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Metronidazole Vaginal

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Why is this medication prescribed?

Metronidazole vaginal gel is a medication prescribed for the treatment of bacterial vaginosis, a common vaginal infection. Bacterial vaginosis occurs when there is an imbalance in the natural bacteria that normally reside in the vagina, leading to an overgrowth of harmful bacteria. Metronidazole is effective in treating this condition because it has antibacterial properties that can help eliminate the overgrowth of harmful bacteria in the vagina.

How should this medicine be used?

Here are some general guidelines on how Metronidazole vaginal gel is typically used:

  • Prescription: You will need a prescription from a healthcare provider to obtain Metronidazole vaginal gel. It is important to consult with a healthcare professional to confirm the diagnosis of bacterial vaginosis and to receive the appropriate treatment.
  • Dosage: The dosage and duration of treatment can vary depending on the specific instructions given by your healthcare provider. Typically, Metronidazole vaginal gel is applied once daily for a certain number of days, such as 5 days.
  • Application: To use the gel, you should follow these steps:
    • Wash your hands thoroughly before handling the applicator and gel.
    • Lie on your back with your knees bent and feet flat on the floor, or you can stand with one foot on a chair or stool.
    • Gently insert the applicator into your vagina as far as it will comfortably go.
    • Squeeze the prescribed amount of gel from the applicator into the vagina.
    • Remove the applicator and discard it according to the manufacturer’s instructions.
  • Avoid sexual intercourse: It’s typically recommended to avoid sexual intercourse during the treatment period, as Metronidazole may weaken latex condoms and diaphragms, making them less effective for birth control.
  • Complete the full course: Even if your symptoms improve before you finish the prescribed course of treatment, it’s essential to complete the entire treatment regimen to ensure the infection is fully cleared.
  • Follow-up: Your healthcare provider may schedule a follow-up appointment to ensure that the infection has been successfully treated and to address any concerns or lingering symptoms.
  • Side effects: While Metronidazole vaginal gel is generally well-tolerated, it can cause side effects like vaginal irritation, itching, and a metallic taste in the mouth. If you experience severe or unusual side effects, contact your healthcare provider.

It’s crucial to use Metronidazole vaginal gel exactly as prescribed by your healthcare provider and to complete the full course of treatment to effectively treat bacterial vaginosis. If you have any questions or concerns about this medication or its use, consult with your healthcare provider or pharmacist for guidance.

Other uses for this medicine

As for other uses of Metronidazole vaginal, it is primarily intended for the treatment of vaginal bacterial infections. It should not be used for any other purpose without the guidance of a healthcare professional.

What special precautions should I follow?

Special precautions to consider when using Metronidazole vaginal include:

  • Prescription Only: Metronidazole vaginal gel is a prescription medication, so it should only be used under the guidance and supervision of a healthcare provider. Do not use it without a prescription, and follow your healthcare provider’s instructions carefully.
  • Allergies and Sensitivities: Inform your healthcare provider if you are allergic to metronidazole or any other medications. Also, let them know if you have a history of allergies or sensitivities to other drugs or substances.
  • Pregnancy and Breastfeeding: Discuss with your healthcare provider the use of Metronidazole vaginal gel if you are pregnant, planning to become pregnant, or breastfeeding. They will weigh the potential risks and benefits and provide guidance accordingly.
  • Medical Conditions: Inform your healthcare provider about any medical conditions you have, especially if you have a history of blood disorders, liver disease, or nerve disorders. These conditions may require special considerations when using metronidazole.
  • Medication Interactions: Tell your healthcare provider about all the medications, supplements, and herbal products you are currently taking. Metronidazole can interact with certain drugs, potentially affecting their effectiveness or increasing the risk of side effects.
  • Alcohol: Avoid consuming alcohol while using Metronidazole vaginal gel and for at least 24 hours after completing the treatment. Combining alcohol with metronidazole can lead to severe nausea, vomiting, and headaches.
  • Side Effects: Be aware of potential side effects, which can include vaginal irritation, itching, a metallic taste in the mouth, and nausea. If you experience severe or persistent side effects, contact your healthcare provider.
  • Sexual Activity: It is advisable to avoid sexual intercourse during the treatment period, as Metronidazole can weaken latex condoms and diaphragms, reducing their effectiveness for contraception.
  • Follow-up: Attend any follow-up appointments as scheduled by your healthcare provider to ensure the infection has cleared and to address any concerns.
  • Storage: Store Metronidazole vaginal gel according to the manufacturer’s instructions, typically at room temperature, away from moisture and heat.

Remember that these precautions are general guidelines, and individual circumstances may vary. Always consult your healthcare provider for specific advice and recommendations tailored to your situation before using Metronidazole vaginal gel or any prescription medication.

What special dietary instructions should I follow?

