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Kerendia (Generic Finerenone)

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Why is this medication prescribed?

Finerenone is a prescription medication that belongs to a class of drugs called mineralocorticoid receptor antagonists. It is primarily prescribed for the treatment of a specific type of chronic kidney disease (CKD) called diabetic kidney disease (DKD) in patients with type 2 diabetes.

Diabetic kidney disease is a progressive condition characterized by damage to the kidneys due to long-standing diabetes. It is one of the leading causes of end-stage renal disease (ESRD) and requires effective management to slow down its progression. Finerenone has been specifically developed to address this condition and its associated complications.

Finerenone works by blocking the effects of a hormone called aldosterone, which plays a role in fluid balance and blood pressure regulation. By inhibiting aldosterone, finerenone reduces the amount of protein excreted in the urine, thereby helping to preserve kidney function and slow the progression of diabetic kidney disease. It may also have beneficial effects on blood pressure and cardiovascular outcomes.

How should this medicine be used?

Finerenone should be used exactly as prescribed by a healthcare professional. It is typically available in tablet form and is taken orally with or without food.

The recommended dosage and treatment duration may vary depending on the individual’s condition and response to the medication. It is important to follow the prescribed dose and schedule provided by the healthcare professional.

It is generally advised not to exceed the recommended dose or alter the dosage without consulting a healthcare provider. If a dose is missed, it should be taken as soon as remembered unless it is close to the next scheduled dose. In such cases, the missed dose should be skipped, and the regular dosing schedule should be resumed.

It is important to continue taking finerenone even if symptoms improve, unless directed otherwise by a healthcare professional. Abruptly stopping the medication can have adverse effects and may worsen the condition.

If any questions or concerns arise about the usage of finerenone, it is best to consult a healthcare professional who can provide personalized guidance and recommendations based on the individual’s specific situation.

Other uses for this medicine

While the primary use of finerenone is for the treatment of diabetic kidney disease (DKD), there are no other officially approved uses for this medication. However, it’s important to note that medical research and clinical trials are constantly ongoing, and new uses for medications may emerge over time. It’s always best to consult with a healthcare professional for the most up-to-date and accurate information on the uses of finerenone.

What special precautions should I follow?

Regarding special precautions, it’s essential to consider the following:

  • Allergies: Inform your healthcare provider if you have any known allergies or hypersensitivity to finerenone or any of its components. This information is crucial to prevent any adverse reactions.
  • Medication Interactions: Certain medications may interact with finerenone and affect its efficacy or increase the risk of side effects. It is important to inform your healthcare provider about all the medications, supplements, and herbal products you are taking before starting finerenone.
  • Pregnancy and Breastfeeding: Finerenone is generally not recommended for use during pregnancy as it may harm the unborn baby. It is important to discuss the potential risks and benefits with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.
  • Pre-existing Conditions: Inform your healthcare provider about any pre-existing medical conditions you have, such as liver disease, kidney disease, electrolyte imbalances, or heart conditions. Finerenone may require dosage adjustments or special monitoring in these situations.
  • Side Effects: Like any medication, finerenone can cause side effects. Common side effects may include dizziness, diarrhea, high potassium levels (hyperkalemia), and urinary tract infections. If you experience any unusual or severe side effects, it is important to notify your healthcare provider promptly.
  • Regular Monitoring: Your healthcare provider may order regular blood tests to monitor kidney function, potassium levels, and other relevant parameters while taking finerenone. This is to ensure the medication is working effectively and to monitor for any potential complications.

It’s crucial to consult with a healthcare professional or read the medication’s prescribing information for comprehensive and specific precautions associated with finerenone, as they can provide personalized advice based on your medical history and condition.

What special dietary instructions should I follow?

When taking finerenone, there are no specific dietary instructions that need to be followed. However, it’s generally recommended to maintain a balanced and healthy diet as advised by your healthcare provider. It is important to follow any dietary recommendations or restrictions provided by your healthcare professional, especially if you have conditions such as high blood pressure or kidney disease.

What should I do if I forget a dose?

If you forget to take a dose of finerenone, it is generally recommended to take it as soon as you remember. However, if it is close to the time for your next scheduled dose, it is advisable to skip the missed dose and continue with your regular dosing schedule. Taking a double dose to make up for the missed one is not recommended.

What side effects can this medication cause?

Finerenone, like any medication, may cause side effects. It’s important to note that not everyone who takes finerenone will experience these side effects, and the severity and frequency can vary from person to person. Some potential side effects of finerenone may include:

  • Hyperkalemia: Finerenone may cause high levels of potassium in the blood, a condition known as hyperkalemia. Symptoms of hyperkalemia may include weakness, fatigue, palpitations, or irregular heartbeat. Regular monitoring of potassium levels is typically recommended while taking finerenone.
  • Urinary Tract Infections: Some individuals may experience urinary tract infections (UTIs) while taking finerenone. Symptoms of UTIs can include frequent urination, burning sensation during urination, cloudy or bloody urine, or lower abdominal pain.
  • Diarrhea: Diarrhea is a potential side effect of finerenone. If persistent or severe diarrhea occurs, it is important to inform your healthcare provider.
  • Dizziness: Some individuals may experience dizziness or lightheadedness while taking finerenone. It is recommended to avoid activities that require alertness until you know how the medication affects you.
  • Low blood pressure: Finerenone may cause a decrease in blood pressure, leading to symptoms such as dizziness or lightheadedness. Blood pressure should be monitored regularly during treatment.
  • Other potential side effects: Other less common side effects may include headache, nausea, cough, muscle cramps, or changes in kidney function. It’s important to report any unusual or severe side effects to your healthcare provider.

This is not an exhaustive list of all possible side effects. If you experience any side effects while taking finerenone or have concerns, it is crucial to contact your healthcare provider promptly. They can provide guidance, evaluate the symptoms, and determine the appropriate course of action.

Additionally, it’s important to read the medication’s prescribing information or consult a healthcare professional for a comprehensive list of potential side effects associated with finerenone, as they can provide personalized advice based on your medical history and condition.

What should I know about storage and disposal of this medication?

  • Storage: Finerenone should be stored at room temperature, away from moisture and heat. It is generally recommended to keep the medication in its original container with the lid tightly closed. Always follow any specific storage instructions provided by your healthcare provider or the medication’s packaging.
  • Disposal: Proper disposal of medications is important to prevent accidental ingestion or environmental contamination. It is recommended to follow local guidelines or consult a pharmacist for specific instructions on how to safely dispose of finerenone. Do not flush the medication down the toilet unless instructed to do so.

In case of emergency/overdose

In case of an emergency or suspected overdose, it is crucial to seek immediate medical attention by calling your local emergency services or contacting a poison control center. Be sure to inform the medical professionals about the medication you have taken and the dosage.

What other information should I know?

  • Keep all medications, including finerenone, out of the reach of children and pets.
  • Inform all healthcare providers involved in your care, such as doctors, dentists, or surgeons, that you are taking finerenone. This helps them make informed decisions regarding other medications or procedures.
  • Attend regular follow-up appointments with your healthcare provider to monitor your condition, response to treatment, and any potential side effects.
  • Do not share finerenone with others, even if they have similar symptoms or conditions. The medication should only be used under the supervision and prescription of a healthcare professional.
  • If you are scheduled for any laboratory tests, inform the healthcare provider conducting the tests that you are taking finerenone, as it may affect certain test results.

Remember, the information provided here is a general guideline. For specific instructions on storage, disposal, emergency procedures, or any other concerns related to finerenone, it is best to consult with your healthcare provider or refer to the medication’s prescribing information.

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