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Monistat 3 Suppositories (Generic Miconazole Vaginal)

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Why is this medication prescribed?

Monistat 3 Suppositories is a medication used to treat vaginal yeast infections, also known as vaginal candidiasis. Vaginal yeast infections are typically caused by an overgrowth of a type of fungus called Candida. Monistat 3 Suppositories is one of the brand names for a product containing miconazole nitrate, which is an antifungal agent. It is available over-the-counter and is commonly prescribed for the treatment of these infections.

How should this medicine be used?

Here’s how Monistat 3 Suppositories is typically used:

  • Read the Instructions: Before using the product, it’s essential to carefully read the instructions and follow them exactly as directed.
  • Wash Hands and Affected Area: Start by thoroughly washing your hands and the genital area with mild soap and water. Rinse and pat dry with a clean towel.
  • Inserting the Suppository: Most Monistat 3 Suppositories come with an applicator for insertion. If included, use the applicator as directed. If not, you can insert the suppository using your finger. Lie on your back with your knees bent and gently insert the suppository as far into the vagina as comfortably possible. Follow the instructions provided with the product for the correct depth and technique.
  • Dosage: Monistat 3 Suppositories are typically used as a three-day treatment, meaning you insert one suppository each night before bedtime for three consecutive nights. Follow the prescribed regimen recommended by the product or your healthcare provider.
  • Avoid Tampons: During the treatment period, it’s advised to avoid using tampons as they can absorb and reduce the effectiveness of the medication. Use sanitary pads instead.
  • Finish the Treatment: Even if your symptoms improve before the three-day treatment is completed, it’s essential to finish the full course of medication to ensure that the infection is completely cleared.
  • Contact a Healthcare Provider: If your symptoms do not improve or worsen after completing the treatment, or if you experience any severe side effects or allergic reactions, contact your healthcare provider.
  • Preventative Measures: To reduce the risk of future yeast infections, it’s a good idea to maintain good hygiene, avoid wearing tight-fitting clothing, and consider factors like diet and lifestyle that can contribute to yeast overgrowth.

Remember that while Monistat 3 Suppositories can be effective for treating yeast infections, it’s essential to use it as directed and consult with a healthcare provider if you have any doubts or concerns about your symptoms or the treatment. Additionally, if you are pregnant or have other underlying health conditions, it’s advisable to consult with a healthcare professional before using any medication, including over-the-counter products like Monistat.

Other uses for this medicine

Monistat 3 Suppositories are primarily designed and intended for the treatment of vaginal yeast infections (vaginal candidiasis). It contains miconazole nitrate, an antifungal medication, which is specifically formulated to combat fungal overgrowth in the vaginal area. It is not typically used for other purposes, and its use should be restricted to treating yeast infections under the guidance of a healthcare provider or as directed on the product label.

What special precautions should I follow?

Special Precautions for Monistat 3 Suppositories:

  • Consult a Healthcare Provider: Before using Monistat 3 Suppositories, it’s advisable to consult with a healthcare provider, especially if you have never had a vaginal yeast infection before, if you are pregnant, or if you have underlying medical conditions.
  • Allergies and Sensitivities: Inform your healthcare provider if you have a history of allergies or sensitivities to any medications, including antifungal drugs like miconazole.
  • Pregnancy and Breastfeeding: If you are pregnant or breastfeeding, consult your healthcare provider before using Monistat 3 Suppositories. Some antifungal medications may require special consideration during pregnancy or breastfeeding.
  • Other Medications: Discuss with your healthcare provider any other medications you are currently taking, including prescription and over-the-counter drugs, as there may be potential drug interactions.
  • Symptom Persistence: If your symptoms do not improve or worsen after completing the prescribed treatment with Monistat 3 Suppositories, contact your healthcare provider for further evaluation.
  • Use as Directed: Follow the instructions on the product label or those provided by your healthcare provider precisely. Do not use more or less of the medication or use it for a longer duration than prescribed.
  • Avoid Sexual Activity: It is generally recommended to avoid sexual activity while using Monistat 3 Suppositories to prevent spreading the infection or causing irritation.
  • Tampon Use: During the treatment period, avoid using tampons, as they can interfere with the medication’s effectiveness. Use sanitary pads instead.
  • Side Effects: Be aware of potential side effects, which can include vaginal itching, burning, or irritation. If you experience severe or bothersome side effects, discontinue use and contact your healthcare provider.
  • Storage: Store Monistat 3 Suppositories at room temperature, away from moisture and direct sunlight, and keep it out of the reach of children.

