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Midamor (Generic Amiloride )

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Why is this medication prescribed?

Midamor is a brand name medication that contains the active ingredient amiloride. It is typically prescribed for the following medical conditions:

  • Hypertension (High Blood Pressure): Midamor is often prescribed to help lower blood pressure in individuals with high blood pressure. It works by reducing the amount of sodium reabsorbed by the kidneys, which leads to increased urine production and decreased fluid retention, ultimately lowering blood pressure.
  • Edema (Fluid Retention): Midamor may also be used to treat edema (fluid retention) that can occur in various conditions, such as congestive heart failure, cirrhosis of the liver, and nephrotic syndrome. By promoting the excretion of excess sodium and water from the body, Midamor can help reduce swelling and fluid buildup.

It’s important to note that Midamor is typically prescribed in combination with other medications, such as diuretics or antihypertensive drugs, as part of a comprehensive treatment plan for these conditions.

How should this medicine be used?

As for how Midamor should be used, you should follow your healthcare provider’s instructions and the medication label carefully. Here are some general guidelines:

  • Dosage: The usual recommended dose of Midamor for hypertension is typically 5 to 10 mg once daily. For edema, the dosage may vary and is determined by your doctor based on your specific condition and response to treatment.
  • Take as Directed: Always take Midamor exactly as prescribed by your healthcare provider. Do not take more or less of it, and do not stop taking it without your doctor’s approval, even if you feel better.
  • Timing: Midamor can be taken with or without food. However, taking it with food may help reduce the risk of stomach upset.
  • Regular Monitoring: Your doctor may need to monitor your blood pressure and electrolyte levels while you are taking Midamor, especially if you are also taking other medications that affect electrolyte balance.
  • Stay Hydrated: Make sure to drink plenty of fluids while taking Midamor, as it can increase urine production, potentially leading to dehydration if you do not replace lost fluids.
  • Side Effects: Be aware of potential side effects, including dizziness, headache, stomach upset, and increased urination. If you experience any severe or unusual side effects, contact your healthcare provider.
  • Drug Interactions: Inform your healthcare provider about all the medications, supplements, and herbal products you are taking, as Midamor may interact with other drugs.

Remember that Midamor should only be used under the supervision and guidance of a qualified healthcare professional. If you have any questions or concerns about its use, consult your healthcare provider for personalized advice.

Other uses for this medicine

Midamor’s primary use is for the treatment of hypertension and conditions characterized by excessive salt and water retention. However, in some cases, it may be used off-label (i.e., not FDA-approved) for other purposes, such as:

  • Edema: It may be used to manage edema (fluid retention) associated with conditions like congestive heart failure, cirrhosis of the liver, or certain kidney disorders.
  • Nephrogenic Diabetes Insipidus: In some cases, Midamor may be used to treat nephrogenic diabetes insipidus, a condition where the kidneys cannot conserve water properly.

What special precautions should I follow?

Special Precautions for Midamor Use:

  • Kidney Function: Prior to starting Midamor, your healthcare provider will evaluate your kidney function. This medication is primarily eliminated by the kidneys, so it should be used cautiously in individuals with impaired kidney function.
  • Potassium Levels: Midamor can cause an increase in potassium levels in the blood (hyperkalemia). Your healthcare provider will monitor your potassium levels regularly. It is essential not to take potassium supplements or consume foods high in potassium without your doctor’s approval while taking Midamor.
  • Salt Intake: You may need to adjust your dietary salt intake while taking Midamor. Your healthcare provider will provide guidance on salt restriction if necessary.
  • Dehydration: Midamor increases urine production, which can lead to dehydration if you don’t drink enough fluids. Make sure to stay adequately hydrated, especially in hot weather or during physical activity.
  • Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using Midamor with your healthcare provider. It may not be suitable for use in some cases.
  • Drug Interactions: Midamor may interact with other medications, including certain diuretics, potassium supplements, nonsteroidal anti-inflammatory drugs (NSAIDs), and others. Inform your healthcare provider of all medications you are taking to avoid potential interactions.
  • Allergies and Sensitivities: If you have known allergies or sensitivities to amiloride or similar medications, inform your healthcare provider.

Always follow your healthcare provider’s instructions and guidance when using Midamor or any prescription medication. If you have questions or experience any side effects, contact your healthcare provider for assistance and advice.

What special dietary instructions should I follow?

  • Potassium-rich Foods: Since Midamor helps maintain potassium levels, it’s important to be cautious with your dietary potassium intake. Foods high in potassium include bananas, oranges, tomatoes, potatoes, spinach, and many other fruits and vegetables. Consult with your doctor or a registered dietitian for guidance on managing your potassium intake.
  • Salt Intake: Midamor is often used in combination with other medications to reduce blood pressure. Reducing your salt (sodium) intake can help these medications work more effectively. Avoid high-sodium foods like processed and canned foods, fast food, and excessive table salt.

