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Januvia (Generic Sitagliptin)

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Why is this medication prescribed?

Januvia is a brand name for the medication sitagliptin, which is prescribed for the treatment of type 2 diabetes mellitus. It belongs to a class of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors.

Januvia is typically prescribed to help control blood sugar levels in people with type 2 diabetes. It works by increasing the levels of incretin hormones in the body, which stimulate the release of insulin and reduce the production of glucose by the liver. By doing so, Januvia helps lower blood sugar levels.

How should this medicine be used?

Here are some important points to consider regarding the use of Januvia:

  • Dosage: The recommended dose of Januvia is usually 100 mg taken orally once daily. However, the dosage may vary depending on individual factors, such as kidney function and other medications being taken. It is important to follow the prescribed dosage as instructed by your healthcare provider.
  • Timing: Januvia can be taken with or without food. It is generally recommended to take it around the same time each day to maintain a consistent level of the medication in the body.
  • Combination therapy: Januvia can be used alone or in combination with other antidiabetic medications, such as metformin or insulin. Your healthcare provider will determine the appropriate treatment plan for your specific needs.
  • Kidney function: If you have impaired kidney function, the dosage of Januvia may need to be adjusted. It is important to inform your healthcare provider about any existing kidney problems.
  • Compliance: It is essential to take Januvia as prescribed by your healthcare provider. Do not adjust the dosage or stop taking it without consulting your doctor.
  • Side effects: Januvia is generally well-tolerated, but like any medication, it can have side effects. Common side effects may include upper respiratory tract infections, headaches, and stomach upset. If you experience any severe or persistent side effects, contact your healthcare provider.

Remember, this information is a general overview, and it is important to consult with a healthcare professional for personalized advice regarding the use of Januvia or any other medication.

Other uses for this medicine

Januvia (generic name: sitagliptin) is primarily used to treat type 2 diabetes mellitus. It belongs to a class of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors, which help regulate blood sugar levels by increasing the levels of certain hormones that stimulate insulin production.

Apart from its main use in managing diabetes, there are no other approved medical uses for Januvia. It is important to note that medications should only be used for their approved indications unless specifically prescribed by a healthcare professional for off-label use.

What special precautions should I follow?

Regarding precautions, it is essential to follow your healthcare provider’s instructions and the medication’s prescribed guidelines. Here are some general precautions to consider while taking Januvia:

  • Allergies: Inform your doctor if you have any known allergies to sitagliptin or any other ingredients in Januvia.
  • Medical history: Provide your healthcare provider with a comprehensive medical history, especially if you have a history of pancreatitis, kidney disease, or any other serious health conditions.
  • Pregnancy and breastfeeding: Januvia’s safety during pregnancy and breastfeeding has not been established. Consult with your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
  • Drug interactions: Inform your healthcare provider about all the medications, supplements, and herbal products you are taking, as Januvia may interact with certain drugs. This includes both prescription and over-the-counter medications.
  • Hypoglycemia: Januvia is generally not associated with causing low blood sugar (hypoglycemia) on its own. However, when combined with other diabetes medications that can cause hypoglycemia, it may increase the risk. Inform your doctor if you experience symptoms of low blood sugar, such as sweating, dizziness, shakiness, or confusion.
  • Pancreatitis: In rare cases, pancreatitis (inflammation of the pancreas) has been reported with Januvia use. Contact your doctor immediately if you experience persistent severe abdominal pain that may radiate to your back, with or without vomiting.

Always follow the instructions provided by your healthcare provider and read the medication’s accompanying leaflet for specific precautions and potential side effects associated with Januvia. It is crucial to have regular check-ups and blood sugar monitoring while taking this medication.

What special dietary instructions should I follow?

Januvia does not have specific dietary restrictions. However, it is crucial to maintain a healthy diet and follow any dietary recommendations provided by your healthcare provider or dietitian. Focus on consuming a balanced diet that includes whole grains, lean proteins, fruits, vegetables, and limited amounts of processed foods, sugary beverages, and saturated fats. Pay attention to carbohydrate intake and distribute it evenly throughout your meals. Monitoring your carbohydrate intake can help you manage your blood sugar levels effectively. Avoid excessive alcohol consumption as it can increase the risk of hypoglycemia (low blood sugar) and impair the effectiveness of Januvia.