Dietary Instructions:

  • Alcohol: It is generally advisable to avoid alcohol while taking Metronidazole, as it can cause unpleasant side effects like nausea, vomiting, and a rapid heartbeat when combined with this medication. These effects can be quite severe, so it’s best to abstain from alcohol during your treatment and for at least 48 hours after the last dose.
  • Grapefruit: Although grapefruit is not known to interact directly with Metronidazole Vaginal, it’s always a good practice to consult your healthcare provider about any dietary restrictions or concerns you may have.
  • Other Foods: There are no specific dietary restrictions related to other foods while taking Metronidazole Vaginal. However, it’s important to maintain a healthy diet and stay well-hydrated to support your overall well-being during your treatment.

What should I do if I forget a dose?

If you forget a dose of Metronidazole Vaginal, take it as soon as you remember. However, if it’s close to the time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for a missed one.

What side effects can this medication cause?

Metronidazole vaginal gel or cream is an antibiotic medication used to treat certain vaginal infections. Like all medications, it can cause side effects. Common side effects of Metronidazole vaginal treatment may include:

  • Vaginal Irritation: You may experience mild irritation, burning, itching, or redness in and around the vagina. These symptoms are usually temporary and should improve as you continue treatment.
  • Discharge: Some women may notice an increase in vaginal discharge during treatment. This is often a normal response to the medication and should subside after treatment is completed.
  • Unpleasant Taste: Metronidazole can sometimes cause a metallic or unpleasant taste in the mouth. This is more common when using the oral form of the medication, but it can occur with vaginal gel or cream as well.
  • Nausea: Although less common with vaginal use compared to oral use, some individuals may still experience mild nausea while using Metronidazole vaginal gel or cream.
  • Allergic Reactions: While rare, some people may experience an allergic reaction to Metronidazole. Signs of an allergic reaction may include rash, itching, swelling, severe dizziness, difficulty breathing, or severe dizziness. If you experience any of these symptoms, seek immediate medical attention.
  • Other Side Effects: In rare cases, Metronidazole vaginal treatment may lead to more serious side effects, such as severe vaginal irritation, abdominal pain, or signs of a new infection. If you experience any unusual or severe side effects, contact your healthcare provider promptly.

It’s essential to remember that not everyone will experience side effects, and many people tolerate Metronidazole vaginal treatment well. If you have concerns about side effects or experience any symptoms that worry you during your treatment, don’t hesitate to contact your healthcare provider. They can provide guidance and determine if any adjustments to your treatment are necessary. Additionally, it’s crucial to complete the full course of medication as prescribed by your healthcare provider to effectively treat the infection and reduce the risk of resistance.

What should I know about storage and disposal of this medication?

Regarding storage and disposal, here are some guidelines:


  • Keep out of reach of children: Always store Metronidazole Vaginal and any medication in a place where children cannot access it.
  • Storage temperature: Store the medication at room temperature, away from excessive heat and moisture. Follow the specific storage instructions provided on the medication packaging or by your healthcare provider or pharmacist.
  • Protect from light: Some medications can degrade when exposed to light, so it’s a good practice to store Metronidazole Vaginal in its original packaging or container to protect it from light.


Proper disposal of medication is essential to prevent accidental ingestion and environmental contamination:

  • Do not flush down the toilet: Do not dispose of Metronidazole Vaginal by flushing it down the toilet or pouring it down the drain unless specifically instructed to do so by your healthcare provider or pharmacist.
  • Check local guidelines: Many communities have medication disposal programs or specific instructions for disposing of unused or expired medications. Check with your local pharmacy or healthcare facility for information on safe disposal methods.
  • Use a drug take-back program: If available, take advantage of local drug take-back programs or events to safely dispose of unused or expired medications.
  • In case of emergency/overdose

In case of emergency or suspicion of an overdose, take the following steps:

If you suspect an overdose or experience severe symptoms, seek immediate medical attention or contact a poison control center (in the United States, you can call 1-800-222-1222). Signs of an overdose can include severe nausea, vomiting, loss of coordination, and seizures.

What other information should I know

  • Follow the prescribed course: Take Metronidazole Vaginal for the full course of treatment as prescribed by your healthcare provider, even if your symptoms improve before the medication is finished.
  • Avoid sexual activity during treatment: It’s generally recommended to abstain from sexual activity or use barrier methods (e.g., condoms) while using Metronidazole Vaginal, as it may weaken latex condoms and diaphragms.
  • Inform your healthcare provider: Be sure to inform your healthcare provider about all the medications, supplements, and herbal products you are taking, as some may interact with Metronidazole Vaginal.
  • Follow-up appointments: Attend any follow-up appointments scheduled by your healthcare provider to monitor your progress and ensure the infection has been treated effectively.
  • Complete the treatment: Do not stop taking the medication early, even if your symptoms improve. Prematurely discontinuing the treatment may allow the infection to return or become resistant to the medication.
  • Allergic reactions: If you experience symptoms of an allergic reaction (e.g., rash, itching, swelling, severe dizziness, difficulty breathing), seek immediate medical attention.

Always follow your healthcare provider’s instructions and ask any questions you may have about your medication. They can provide you with specific guidance based on your individual health needs and the prescription provided.

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