone is commonly used to manage chemotherapy-induced nausea and vomiting, especially when other antiemetic medications have been ineffective. It helps reduce nausea and vomiting by interacting with the cannabinoid receptors in the central nervous system.
  • Chronic pain management: Nabilone may also be prescribed for the management of chronic pain that has not responded well to other conventional treatments. It can help alleviate pain by affecting the endocannabinoid system, which is involved in regulating pain perception.

How should this medicine be used?

Regarding special precautions for Nabilone, the following points should be considered:

  • Pregnancy and breastfeeding: Nabilone should be used with caution during pregnancy and breastfeeding, as its safety in these situations has not been well established. The potential risks and benefits should be discussed with a healthcare provider.
  • Mental health conditions: Nabilone can have psychiatric side effects, including mood changes, hallucinations, and paranoia. It should be used cautiously in individuals with a history of psychiatric disorders, such as schizophrenia or bipolar disorder.
  • Substance abuse: Nabilone has the potential for abuse and dependence. It should be used cautiously in individuals with a history of substance abuse or addiction.
  • Driving and operating machinery: Nabilone may cause drowsiness, dizziness, or impair cognitive function. It is important to assess how the medication affects you before engaging in activities that require alertness or coordination.
  • Drug interactions: Nabilone may interact with other medications, including sedatives, antidepressants, and anticoagulants. Inform your healthcare provider about all the medications you are taking to avoid potential interactions.

Always consult with your healthcare provider for personalized advice and guidance regarding the use of Nabilone, as precautions may vary depending on individual circumstances and medical history.

Other uses for this medicine

In addition to its primary use for chemotherapy-induced nausea and vomiting, Nabilone may have other off-label uses. Nabilone may be effective in managing chronic pain, particularly neuropathic pain. However, it’s important to note that off-label use should only be pursued under the guidance and supervision of a qualified healthcare provider.

What special precautions should I follow?

As for special precautions when using Nabilone, the following considerations should be kept in mind:

  • Medical history: Inform your healthcare provider about any past or existing medical conditions, especially if you have a history of heart problems, mental health disorders, substance abuse, or liver or kidney disease.
  • Drug interactions: Nabilone may interact with other medications, including sedatives, antidepressants, antipsychotics, and certain antibiotics. It is crucial to disclose all the medications, supplements, and herbal products you are taking to your healthcare provider to avoid potential interactions.
  • Substance abuse: Nabilone has the potential for abuse and addiction. Individuals with a history of substance abuse or addiction should use Nabilone with caution and under close medical supervision.
  • Pregnancy and breastfeeding: The safety of Nabilone during pregnancy and breastfeeding has not been established. It is important to consult with a healthcare professional to weigh the potential risks and benefits in these situations.
  • Driving and operating machinery: Nabilone can cause drowsiness, dizziness, and impair cognitive function. It is advisable to avoid driving or operating heavy machinery until you know how Nabilone affects you personally.

Always follow the instructions provided by your healthcare provider and read the medication’s accompanying information leaflet for specific precautions and guidance related to Nabilone.

What special dietary instructions should I follow?

There are no specific dietary instructions associated with the use of Nabilone. However, it is generally recommended to follow a balanced and healthy diet while taking any medication. Maintaining a nutritious diet can support your overall health and well-being.

What should I do if I forget a dose?

If you forget to take a dose of Nabilone, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

What side effects can this medication cause?

Nabilone is a synthetic cannabinoid that is primarily used for the treatment of nausea and vomiting associated with chemotherapy, as well as for the management of pain in certain medical conditions. Like any medication, Nabilone can cause side effects. Here are some of the common side effects associated with Nabilone:

  • Dizziness: Nabilone can cause drowsiness and dizziness, which can impair coordination and affect activities that require alertness, such as driving or operating machinery.
  • Dry mouth: Nabilone can cause dryness of the mouth, which may lead to increased thirst and discomfort.
  • Euphoria: Nabilone can produce a feeling of euphoria or a sense of well-being, which may be desirable for some patients but can also lead to abuse or dependence in susceptible individuals.
  • Sedation: Nabilone can have sedative effects, causing drowsiness and sleepiness.
  • Impaired cognitive function: Some individuals may experience difficulties with concentration, memory, or judgment while taking Nabilone.
  • Increased heart rate: Nabilone can cause an increase in heart rate, which may be of concern for individuals with cardiovascular conditions.
  • Psychiatric effects: Nabilone has been associated with psychiatric side effects such as anxiety, paranoia, hallucinations, and disorientation, although these side effects are relatively rare.
  • Orthostatic hypotension: Nabilone can cause a drop in blood pressure upon standing up, resulting in dizziness or lightheadedness.
  • Gastrointestinal effects: Nabilone may cause gastrointestinal symptoms such as nausea, vomiting, or abdominal discomfort.
  • Visual disturbances: Some individuals may experience visual changes, including blurred vision or difficulty focusing.

It’s important to note that not everyone will experience these side effects, and the severity and occurrence of side effects can vary among individuals. It’s always advisable to consult with a healthcare professional for more information about the potential side effects of Nabilone and to discuss any concerns you may have.

What should I know about storage and disposal of this medication?


  • Follow the storage instructions provided by your pharmacist or on the medication label. Typically, Nabilone should be stored at room temperature, away from excessive heat, moisture, and direct sunlight.
  • Keep the medication out of reach of children and pets to prevent accidental ingestion.


  • It is important to dispose of medications properly to prevent them from being used by others or harming the environment.
  • Follow any specific disposal instructions provided by your healthcare provider or local guidelines. If no specific instructions are given, you can check with your local pharmacy or waste management authorities for proper disposal methods.
  • Do not flush Nabilone down the toilet or pour it down the drain unless specifically instructed to do so.

In case of emergency/overdose

  • If you suspect an overdose or experience severe symptoms, such as difficulty breathing, loss of consciousness, or uncontrollable movements, call emergency services immediately (e.g., 911 in the United States) or seek immediate medical attention.
  • Contact your local poison control center or emergency department for guidance on what to do in case of an overdose or accidental ingestion.

What other information should I know?

  • Nabilone may have the potential for abuse or dependence. Store it securely and use it only as prescribed by your healthcare provider.
  • Inform all healthcare professionals involved in your care that you are taking Nabilone, including doctors, dentists, and pharmacists. This helps ensure they have a complete understanding of your medication regimen.
  • Attend regular follow-up appointments with your healthcare provider to monitor your response to Nabilone and address any concerns or side effects.
  • Inform your healthcare provider about all other medications, supplements, or herbal products you are taking, as they can interact with Nabilone.
  • Avoid consuming alcohol while taking Nabilone, as it can increase the risk of side effects such as drowsiness and dizziness.

Always consult your healthcare provider or pharmacist for specific instructions and additional information related to the storage, disposal, emergencies, or any other concerns you may have regarding Nabilone.

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