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Invokana (Generic Canagliflozin)

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Why is this medication prescribed?

Invokana is primarily prescribed to help manage blood sugar levels in adults with type 2 diabetes. Type 2 diabetes is a chronic condition characterized by the body’s inability to properly use insulin or produce enough insulin, resulting in elevated blood sugar levels.

Invokana belongs to a class of medications called sodium-glucose cotransporter-2 (SGLT2) inhibitors. This drugs work by inhibiting the SGLT2 protein in the kidneys, which reduces the reabsorption of glucose and allows excess glucose to be excreted in the urine. By increasing the excretion of glucose, Invokana helps lower blood sugar levels in individuals with type 2 diabetes.

In addition to its blood sugar-lowering effects, Invokana may also have other benefits, such as promoting weight loss and reducing the risk of cardiovascular events in certain individuals with type 2 diabetes.

How should this medicine be used?

Invokana should be used exactly as prescribed by a healthcare professional. It is important to follow the recommended dosage and administration instructions. Here are some general guidelines for using Invokana:

  • Dosage: The specific dosage of Invokana will be determined by the healthcare professional based on individual factors such as the severity of diabetes, renal function, and other medications being taken. The typical starting dose is 100 mg once daily, but it may be adjusted to 300 mg once daily if necessary.
  • Timing: Invokana is usually taken orally once a day, with or without food. It is important to take it at the same time each day to maintain a consistent level of the medication in the body.
  • Swallowing: Invokana tablets should be swallowed whole with a glass of water. Do not crush, chew, or break the tablets before swallowing.
  • Additional instructions: It is crucial to follow any additional instructions provided by the healthcare professional, including dietary recommendations, regular exercise, and monitoring blood sugar levels. Regular follow-up appointments with the healthcare professional are also essential for monitoring progress and adjusting the treatment plan if necessary.

It’s important to note that these guidelines are general and may vary depending on individual circumstances. It is always best to consult a healthcare professional for personalized instructions and to address any specific concerns or questions regarding the use of Invokana.

Other uses for this medicine

Invokana (generic name canagliflozin) is a medication primarily used to treat type 2 diabetes. For accurate and personalized information about medication uses and precautions, it’s always best to consult a healthcare provider or pharmacist.

What special precautions should I follow?

Regarding precautions, it’s crucial to consult with a healthcare professional or read the medication’s prescribing information for specific details. However, here are some general precautions associated with Invokana:

  • Hypersensitivity: If you are allergic to canagliflozin or any of the ingredients in Invokana, you should avoid using the medication.
  • Renal Impairment: Invokana is not recommended for individuals with severe kidney problems or those on dialysis. It’s important to inform your healthcare provider about any pre-existing kidney conditions.
  • Diabetic Ketoacidosis (DKA): Invokana may increase the risk of developing DKA, a serious complication characterized by high levels of ketones in the blood. Symptoms of DKA include excessive thirst, frequent urination, nausea, vomiting, abdominal pain, fatigue, and confusion. If these symptoms occur, medical attention should be sought immediately.
  • Genital Infections: Invokana may increase the risk of genital fungal infections in both males and females. It is important to maintain proper hygiene and seek medical advice if any symptoms, such as itching, burning, or unusual discharge, occur in the genital area.
  • Hypotension (Low Blood Pressure): Invokana may cause a slight decrease in blood pressure. This effect may be more pronounced in individuals with pre-existing low blood pressure. Monitoring blood pressure regularly is advisable.
  • Ketoacidosis in Type 1 Diabetes: Invokana is not approved for the treatment of type 1 diabetes, and its use in this population may increase the risk of diabetic ketoacidosis.

These are just a few examples of precautions associated with Invokana, and there may be other important considerations depending on an individual’s medical history, current medications, and other factors. Always consult with a healthcare professional for accurate and personalized information regarding medications.

What special dietary instructions should I follow?

Special dietary instructions for Invokana:

  • Hydration: It is important to maintain adequate hydration while taking Invokana. Ensure that you drink enough fluids to prevent dehydration. However, consult your healthcare provider for specific recommendations based on your individual needs.
  • Carbohydrate intake: Invokana works by increasing the amount of glucose excreted through urine. While there are no specific dietary restrictions, it is generally recommended to follow a balanced and healthy diet that is suitable for managing diabetes. This may involve monitoring your carbohydrate intake, consuming a variety of nutrient-rich foods, and working with a registered dietitian or healthcare professional to develop a meal plan that meets your individual needs.
  • Alcohol consumption: It is advisable to limit alcohol consumption while taking Invokana, as alcohol can affect blood sugar levels and increase the risk of hypoglycemia (low blood sugar). Discuss alcohol consumption guidelines with your healthcare provider.

