PrescriptionGiant is a FREE prescription savings program that can save you up to 75% on your prescriptions with or without insurance!


Actual product appearance may differ slightly.

Click the CARD below to print or take a screenshot on your mobile phone or tablet. There is no need to download another app!

If you would like to personalize your card enter your full name in the member name field below the card at this link and click the Update button.

Why is this medication prescribed?

Methyclothiazide is a medication prescribed primarily to treat high blood pressure (hypertension) and to reduce the swelling (edema) associated with conditions like congestive heart failure and kidney problems. It belongs to a class of drugs called thiazide diuretics, which work by increasing the removal of salt and water from the body through the urine, thereby lowering blood pressure and reducing fluid retention.

How should this medicine be used?

Here are some general guidelines on how Methyclothiazide should be used:

  • Dosage: The specific dosage of Methyclothiazide will vary depending on your medical condition, response to treatment, and your doctor’s recommendations. It is usually taken once daily, preferably in the morning, with or without food.
  • Follow your doctor’s prescription: Always follow your healthcare provider’s instructions and take the medication as prescribed. Do not change the dose or stop taking it without consulting your doctor, as abrupt discontinuation can lead to adverse effects.
  • Swallow the tablet whole: Methyclothiazide is typically available in tablet form. Swallow the tablet whole with a full glass of water. Do not crush or chew the tablet unless your doctor advises otherwise.
  • Take it consistently: To get the most benefit from Methyclothiazide, take it at the same time each day. This will help you remember to take your medication regularly.
  • Stay hydrated: It’s important to drink enough fluids while taking Methyclothiazide to prevent dehydration, as the medication can increase urination. Your doctor will provide guidance on how much fluid you should consume.
  • Monitor your blood pressure: Keep track of your blood pressure as directed by your doctor to ensure that Methyclothiazide is effectively lowering it.
  • Regular check-ups: Your healthcare provider will likely schedule regular check-ups to monitor your blood pressure and overall health while you are taking Methyclothiazide. Be sure to attend these appointments.
  • Inform your doctor: Inform your doctor about any other medications, supplements, or medical conditions you have, as Methyclothiazide can interact with certain drugs and may not be suitable for everyone.
  • Adverse effects: Be aware of potential side effects, such as dizziness, lightheadedness, increased urination, or changes in electrolyte levels (e.g., low potassium levels). If you experience any unusual or severe side effects, contact your healthcare provider.
  • Compliance: To get the maximum benefit from Methyclothiazide, it’s essential to adhere to your treatment plan consistently.

Remember that Methyclothiazide is just one component of a comprehensive treatment plan for high blood pressure or other medical conditions. Lifestyle modifications, such as a balanced diet, regular exercise, and stress management, are also essential for managing these conditions. Always consult with your healthcare provider for personalized guidance and recommendations regarding your specific health needs.

Other uses for this medicine

Methyclothiazide is primarily prescribed for hypertension and fluid retention associated with various medical conditions. Its use is generally not recommended for other purposes unless specifically directed by a healthcare professional.

What special precautions should I follow?

Now, let’s discuss some special precautions you should follow when using Methyclothiazide:

  • Allergies and Sensitivities: Inform your healthcare provider if you are allergic to any sulfa drugs or have experienced allergic reactions to medications in the past. Methyclothiazide is a thiazide diuretic, and it is related to sulfa drugs.
  • Medical History: Share your complete medical history with your healthcare provider, including any underlying health conditions or past medical issues. This information can help your doctor determine whether Methyclothiazide is a suitable treatment for you.
  • Medication Interactions: Provide a list of all medications, supplements, and herbal products you are currently taking to your healthcare provider. Methyclothiazide may interact with other drugs, potentially affecting their effectiveness or causing adverse effects.
  • Electrolyte Monitoring: Methyclothiazide can affect the balance of electrolytes in your body, such as sodium and potassium. Your healthcare provider may recommend regular monitoring of your electrolyte levels, especially during the initial stages of treatment.
  • Blood Pressure Monitoring: Continue to monitor your blood pressure regularly, as directed by your healthcare provider. Methyclothiazide is often prescribed to control high blood pressure, and monitoring helps assess its effectiveness.
  • Dehydration and Fluid Intake: Be cautious about becoming dehydrated while taking Methyclothiazide. Ensure that you maintain an adequate fluid intake, as excessive fluid loss can lead to dehydration.
  • Orthostatic Hypotension: Methyclothiazide can cause a drop in blood pressure when standing up from a sitting or lying position, leading to dizziness or fainting. Be careful when changing positions, especially if you experience dizziness.
  • Follow Dosage Instructions: Take Methyclothiazide exactly as prescribed by your healthcare provider. Do not change the dosage or stop taking the medication without consulting your doctor.
  • Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the use of Methyclothiazide with your healthcare provider. The risks and benefits of using this medication during pregnancy and while breastfeeding should be carefully considered.
  • Regular Check-ups: Attend follow-up appointments with your healthcare provider to monitor your progress and adjust your treatment plan if necessary.

Always follow your healthcare provider’s instructions and guidance when using Methyclothiazide or any other medication, and do not hesitate to ask questions or seek clarification about any concerns you may have regarding your treatment.

What special dietary instructions should I follow?

Methyclothiazide is a thiazide diuretic used to treat high blood pressure and fluid retention. While taking Methyclothiazide, consider the following dietary instructions:

  • Sodium Intake: Thiazide diuretics like Methyclothiazide can increase the loss of sodium in the urine. To avoid electrolyte imbalances, it’s generally recommended to limit your sodium intake while using this medication. This includes reducing your consumption of high-sodium foods such as processed foods, canned soups, and salty snacks.
  • Potassium-Rich Foods: Methyclothiazide may cause a loss of potassium as well. To maintain appropriate potassium levels, consider incorporating potassium-rich foods into your diet, such as bananas, oranges, potatoes, spinach, and avocados. However, consult your healthcare provider for specific dietary recommendations based on your individual needs.
  • Fluid Intake: It’s important to stay well-hydrated while taking a diuretic like Methyclothiazide. Follow your healthcare provider’s advice regarding fluid intake to prevent dehydration.