What should I do if I forget a dose?

If you forget to take a dose of Midamor, follow these general guidelines:

  • Take It When You Remember: If you remember within a few hours of the missed dose, take it as soon as possible.
  • Skip It If Close to Next Dose: If it’s close to the time for your next scheduled dose, skip the missed dose and take your next dose as usual.
  • Do Not Double Dose: Do not take two doses at the same time to make up for the missed dose. This can increase the risk of side effects.
  • Consult Your Healthcare Provider: If you’re unsure about what to do or if you frequently miss doses, contact your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Midamor (amiloride) is generally considered a well-tolerated medication, but like all medications, it can potentially cause side effects in some individuals. Not everyone will experience these side effects, and their severity can vary from person to person. It’s important to take Midamor under the supervision of a healthcare provider who can monitor your response to the medication. Common side effects of Midamor may include:

  • Nausea and Vomiting: Some people may experience mild nausea or vomiting when taking Midamor.
  • Stomach Upset: This medication can occasionally cause stomach discomfort or cramps.
  • Diarrhea: Diarrhea is another gastrointestinal side effect that can occur.
  • Dizziness: Midamor may lead to dizziness, particularly when standing up quickly. This is more common in the initial stages of treatment.
  • Headache: Headaches can occur as a side effect of Midamor use.
  • Weakness or Fatigue: Some individuals may feel weak or tired while taking this medication.
  • Increased Urination: Midamor is a diuretic, so an increase in urination is expected. However, excessive urination or changes in urine color or frequency should be reported to a healthcare provider.
  • Elevated Blood Potassium Levels (Hyperkalemia): While Midamor is designed to help the body retain potassium, it can sometimes lead to an excessive buildup of potassium in the blood (hyperkalemia). Symptoms of hyperkalemia can include muscle weakness, irregular heartbeat, and numbness or tingling.
  • Allergic Reactions: In rare cases, individuals may experience allergic reactions to Midamor, which can include skin rash, itching, swelling, severe dizziness, and difficulty breathing. Seek immediate medical attention if you suspect an allergic reaction.
  • Electrolyte Imbalances: Midamor can affect electrolyte balance, so it’s important for your healthcare provider to monitor your blood electrolyte levels regularly.

It’s crucial to contact your healthcare provider if you experience any severe or persistent side effects while taking Midamor. Additionally, inform your healthcare provider of all medications, supplements, and herbal products you are taking to minimize the risk of drug interactions.

Keep in mind that your healthcare provider has prescribed this medication because they have determined that the potential benefits outweigh the risks of side effects. It’s important to take the medication as directed and to attend follow-up appointments to monitor your progress and adjust the treatment plan as needed. If you have concerns or questions about Midamor or its side effects, don’t hesitate to discuss them with your healthcare provider.

What should I know about storage and disposal of this medication?

Storage and Disposal:

  • Store Midamor at room temperature, away from moisture, heat, and light. Follow the storage instructions on the medication label.
  • Keep the medication out of reach of children and pets.
  • Do not use Midamor if it has expired or if you no longer need it. Properly dispose of any unused or expired medication.
  • Do not flush Midamor down the toilet or pour it down the drain. Ask your pharmacist or follow local regulations for proper disposal.
  • If you have any questions about the storage or disposal of Midamor, consult your healthcare provider or pharmacist.

In case of emergency/overdose

If you suspect an overdose or experience severe symptoms after taking Midamor, seek immediate medical attention or contact a poison control center at 1-800-222-1222. An overdose of Midamor, or any medication, can be life-threatening. Signs of an overdose may include:

  • Severe dizziness or lightheadedness
  • Irregular or rapid heartbeat
  • Muscle weakness
  • Confusion
  • Nausea and vomiting
  • Weakness or numbness
  • Unconsciousness or loss of consciousness

What other information should I know

  • Follow Prescribed Dosage: Take Midamor exactly as prescribed by your healthcare provider. Do not change the dosage or stop taking it without their approval.
  • Regular Monitoring: Your healthcare provider may perform periodic checks, including blood pressure and electrolyte level measurements, to monitor the medication’s effects and your overall health.
  • Drug Interactions: Inform your healthcare provider of all medications, supplements, and herbal products you are taking, as Midamor can interact with other drugs.
  • Medical Conditions: Inform your healthcare provider about any medical conditions you have, including kidney problems, heart conditions, or allergies, as this can affect the safety and efficacy of Midamor.
  • Dietary Instructions: Follow any dietary recommendations provided by your healthcare provider, particularly related to sodium and potassium intake.
  • Regular Appointments: Attend all follow-up appointments with your healthcare provider to assess your progress and adjust your treatment plan as needed.
  • Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using Midamor with your healthcare provider.

Always keep your healthcare provider informed about any issues or concerns related to your medication. They can provide guidance and address any questions you may have about your treatment with Midamor.

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