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Mescolor (Generic Chlorpheniramine)

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Why is this medication prescribed?

Chlorpheniramine is an antihistamine medication that is commonly prescribed to relieve symptoms associated with allergies and allergic reactions. It can be used to treat various allergic conditions, including:

  • Allergic Rhinitis: Chlorpheniramine can help alleviate symptoms such as sneezing, runny or itchy nose, and itchy or watery eyes caused by seasonal or perennial allergies.
  • Urticaria (Hives): It can be used to relieve itching and discomfort associated with hives, which are raised, itchy welts on the skin.
  • Allergic Conjunctivitis: Chlorpheniramine may be used to treat redness, itching, and swelling of the eyes caused by allergic conjunctivitis.
  • Allergic Dermatitis: This medication can be used to reduce itching and skin irritation due to allergic reactions.
  • Anaphylaxis: In some cases, chlorpheniramine may be used as part of the treatment for anaphylaxis, a severe and potentially life-threatening allergic reaction. However, it is usually combined with other medications such as epinephrine for this purpose.

How should this medicine be used?

Chlorpheniramine is available in various forms, including tablets, capsules, and liquid preparations. The dosing instructions may vary depending on the specific product and the age of the patient. It is essential to follow the prescribing doctor’s recommendations and the instructions on the medication label. Here are some general guidelines for using chlorpheniramine:

  • Dosage: Follow the recommended dosage prescribed by your healthcare provider or as directed on the product label. Dosage may vary depending on age, weight, and the specific condition being treated.
  • Frequency: Typically, chlorpheniramine is taken every 4 to 6 hours, but again, this may vary depending on the specific product. Do not exceed the recommended dose or frequency unless directed by your healthcare provider.
  • Administration: Take the medication with a full glass of water. You can take it with or without food, but it may work more quickly on an empty stomach.
  • Avoid Alcohol: It’s generally advisable to avoid alcohol while taking chlorpheniramine, as it can increase drowsiness and dizziness.
  • Duration: Use chlorpheniramine for the prescribed duration, even if your symptoms improve. If your symptoms persist or worsen, consult your healthcare provider.
  • Special Populations: Be cautious when giving chlorpheniramine to children, as dosages may be age-dependent. Always consult a pediatrician for appropriate dosing in children.
  • Side Effects: Common side effects may include drowsiness and dry mouth. Avoid activities that require mental alertness, such as driving or operating heavy machinery, until you know how the medication affects you.

As with any medication, it’s important to consult your healthcare provider or pharmacist for specific dosing instructions and potential interactions with other medications or medical conditions. Additionally, do not hesitate to seek medical attention if you experience severe side effects or suspect an overdose.

Other uses for this medicine

Chlorpheniramine may have other off-label uses, but it’s important to consult with a healthcare professional before using it for any condition not explicitly approved. Some potential off-label uses include:

  • Motion Sickness: Chlorpheniramine may be used to help relieve symptoms of motion sickness, such as nausea and dizziness.
  • Allergic Reactions: It can be used to manage mild allergic reactions, but more severe reactions often require a different class of medications like epinephrine.
  • Itching and Hives: Chlorpheniramine may be used to alleviate itching associated with skin conditions like hives.

What special precautions should I follow?

Special precautions and considerations when using chlorpheniramine:

  • Allergies: Inform your healthcare provider if you are allergic to chlorpheniramine or any other antihistamines.
  • Medical History: Share your complete medical history, including any pre-existing medical conditions, with your healthcare provider. They should know if you have a history of heart problems, high blood pressure, glaucoma, asthma, urinary retention, or prostate problems.
  • Pregnancy and Breastfeeding: If you are pregnant or breastfeeding, consult your healthcare provider before using chlorpheniramine. It’s important to weigh the potential benefits against the risks during pregnancy and breastfeeding.
  • Alcohol and Sedation: Avoid alcohol while taking chlorpheniramine, as it can increase drowsiness and impair your ability to perform tasks that require mental alertness, such as driving or operating machinery.
  • Interactions: Inform your healthcare provider about all the medications you are currently taking, including prescription, over-the-counter, herbal, or dietary supplements, as chlorpheniramine may interact with other drugs.
  • Children and the Elderly: Use caution when administering chlorpheniramine to children or the elderly, as they may be more sensitive to its effects. Follow age-appropriate dosing guidelines and consult a healthcare provider for guidance.
  • Side Effects: Be aware of common side effects, such as drowsiness, dry mouth, and dizziness. If these side effects are severe or persistent, consult your healthcare provider.
  • Overdose: Do not exceed the recommended dosage, as an overdose of chlorpheniramine can be dangerous. Seek medical attention immediately if you suspect an overdose or experience symptoms such as extreme drowsiness, hallucinations, rapid heart rate, or seizures.

Always use chlorpheniramine as directed by your healthcare provider or as indicated on the product label. If you have any questions or concerns about its use, consult your healthcare professional for guidance.

What special dietary instructions should I follow?

There are no specific dietary restrictions associated with chlorpheniramine. However, it’s essential to maintain a healthy and balanced diet to support your overall well-being, especially if you’re taking medications regularly. Eating a well-rounded diet can help your body absorb and metabolize medications effectively.

What should I do if I forget a dose?

