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Mycolog-II Cream (Generic Nystatin Topical)

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Why is this medication prescribed?

Mycolog-II Cream is a medication used to treat various skin conditions, particularly those caused by fungal and certain bacterial infections. It is a combination of two active ingredients: nystatin and triamcinolone acetonide.

  • Nystatin: This is an antifungal medication that is effective against certain types of fungal infections, including candidiasis (yeast infections).
  • Triamcinolone acetonide: This is a corticosteroid, which helps to reduce inflammation and relieve itching and redness associated with skin conditions.

Mycolog-II Cream is typically prescribed for the treatment of dermatoses (skin disorders) that are complicated by secondary fungal or bacterial infections. Some of the common conditions it may be used for include:

  • Athlete’s foot (tinea pedis)
  • Jock itch (tinea cruris)
  • Ringworm (tinea corporis)
  • Diaper rash (if complicated by fungal infection)
  • Eczema or dermatitis with a secondary fungal or bacterial infection

How should this medicine be used?

Here are some general guidelines for the use of Mycolog-II Cream:

  • Follow the doctor’s instructions: Always use the cream exactly as prescribed by your healthcare provider. The dosage and duration of use may vary depending on the condition being treated and the severity of the infection.
  • Clean and dry the affected area: Before applying the cream, ensure that the affected area is clean and completely dry.
  • Apply a thin layer: Gently apply a thin layer of Mycolog-II Cream to the affected area and the surrounding skin. Avoid getting the cream in your eyes, nose, or mouth.
  • Wash hands after application: After applying the cream, wash your hands thoroughly, unless your hands are the treated area.
  • Avoid bandaging unless instructed: Unless directed by your doctor, you typically should not cover the treated area with a bandage or dressing.
  • Avoid prolonged use: Prolonged use of topical corticosteroids like triamcinolone can lead to skin thinning and other side effects. Follow your doctor’s instructions regarding the duration of treatment.
  • Keep in mind the prescribed duration: Even if your symptoms improve, continue using the cream for the prescribed duration to ensure the infection is completely cleared.
  • Report side effects: If you experience any unusual or severe side effects while using Mycolog-II Cream, contact your healthcare provider immediately.

As with any medication, it’s important to use Mycolog-II Cream only as prescribed and to inform your doctor about any existing medical conditions or medications you may be taking to avoid potential interactions or complications. If you have specific questions or concerns about using this cream, it’s best to consult your healthcare provider for personalized advice.

Other uses for this medicine

Mycolog-II Cream is primarily used for the treatment of skin conditions complicated by fungal or certain bacterial infections, as mentioned in the previous response. However, it’s essential to note that the use of this medication should be strictly based on a doctor’s prescription and guidance. Using Mycolog-II Cream for other purposes without medical supervision is not recommended and may lead to adverse effects or treatment failure.

What special precautions should I follow?

Special precautions to consider when using Mycolog-II Cream:

  • Allergies: Inform your doctor if you have a history of allergies to any of the active ingredients (nystatin or triamcinolone acetonide) or other medications before using Mycolog-II Cream.
  • Pregnancy and breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using this medication with your healthcare provider. The use of topical corticosteroids like triamcinolone during pregnancy should be carefully considered and prescribed only if necessary.
  • Avoid sensitive areas: Do not apply Mycolog-II Cream to the face, groin, underarms, or other sensitive areas unless specifically directed by your doctor. The skin in these areas is more delicate and prone to side effects from prolonged use of corticosteroids.
  • Medical conditions: Inform your doctor about any existing medical conditions you have, especially if you have a history of skin infections, diabetes, or immune system disorders.
  • Interactions: Before using Mycolog-II Cream, provide a list of all medications, vitamins, and herbal supplements you are taking. Certain drugs may interact with the active ingredients in the cream, potentially affecting its effectiveness or increasing the risk of side effects.
  • Avoid contact with eyes: Mycolog-II Cream should not be applied to the eyes or near the eye area. If accidental contact occurs, rinse the eyes thoroughly with water.
  • Discontinue if irritation occurs: If you experience skin irritation, redness, or itching that worsens or persists, discontinue the use of the cream and consult your doctor.
  • Avoid using on open wounds: Mycolog-II Cream should not be used on open wounds or broken skin unless specifically instructed by your doctor.
  • Limit use on children: Use in pediatric patients should be closely monitored and as directed by a healthcare professional, as children are more susceptible to systemic absorption of corticosteroids.

