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Maxalt-MLT (Generic Rizatriptan)

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Why is this medication prescribed?

Maxalt-MLT is a brand name for the medication rizatriptan benzoate. It is primarily prescribed for the treatment of acute migraine headaches with or without aura in adults and adolescents (ages 6 to 17 years). Migraines are severe headaches often accompanied by other symptoms like nausea, vomiting, and sensitivity to light and sound. Maxalt-MLT belongs to a class of drugs called triptans, which work by narrowing the blood vessels in the brain to relieve the pain associated with migraines.

How should this medicine be used?

Here are some general guidelines on how Maxalt-MLT should be used, but it’s important to follow your healthcare provider’s specific instructions:

  • Dosage: Maxalt-MLT is available in orally disintegrating tablet form, which means it can be taken without water. The typical adult dose is 5 mg or 10 mg, taken as soon as you experience migraine symptoms. If the headache comes back or does not completely go away after the first dose, a second dose may be taken at least 2 hours after the first one, but you should not exceed a total dose of 30 mg in a 24-hour period.
  • Adolescents (ages 6 to 17): The dose for adolescents is based on their weight. Your healthcare provider will determine the appropriate dose for your child.
  • Administration: Place the Maxalt-MLT orally disintegrating tablet on your tongue and allow it to dissolve, usually within seconds. You do not need to chew or swallow it with water.
  • Timing: It is best to take Maxalt-MLT as soon as you feel a migraine coming on. It may be less effective if taken during the later stages of a migraine attack.
  • Monitoring: After taking Maxalt-MLT, pay attention to your migraine symptoms. If your headache does not improve or gets worse after the first dose, consult your healthcare provider before taking a second dose.
  • Precautions: Maxalt-MLT is not a preventative medication for migraines and should not be used for daily headache management. It should only be used to treat acute migraine attacks.
  • Avoid Overuse: Overuse of Maxalt-MLT or other migraine medications can lead to medication overuse headaches, also known as rebound headaches. To minimize this risk, use Maxalt-MLT as directed by your healthcare provider.
  • Side Effects: Like all medications, Maxalt-MLT can have side effects, including dizziness, tiredness, chest pain or tightness, and sensations of tingling, warmth, or pressure. If you experience any unusual or severe side effects, contact your healthcare provider.
  • Allergies and Interactions: Inform your healthcare provider of any allergies you may have or any other medications you are taking, as Maxalt-MLT can interact with certain drugs.

It’s essential to use Maxalt-MLT exactly as prescribed by your healthcare provider, and if you have any questions or concerns about its use, don’t hesitate to discuss them with your healthcare provider or pharmacist. They can provide you with personalized guidance based on your medical history and specific migraine symptoms.

Other uses for this medicine

Maxalt-MLT (rizatriptan benzoate) is primarily prescribed for the treatment of acute migraine headaches in adults and adolescents. It is not typically used for other medical conditions or purposes.

What special precautions should I follow?

Special precautions should be taken when using Maxalt-MLT, and it’s crucial to follow your healthcare provider’s instructions carefully. Here are some important precautions to keep in mind:

  • Medical History: Before starting Maxalt-MLT, inform your healthcare provider of your complete medical history, especially if you have a history of heart disease, high blood pressure, stroke, liver or kidney disease, or certain types of headaches.
  • Drug Interactions: Maxalt-MLT can interact with other medications, including certain antidepressants and other migraine medications. Inform your healthcare provider about all the medications and supplements you are taking to avoid potential interactions.
  • Allergies: If you are allergic to rizatriptan or any other ingredients in Maxalt-MLT, do not take the medication.
  • Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before using Maxalt-MLT.
  • Cardiovascular Risks: Maxalt-MLT can cause an increase in blood pressure, so it should be used with caution in individuals with a history of cardiovascular disease.
  • Serotonin Syndrome: Be cautious when using Maxalt-MLT in combination with other drugs that increase serotonin levels, as it can lead to a rare but serious condition called serotonin syndrome. Inform your healthcare provider of all the medications you are taking.

Always consult with your healthcare provider before starting or stopping any medication and follow their guidance closely. If you experience any unexpected or severe side effects while taking Maxalt-MLT, contact your healthcare provider promptly.

What special dietary instructions should I follow?