If you forget to take a dose of chlorpheniramine:

  • Take it as soon as you remember: If it’s close to your next scheduled dose, skip the missed dose and resume your regular dosing schedule.
  • Do not double dose: Do not take a double dose to make up for the missed one. Taking more medication than prescribed can lead to side effects and may not improve your symptoms.
  • Set a Reminder: To avoid missing doses in the future, consider setting an alarm or using a medication reminder app to help you remember when to take your medication.

What side effects can this medication cause?

Chlorpheniramine, like all medications, can potentially cause side effects. Not everyone will experience these side effects, and their severity can vary from person to person. Common side effects of chlorpheniramine may include:

  • Drowsiness: One of the most common side effects of chlorpheniramine is drowsiness. This can impair your ability to concentrate or perform tasks that require mental alertness, such as driving or operating heavy machinery.
  • Dry Mouth: Chlorpheniramine can lead to a dry mouth or a feeling of thirst. Staying hydrated and using sugar-free gum or candy may help alleviate this symptom.
  • Dizziness: Some people may experience dizziness or lightheadedness when taking chlorpheniramine.
  • Blurred Vision: Chlorpheniramine can cause temporary blurred vision or difficulty focusing.
  • Constipation: In some individuals, chlorpheniramine may lead to constipation.
  • Urinary Retention: Rarely, chlorpheniramine can cause difficulty in passing urine or urinary retention.
  • Upset Stomach: Some people may experience stomach discomfort, nausea, or gastrointestinal disturbances.
  • Nervousness or Restlessness: In some cases, chlorpheniramine can cause nervousness or restlessness, especially in children.
  • Skin Reactions: Allergic skin reactions such as rash or hives are possible but relatively uncommon.
  • Heart Palpitations: Although rare, chlorpheniramine can, in some instances, cause irregular heartbeats or palpitations.

It’s important to note that the likelihood and severity of these side effects can vary depending on factors such as the dose, the specific chlorpheniramine product used, individual sensitivity, and interactions with other medications. If you experience severe or bothersome side effects, contact your healthcare provider.

In rare cases, some individuals may experience more serious side effects or allergic reactions to chlorpheniramine. Seek medical attention immediately if you experience any of the following:

  • Difficulty breathing or swallowing
  • Swelling of the face, lips, tongue, or throat
  • Severe dizziness or fainting
  • Rapid or irregular heartbeat
  • Hallucinations or confusion
  • Seizures

It’s crucial to use chlorpheniramine as directed by your healthcare provider and to inform them of any pre-existing medical conditions or other medications you may be taking to reduce the risk of potential side effects or drug interactions. If you have concerns about the side effects of chlorpheniramine or its suitability for your specific medical condition, consult your healthcare professional for guidance.

What should I know about storage and disposal of this medication?


  • Follow Instructions: Always store chlorpheniramine according to the specific instructions provided on the medication label or as directed by your healthcare provider or pharmacist.
  • Room Temperature: Typically, chlorpheniramine should be stored at room temperature, away from excessive heat, moisture, and direct sunlight. Avoid storing it in the bathroom, as moisture can degrade the medication.
  • Childproof Container: Keep chlorpheniramine in its original childproof container or packaging to prevent accidental ingestion by children or pets.
  • Out of Reach: Store the medication in a location that is out of reach and sight of children and pets.
  • Expiration Date: Check the expiration date on the medication label, and do not use chlorpheniramine if it has expired.

Handling and Disposal:

  • Proper Disposal: Dispose of chlorpheniramine safely and responsibly to prevent accidental ingestion by others. Do not flush medications down the toilet or pour them down the drain unless instructed to do so by your healthcare provider or a specific medication disposal program.
  • Take-Back Programs: Many communities have medication take-back programs or events that allow you to return unused or expired medications for safe disposal. Check with your local pharmacy or law enforcement agency for information on available disposal options in your area.
  • Medication Disposal Guidelines: If there are no take-back programs available, you can typically mix the medication with an unpalatable substance like dirt, cat litter, or used coffee grounds. Place this mixture in a sealed plastic bag or container before disposing of it in the trash. Remove or obliterate any personal information from the medication container before disposal.

In case of emergency/overdose

In the event of an overdose or if you suspect someone has taken too much chlorpheniramine, take the following steps:

  • Call 911: If the person is experiencing severe symptoms or is unresponsive, call emergency services immediately.
  • Poison Control Center: Contact your local poison control center or the national Poison Help hotline at 1-800-222-1222 (available 24/7) for guidance on how to proceed. Have information about the medication, including its name and strength, on hand.
  • Do Not Wait: Do not wait for symptoms to worsen; seek medical attention promptly.

What other information should I know

  • Follow Instructions: Always use chlorpheniramine as directed by your healthcare provider or as indicated on the medication label. Do not exceed the recommended dosage or frequency.
  • Interactions: Inform your healthcare provider and pharmacist about all the medications, supplements, and herbal products you are taking, as chlorpheniramine can interact with other drugs.
  • Allergies: Be sure to inform your healthcare provider of any known allergies or sensitivities to medications or substances.
  • Drowsiness: Be cautious when driving or operating heavy machinery, as chlorpheniramine can cause drowsiness or impairment.
  • Storage and Temperature: Avoid storing chlorpheniramine in extreme temperatures, as it may affect the stability and effectiveness of the medication.

Always consult your healthcare provider or pharmacist if you have specific questions or concerns about the use, storage, or disposal of chlorpheniramine or if you suspect an overdose. They can provide personalized guidance based on your situation and needs.

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