What should I do if I forget a dose?

If you accidentally forget to take a dose of Invokana, here are some general steps to follow:

  • Take the missed dose as soon as you remember, unless it is close to the time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule.
  • Do not take a double dose to make up for the missed one. Taking more than the prescribed dose can increase the risk of side effects.
  • If you have any concerns or questions about missed doses, it is best to consult your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Invokana (generic name canagliflozin) is a medication used to treat type 2 diabetes by helping lower blood sugar levels. Like any medication, Invokana can potentially cause side effects in some individuals. Common side effects of Invokana may include:

  • Genital yeast infections or urinary tract infections: Invokana works by increasing the amount of sugar excreted in the urine, which can create an environment conducive to infections in the genital area or urinary tract.
  • Increased urination: Invokana can cause an increase in urination frequency as it helps the body eliminate excess glucose through urine.
  • Thirst and dry mouth: The increased urination caused by Invokana may lead to dehydration, resulting in increased thirst and dry mouth.
  • Dizziness or lightheadedness: Some people may experience dizziness or lightheadedness, particularly when standing up quickly, due to the medication’s effects on blood pressure.
  • Low blood pressure: Invokana can cause a decrease in blood pressure, leading to symptoms such as lightheadedness, dizziness, or fainting.
  • Hypoglycemia (low blood sugar): While Invokana primarily works to lower blood sugar levels, it can occasionally lead to hypoglycemia, especially when used in combination with other diabetes medications that also lower blood sugar.
  • Increased cholesterol levels: Invokana may cause an increase in LDL cholesterol (the “bad” cholesterol) and a decrease in HDL cholesterol (the “good” cholesterol) in some individuals.
  • Increased risk of urinary tract infections: Some studies have indicated a higher risk of urinary tract infections with Invokana use.
  • Increased risk of bone fractures: Certain studies have suggested a potential increased risk of bone fractures, particularly in postmenopausal women.
  • Ketoacidosis: Although rare, Invokana can increase the risk of a serious condition called diabetic ketoacidosis, which is characterized by high levels of ketones in the blood.

It’s important to note that these are not exhaustive lists of side effects, and the effects experienced by individuals can vary. If you are taking Invokana and experience any concerning symptoms or side effects, it is essential to consult your healthcare provider for proper evaluation and guidance.

What should I know about storage and disposal of this medication?


  • Keep Invokana in its original container with the lid tightly closed.
  • Store at room temperature, away from moisture and heat.
  • Do not store Invokana in the bathroom or kitchen, as the humidity and temperature changes in these areas can affect its stability.
  • Keep Invokana out of reach of children and pets.


  • Follow your local regulations or guidelines for the proper disposal of medication.
  • Do not dispose of Invokana by flushing it down the toilet or pouring it down the drain unless specifically instructed to do so by your healthcare provider or pharmacist.
  • If you are unsure about the proper disposal method, consult your pharmacist or local waste management authorities for guidance.

In case of emergency/overdose

In case of an emergency or overdose involving Invokana, take the following steps:

  • Call your local emergency services (e.g., 911) immediately.
  • Inform the emergency personnel about the medication involved and the amount taken.
  • If possible, have the original container or packaging of Invokana available for reference.
  • Do not induce vomiting unless instructed to do so by medical professionals.

What other information should I know?

  • Invokana may increase the risk of a rare but serious condition called ketoacidosis, which can lead to diabetic coma or death. Seek medical attention if you experience symptoms such as nausea, vomiting, stomach pain, confusion, unusual fatigue, or difficulty breathing.
  • Inform your healthcare provider about all your medical conditions, including kidney problems, liver problems, and any allergies, before starting Invokana.
  • Invokana may cause dehydration and low blood pressure, especially in elderly patients. Stay adequately hydrated and consult your doctor if you experience symptoms such as dizziness, lightheadedness, or fainting.
  • Invokana may increase the risk of urinary tract infections and yeast infections. Contact your healthcare provider if you develop symptoms such as burning or pain during urination, frequent urination, or vaginal itching or discharge.
  • It is important to monitor your blood sugar levels regularly and follow your healthcare provider’s instructions regarding diet, exercise, and other diabetes management strategies while taking Invokana.

Remember, it is crucial to consult your healthcare provider or pharmacist for personalized guidance and specific instructions regarding the storage, disposal, and management of Invokana based on your individual circumstances.

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