Maxalt-MLT is generally not associated with specific dietary restrictions. However, it’s essential to maintain a healthy diet and lifestyle to help manage migraines. Triggers for migraines can vary from person to person, but common dietary triggers include certain foods and beverages, such as caffeine, alcohol, aged cheeses, processed meats, and artificial sweeteners. Keeping a food diary may help identify and avoid specific triggers that worsen your migraines.

What should I do if I forget a dose?

If you miss a dose of Maxalt-MLT, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Maxalt-MLT (rizatriptan) is a medication commonly prescribed to treat migraines. Like all medications, it can have side effects. Here are some of the common side effects associated with Maxalt-MLT:

Common side effects:

  • Pain or tight feeling in the chest or throat: This sensation can occur shortly after taking Maxalt-MLT. It’s usually temporary but should be reported to your healthcare provider.
  • Warmth, tingling, or redness under the skin: Some people may experience these sensations, which are usually mild and transient.
  • Dizziness: Maxalt-MLT can cause dizziness in some individuals.
  • Drowsiness: You may feel drowsy or tired after taking this medication.
  • Nausea and vomiting: Some people may experience nausea or even vomiting as a side effect.
  • Dry mouth: This is another possible side effect.
  • Muscle pain or stiffness: Some individuals may experience muscle-related side effects.
  • Jaw or neck pain: This is a less common side effect but can occur.
  • Chest discomfort: This can include sensations such as pressure, heaviness, or pain in the chest. If you experience this, it’s essential to seek medical attention promptly.
  • Shortness of breath: This is a less common side effect but should be reported to a healthcare provider if experienced.

It’s important to note that not everyone will experience these side effects, and many people tolerate Maxalt-MLT well. If you experience any severe or concerning side effects, contact your healthcare provider immediately.

What should I know about storage and disposal of this medication?

Storage and disposal of Maxalt-MLT:


  • Store Maxalt-MLT at room temperature, away from excessive heat and moisture.
  • Keep the medication in its original packaging or container to protect it from light and moisture.
  • Do not refrigerate Maxalt-MLT unless directed to do so by your healthcare provider or pharmacist.


  • Dispose of Maxalt-MLT tablets that are no longer needed or have expired in a safe and responsible manner.
  • Do not flush Maxalt-MLT down the toilet or pour it down the drain unless instructed to do so by local regulations. Medication disposal guidelines may vary by location.
  • Check with your local pharmacy or healthcare provider for information on proper medication disposal in your area. Some pharmacies offer medication take-back programs or disposal services.

In case of emergency/overdose

In case of an overdose or emergency related to Maxalt-MLT, seek immediate medical attention or contact a poison control center. An overdose of Maxalt-MLT may lead to symptoms such as:

  • Severe chest pain.
  • Irregular heartbeats.
  • Shortness of breath.
  • Fainting.

It’s important to use Maxalt-MLT only as prescribed by your healthcare provider and not to exceed the recommended dosage. If you suspect an overdose or experience severe or unusual symptoms after taking Maxalt-MLT, do not hesitate to seek medical help.

What other information should I know?

  • Patient Education: Make sure you understand how to use Maxalt-MLT properly. If you have any questions or concerns about its use, dosing, or potential side effects, discuss them with your healthcare provider or pharmacist.
  • Monitoring: Pay attention to how Maxalt-MLT affects you, especially regarding any dizziness or drowsiness. Avoid activities that require mental alertness, such as driving, until you know how the medication affects you.
  • Migraine Diary: Keeping a migraine diary can help you and your healthcare provider track the frequency, duration, and severity of your migraines. This information can be valuable in assessing the effectiveness of Maxalt-MLT and making treatment adjustments if necessary.
  • Follow-up: Follow up with your healthcare provider as scheduled to discuss your migraine treatment plan. If your migraines do not improve or worsen, let your healthcare provider know so that adjustments can be made.
  • Medication List: Keep a list of all medications you are currently taking, including Maxalt-MLT, and provide this list to any healthcare provider you see. This can help prevent potential drug interactions or complications.
  • Emergency Medical ID: Some people with severe migraines may benefit from having an emergency medical identification (ID) bracelet or card that includes information about their condition and the medication they are taking, especially if they are at risk of becoming unconscious during a migraine attack.

Always follow the guidance and recommendations of your healthcare provider regarding the use of Maxalt-MLT and consult them if you have any questions or concerns about your treatment.

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