It’s crucial to use Monistat 3 Suppositories only as directed and to seek guidance from a healthcare provider if you have any questions or concerns about its use or if you experience any unexpected side effects or complications during treatment.

What special dietary instructions should I follow?

There are no specific dietary instructions that you need to follow while using Monistat 3 Suppositories. However, it’s a good idea to maintain a generally healthy diet and lifestyle to support your overall well-being and immune system, which can help prevent future yeast infections.

What should I do if I forget a dose?

  • If you forget to insert a suppository, try to insert it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
  • Do not use a double dose to make up for a missed one, as this can increase the risk of side effects.

What side effects can this medication cause?

Monistat 3 Suppositories, like any medication, can potentially cause side effects in some individuals. Not everyone will experience side effects, and for many people, the medication is well-tolerated. Common side effects of Monistat 3 Suppositories may include:

  • Vaginal Irritation: Some individuals may experience mild vaginal itching, burning, or irritation after using Monistat 3 Suppositories. This is a relatively common side effect and is usually temporary.
  • Abdominal Pain or Discomfort: In some cases, individuals may experience mild abdominal pain or discomfort.
  • Headache: A headache is another possible side effect, although it is less common.
  • Skin Rash or Hives: Skin reactions such as a rash or hives may occur in rare cases. If you develop a skin rash or hives after using Monistat 3 Suppositories, discontinue use and consult a healthcare provider.
  • Allergic Reactions: While rare, some individuals may have an allergic reaction to the medication. Symptoms of an allergic reaction can include difficulty breathing, swelling of the face, lips, tongue, or throat, and severe itching. Seek immediate medical attention if you experience any signs of an allergic reaction.

It’s important to note that serious side effects are rare with Monistat 3 Suppositories. Most people tolerate the medication well. If you experience severe or persistent side effects or if your symptoms worsen after using the medication, it’s advisable to discontinue use and consult your healthcare provider for further evaluation and guidance.

Additionally, if you have a history of allergies or sensitivity to medications, it’s a good idea to inform your healthcare provider or pharmacist before using Monistat 3 Suppositories, as this may help identify potential risks or interactions.

As with any medication, it’s essential to use Monistat 3 Suppositories as directed by your healthcare provider or according to the product’s label, and to seek medical advice if you have any concerns or questions about its use or potential side effects.

What should I know about storage and disposal of this medication?


  • Room Temperature: Store Monistat 3 Suppositories at room temperature, away from excessive heat or moisture. Avoid exposure to direct sunlight.
  • Keep Out of Reach of Children: Ensure that the medication is stored in a place that is inaccessible to children and pets.
  • Properly Seal the Packaging: Keep the suppositories in their original packaging or container to maintain their integrity and prevent contamination.


  • Dispose Properly: When you have completed your treatment course or if the medication has reached its expiration date, dispose of any remaining suppositories properly.
  • Follow Local Guidelines: Follow your local guidelines for the disposal of over-the-counter medications. Some communities have specific programs or recommendations for medication disposal, while others may suggest throwing them away in the household trash.
  • Do Not Flush: Do not flush Monistat 3 Suppositories down the toilet unless specifically instructed to do so by the product label or your healthcare provider.

In case of emergency/overdose

If you suspect an overdose of Monistat 3 Suppositories, seek immediate medical attention or contact a poison control center. Overdose symptoms may include severe vaginal irritation, burning, itching, or other severe reactions.

What other information should I know

  • Complete the Full Course: It’s essential to complete the full three-day course of treatment as directed by your healthcare provider or as indicated on the product label. Even if your symptoms improve before the treatment is completed, do not stop prematurely.
  • Avoid Sexual Activity: During the treatment period, it’s generally advisable to avoid sexual activity, as the medication may weaken latex condoms and diaphragms, potentially reducing their effectiveness.
  • Follow Instructions Carefully: Always follow the instructions provided with Monistat 3 Suppositories precisely. If you have any questions or concerns about the product or its use, consult your healthcare provider or pharmacist for guidance.
  • Consult a Healthcare Provider: If your symptoms do not improve within a few days after completing the treatment or if they worsen, contact your healthcare provider. They can provide further evaluation and guidance.

Remember that Monistat 3 Suppositories are for vaginal use only and are specifically intended to treat vaginal yeast infections. Do not use this medication for any other purpose unless directed to do so by a healthcare provider. If you have any doubts or questions about the medication, its use, or its potential interactions with other medications, consult with a healthcare professional or pharmacist for personalized advice.

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