Lenvima (Generic Lenvatinib)
Actual product appearance may differ slightly.
Click the CARD below to print or take a screenshot on your mobile phone or tablet. There is no need to download another app!
If you would like to personalize your card enter your full name in the member name field below the card at this link and click the Update button.
Why is this medication prescribed?
Lenvatinib is used to treat a certain type of thyroid cancer that has spread to other parts of the body and cannot be treated with radioactive iodine. Lenvatinib is in a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps stop the spread of cancer cells.
How should this medicine be used?
Lenvatinib comes as a capsule to take by mouth. It is usually taken once daily with or without food. Take lenvatinib at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take lenvatinib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Your doctor may decrease your dose of lenvatinib or tell you to stop taking the medication for a time or permanently if you experience serious side effects. Be sure to talk to your doctor about how you are feeling during your treatment with lenvatinib.
The length of your treatment depends on how well you respond to the medication and the side effects you experience. Continue to take lenvatinib even if you feel well. Do not stop taking lenvatinib without talking to your doctor.
Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking lenvatinib,
- Tell your doctor and pharmacist if you are allergic to lenvatinib, any other medications, or any of the ingredients in lenvatinib capsules. Ask your pharmacist for a list of the ingredients.
- Tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: certain medications for irregular heartbeat including amiodarone (Cordarone, Nexterone, Pacerone), disopyramide (Norpace), procainamide, quinidine (in Nuedexta), and sotalol (Betapace, Betapace AF, Sorine, Sotylize). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- Tell your doctor if you have or have ever had seizures, high blood pressure, a stroke, a heart attack, headaches, changes in vision, especially those due to blood clots, a fistula (abnormal connection between 2 organs inside your body or between an organ and the outside of your body), a tear in the wall of your stomach or intestine, QT interval prolongation (an irregular heart rhythm that can lead to fainting, loss of consciousness, seizures, or sudden death), low levels of calcium, potassium, or magnesium in your blood, bleeding problems, or heart, kidney, or liver disease.
- You should know that lenvatinib may decrease fertility in men and women. However, you should not assume that you or your partner cannot become pregnant. Tell your doctor if you are pregnant or plan to become pregnant. If you can become pregnant, you should use birth control during your treatment with lenvatinib and for at least 2 weeks after your treatment. If you become pregnant while you are taking lenvatinib, call your doctor immediately. Lenvatinib may harm the fetus.
- Tell your doctor if you are breastfeeding or plan to breastfeed. You should not breastfeed while taking lenvatinib.
- You should know that your blood pressure may increase during your treatment with lenvatinib. Your doctor will probably monitor your blood pressure during your treatment.
What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
What should I do if I forget a dose?
If your next dose is due in 12 hours or more, take the missed dose as soon as you remember it. However, if the next dose will be taken in less than 12 hours, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
Lenvatinib may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- Fatigue or tiredness
- Rash, redness, itching, or peeling of skin on palms and sole(s) of the feet
- Decreased appetite
- Weight loss
- Change in ability to taste food
- Mouth sores
- Dry mouth
- Joint and muscle pain
- Difficulty falling asleep or staying asleep
- Hair loss
- Burning during urination
Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:
- Shortness of breath
- Swelling of legs and ankles
- Chest pain
- Numbness or weakness of the face, arm, or leg on one side of your body
- Pain in arms, back, neck, or jaw
- Sudden, severe headache
- Slow or difficult speech
- Sudden changes in vision
- Yellowing of the skin or eyes
- Stomach pain
- Dark (tea-colored) urine
- Light-colored stools
- Severe and persistent nose bleeds
- Bloody vomit
- Black, tarry, or bloody stools
- Coughing up blood or blood clots
- Heavy menstrual bleeding
- Vomiting, diarrhea, or signs of dehydration
Lenvatinib may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
What should I know about storage and disposal of this medication?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA’s Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org
In case of emergency/overdose
In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can’t be awakened, immediately call emergency services at 911.
What other information should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body’s response to lenvatinib.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.