Always follow the prescribed dosage and duration of treatment as advised by your healthcare provider. If you have any concerns or questions about using Mycolog-II Cream, don’t hesitate to consult your doctor for personalized guidance and appropriate medical care.

What special dietary instructions should I follow?

Mycolog-II Cream is a topical medication applied directly to the skin, and there are no specific dietary instructions associated with its use. Since it is not ingested or absorbed systemically, there are no dietary restrictions or requirements that need to be followed while using this cream.

What should I do if I forget a dose?

Regarding what to do if you forget a dose of Mycolog-II Cream, it’s important to note that this medication is typically used on an as-needed basis for skin conditions. It is not used on a strict dosing schedule like oral medications. If you miss an application, simply continue with the next scheduled application as directed by your healthcare provider. Do not try to “catch up” by applying extra cream to make up for the missed dose, as this may lead to excessive use and potential side effects.

What side effects can this medication cause?

Mycolog-II Cream, like any medication, can cause side effects in some individuals. Not everyone will experience side effects, and the severity and frequency of side effects may vary from person to person. It’s important to note that the following list includes common side effects associated with Mycolog-II Cream, but it is not exhaustive. If you experience any unusual or severe reactions while using the cream, contact your healthcare provider immediately.

Common side effects of Mycolog-II Cream may include:

  • Skin irritation: Mild redness, itching, or burning at the application site.
  • Dryness: The skin may become dry or flaky during treatment.
  • Thinning of the skin: Prolonged use of topical corticosteroids like triamcinolone may lead to thinning of the skin, making it more susceptible to injury.
  • Changes in skin pigmentation: Long-term use of corticosteroids on certain areas of the body can cause changes in skin color.
  • Allergic reactions: Rarely, some individuals may experience an allergic reaction to the ingredients in the cream. Symptoms may include hives, rash, swelling, or severe itching.
  • Skin infections: In some cases, the use of Mycolog-II Cream may lead to the development of new skin infections or the worsening of existing infections.
  • Delayed wound healing: Corticosteroids can slow down the healing process of wounds.
  • Acne: Prolonged use on the face or acne-prone areas may trigger or worsen acne.
  • Stretch marks: With prolonged use, corticosteroids can lead to the development of stretch marks (striae) on the skin.
  • Local reactions: The cream should not be applied to areas with open wounds or injuries, as it may cause local irritation or discomfort.

It’s important to use Mycolog-II Cream only as prescribed and for the duration recommended by your healthcare provider. Do not apply the cream to areas other than those specified by your doctor, and avoid using it on sensitive areas like the face, groin, or underarms unless specifically directed.

If you experience any severe or concerning side effects while using Mycolog-II Cream, or if you have any questions about its use, contact your healthcare provider promptly for further evaluation and guidance.

What should I know about storage and disposal of this medication?

Here’s some important information about the storage, disposal, handling of emergencies, and overdose related to Mycolog-II Cream:


  • Store Mycolog-II Cream at room temperature, away from direct sunlight, heat, and moisture.
  • Keep the cream out of reach of children and pets to prevent accidental ingestion.


  • Do not flush Mycolog-II Cream down the toilet or pour it into a drain unless instructed to do so by local waste management authorities.
  • If you need to dispose of the medication, follow the guidelines provided by your healthcare provider or local pharmacy for safe disposal.

In case of emergency/overdose

  • If you accidentally swallow Mycolog-II Cream, contact your local poison control center or seek emergency medical attention immediately.
  • An overdose of topical corticosteroids can lead to systemic effects, especially if large amounts are applied over a large area or if occlusive dressings are used. Symptoms of overdose may include excessive redness, swelling, or thinning of the skin.

What other information should I know

  • Avoid using Mycolog-II Cream for conditions other than those prescribed by your doctor.
  • Inform your healthcare provider about any existing medical conditions, allergies, or medications you are taking before using the cream.
  • If you are using other topical medications or products on the same area where you apply Mycolog-II Cream, consult your doctor or pharmacist to ensure there are no potential interactions.
  • If your symptoms do not improve after using the cream as prescribed or if they worsen, notify your healthcare provider.
  • Follow your doctor’s instructions regarding the duration of treatment. Prolonged use of topical corticosteroids should be avoided unless specifically directed by a healthcare professional.
  • Do not cover the treated area with airtight dressings, bandages, or wraps unless instructed by your healthcare provider.

As with any medication, it’s crucial to use Mycolog-II Cream exactly as prescribed and to follow your doctor’s advice regarding its use and potential side effects. If you have any questions, concerns, or experience any adverse reactions while using the cream, contact your healthcare provider for appropriate guidance and medical care.

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