What should I do if I forget a dose?

If you forget to take a dose of Methyclothiazide, follow these general guidelines:

  • Take it as soon as you remember: If you realize you missed a dose and it’s not too close to the time for your next scheduled dose, take it as soon as you remember.
  • Don’t double up: Do not take two doses to make up for the missed one. Taking an extra dose can increase the risk of side effects and complications.
  • Continue your regular schedule: Resume taking Methyclothiazide as prescribed by your doctor, and try to stick to your usual dosing schedule. If you’re unsure about what to do or have concerns, contact your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Methyclothiazide, like all medications, can cause side effects in some individuals. Not everyone will experience these side effects, and their severity can vary. Common side effects of Methyclothiazide may include:

  • Frequent Urination: Methyclothiazide is a diuretic, so it increases urine production. This can lead to more frequent urination.
  • Dehydration: Excessive urination can potentially lead to dehydration, which may cause symptoms such as dry mouth, increased thirst, weakness, dizziness, or dark-colored urine.
  • Low Blood Pressure: In some cases, Methyclothiazide can lower blood pressure too much, leading to symptoms like dizziness, lightheadedness, or fainting.
  • Electrolyte Imbalances: This medication can affect the balance of electrolytes in your body, including potassium, sodium, and calcium. Low potassium levels (hypokalemia) can cause muscle weakness, muscle cramps, and irregular heart rhythms.
  • High Blood Sugar: Methyclothiazide can increase blood sugar levels in some individuals, which may be a concern for people with diabetes.
  • Gout Flare-Ups: Some people may experience gout flare-ups due to increased uric acid levels caused by the diuretic effect of Methyclothiazide.
  • Elevated Blood Urea Nitrogen (BUN) and Serum Creatinine: This medication can affect kidney function, leading to higher BUN and serum creatinine levels in blood tests. These changes are usually reversible upon discontinuation of the medication.
  • Skin Reactions: Rarely, Methyclothiazide may cause skin reactions such as rash or photosensitivity (increased sensitivity to sunlight).
  • Digestive Issues: You may experience stomach upset, nausea, or vomiting when taking Methyclothiazide.
  • Elevated Blood Lipids: In some cases, this medication may lead to an increase in blood cholesterol and triglyceride levels.

It’s important to note that not everyone will experience these side effects, and many people tolerate Methyclothiazide well. Your healthcare provider will carefully consider the potential benefits and risks of the medication before prescribing it to you. They will also monitor your progress and conduct regular check-ups to assess your response to treatment and any potential side effects.

If you experience severe or persistent side effects, or if you have any concerns about the medication, contact your healthcare provider promptly. Do not stop taking Methyclothiazide or change your dosage without consulting your doctor, as this could affect your blood pressure control and overall health. Your healthcare provider can make adjustments to your treatment plan if necessary.

What should I know about storage and disposal of this medication?


  • Keep in its original container: Store Methyclothiazide in its original prescription container or packaging. This helps you identify the medication easily and provides information on dosage and instructions.
  • Room temperature: Store Methyclothiazide at room temperature, away from excessive heat, moisture, and direct sunlight. Avoid storing it in the bathroom, as the humidity can affect the medication’s stability.
  • Keep out of reach of children and pets: Store Methyclothiazide in a secure location where children and pets cannot access it. Accidental ingestion can be dangerous.


  • Follow disposal instructions: When you no longer need Methyclothiazide or when it reaches its expiration date, it’s important to dispose of it properly. Follow any disposal instructions provided by your pharmacist or healthcare provider.
  • Don’t flush down the toilet: Do not flush Methyclothiazide down the toilet unless specific disposal instructions indicate that it is safe to do so. Flushing medications can potentially harm the environment.
  • Take-back programs: Some pharmacies or local government agencies offer medication take-back programs, allowing you to safely dispose of unused or expired medications. Check if such programs are available in your area.

In case of emergency/overdose

In case of an emergency or suspected overdose of Methyclothiazide, take the following steps:

  • Seek immediate medical attention: Contact your local poison control center or go to the nearest emergency room. An overdose of Methyclothiazide can have serious consequences, including electrolyte imbalances and low blood pressure.
  • Be prepared: If possible, provide healthcare professionals with information about the medication, including its name, dosage, and when it was taken.

What other information should I know?

  • Regular follow-up: It’s crucial to attend all scheduled appointments with your healthcare provider while taking Methyclothiazide. They will monitor your blood pressure, electrolyte levels, and overall health to ensure the medication is working effectively and to address any potential side effects.
  • Other medications: Inform your healthcare provider of all medications, supplements, and herbal products you are taking, as they may interact with Methyclothiazide. Certain medications, such as other diuretics or medications that affect potassium levels, may require adjustments to your treatment plan.
  • Lifestyle modifications: Continue to follow any lifestyle modifications recommended by your healthcare provider, such as dietary changes, exercise, and stress management, to complement the effects of Methyclothiazide in managing your blood pressure or medical condition.
  • Pregnancy and breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the use of Methyclothiazide with your healthcare provider. They can help weigh the risks and benefits and may recommend alternative treatments.

Always follow your healthcare provider’s guidance and prescription instructions when taking Methyclothiazide, and do not hesitate to reach out to them with any questions or concerns. Your safety and well-being are paramount, and your healthcare provider is your best source of information and assistance regarding your medication.

Copyright © 2023