What should I do if I forget a dose?

If you forget to take a dose of Januvia, here are some general guidelines:

  • Take the missed dose as soon as you remember, unless it is close to the time for your next scheduled dose. In that case, skip the missed dose and resume your regular dosing schedule.
  • Do not take a double dose to make up for the missed dose. Taking more than the prescribed amount can increase the risk of side effects.
  • If you are unsure about what to do, contact your healthcare provider or pharmacist for advice. They can provide specific instructions based on your individual circumstances.

What side effects can this medication cause?

Januvia (sitagliptin) can cause side effects, although not everyone experiences them. It’s important to note that side effects can vary in severity and individual response. Common side effects of Januvia include:

  • Upper respiratory tract infection: Symptoms may include a stuffy or runny nose, sore throat, cough, or fever.
  • Headache: Mild to moderate headaches can occur.
  • Stomach upset: This may include symptoms such as nausea, diarrhea, or stomach pain.
  • Diarrhea: Some individuals may experience loose stools or increased bowel movements.
  • Nausea: A feeling of discomfort or queasiness in the stomach.
  • Pancreatitis: Although rare, Januvia has been associated with pancreatitis, which is inflammation of the pancreas. Seek medical attention immediately if you experience severe abdominal pain, persistent nausea or vomiting, or unexplained weight loss.

It’s important to contact your healthcare provider if you experience any side effects, especially if they are severe, persistent, or concerning. They can evaluate your symptoms and determine the best course of action. It’s worth noting that this list does not include all possible side effects. Some people may experience uncommon or rare side effects that are not mentioned here. Always refer to the medication’s package insert or consult your healthcare provider for a comprehensive list of potential side effects associated with Januvia.

What should I know about storage and disposal of this medication?


  • Store Januvia at room temperature, preferably between 68°F and 77°F (20°C and 25°C).
  • Keep the medication in its original container or packaging to protect it from moisture and light.
  • Avoid storing Januvia in areas with excessive heat or cold, such as in direct sunlight, near a stove, or in the refrigerator.
  • Keep Januvia out of the reach of children and pets.


  • Do not dispose of Januvia by flushing it down the toilet or pouring it down the drain unless specifically instructed to do so by your healthcare provider or the medication’s instructions.
  • Ask your pharmacist or healthcare provider about approved methods of medication disposal in your area, such as using a drug take-back program or a medication disposal bag.
  • If no specific disposal instructions are available, you can mix Januvia with an undesirable substance like used coffee grounds or cat litter in a sealed plastic bag before throwing it in the trash. This helps prevent accidental ingestion by animals or people.

In case of emergency/overdose

In case of an emergency or suspected overdose, take the following steps:

  • Immediately call your local emergency number (such as 911 in the United States) or seek medical attention.
  • Inform the healthcare provider about the medication taken, including the name (Januvia), strength, and the amount ingested, if known.
  • If possible, take the Januvia packaging or bottle with you to the emergency room or doctor’s office.
  • Do not induce vomiting unless directed by medical professionals.

What other information should I know?

  • Januvia is a medication prescribed specifically for you. Do not share it with others even if they have similar symptoms.
  • Inform your healthcare provider about all medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements, as they may interact with Januvia.
  • Follow your doctor’s instructions regarding the dosage and timing of Januvia. Do not change the dose or stop taking it without consulting your healthcare provider.
  • Be aware of any signs of low blood sugar (hypoglycemia) or high blood sugar (hyperglycemia) and contact your doctor if you experience any unusual symptoms.
  • Attend regular follow-up appointments with your healthcare provider to monitor your diabetes management and the effectiveness of Januvia.

Remember, it’s crucial to consult your healthcare provider or pharmacist for specific instructions and information tailored to your situation.

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