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Intrarosa (Generic Prasterone Vaginal)

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Why is this medication prescribed?

Intrarosa is a prescription medication used to treat a common symptom of menopause called dyspareunia, which refers to pain during sexual intercourse. It is specifically indicated for postmenopausal women.

Intrarosa contains the active ingredient prasterone, which is a form of dehydroepiandrosterone (DHEA). DHEA is a hormone naturally produced by the body, and it plays a role in the maintenance of vaginal tissues.

When women go through menopause, the levels of estrogen in their bodies decrease, leading to thinning, drying, and inflammation of the vaginal tissues. This can result in pain during sexual intercourse. Intrarosa helps to alleviate this symptom by supplementing the DHEA levels in the vagina, which may improve vaginal tissues and reduce pain.

How should this medicine be used?

Intrarosa is a prescription medication used to treat dyspareunia (painful intercourse) in postmenopausal women. Here are the general instructions for using Intrarosa:

  • Wash your hands thoroughly before handling the medication.
  • Remove one vaginal insert from its foil pouch.
  • Choose a comfortable position, such as lying down, squatting, or standing with one leg elevated (you can use a bed or chair for support).
  • Hold the applicator by the barrel and gently shake it to ensure the insert is securely in place.
  • With your free hand, spread the labia apart to expose the vaginal opening.
  • Gently insert the applicator into the vagina as deeply as it is comfortable for you. It may be helpful to relax your muscles and breathe slowly.
  • Press the plunger firmly to release the insert into the vagina.
  • Once the insert is released, withdraw the applicator from the vagina.
  • Discard the used applicator in a waste bin.

Intrarosa is typically used once daily, preferably at bedtime. However, follow the specific instructions provided by your healthcare provider or the package insert. If you have any concerns or questions about the usage of Intrarosa, it is best to consult with your healthcare provider or pharmacist for personalized guidance. They can provide you with detailed instructions based on your specific condition and needs.

Other uses for this medicine

Intrarosa is primarily prescribed for the treatment of dyspareunia (painful intercourse) in postmenopausal women. It is specifically indicated for this use. However, it’s worth noting that medications may sometimes be prescribed “off-label,” meaning they may be used for purposes other than those officially approved by regulatory authorities. If your healthcare provider determines that there may be potential benefits for using Intrarosa for a different condition or symptom, they may prescribe it off-label. However, the effectiveness and safety of Intrarosa for off-label uses, it’s important to follow your healthcare provider’s guidance.

What special precautions should I follow?

When using Intrarosa, there are some important precautions to consider:

  • Hormone-Sensitive Conditions: Intrarosa may be converted into estrogen and testosterone in the body. If you have a history of hormone-sensitive cancers, such as breast cancer or endometrial cancer, or if you have unexplained vaginal bleeding, it is essential to discuss this with your healthcare provider before using Intrarosa.
  • Pre-existing Medical Conditions: Inform your healthcare provider about any pre-existing medical conditions, such as liver problems or abnormal vaginal bleeding, as these may affect the suitability of using Intrarosa.
  • Drug Interactions: Let your healthcare provider know about any medications, supplements, or herbal products you are currently taking, as they may interact with Intrarosa.
  • Pregnancy and Breastfeeding: Intrarosa is not indicated for use during pregnancy or while breastfeeding. Consult your healthcare provider for appropriate alternatives or if you become pregnant or plan to breastfeed while using Intrarosa.
  • Side Effects: Common side effects of Intrarosa may include vaginal discharge, abnormal Pap smear, and changes in vaginal cells. If you experience any concerning or persistent side effects, consult your healthcare provider.

What special dietary instructions should I follow?

There are no specific dietary instructions associated with the use of Intrarosa. You can continue with your regular diet while using this medication. However, it’s generally advisable to maintain a healthy and balanced diet as part of your overall well-being.

What should I do if I forget a dose?

If you forget to take a dose of Intrarosa, take it as soon as you remember. If it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

What side effects can this medication cause?

Like any medication, Intrarosa can potentially cause side effects. Common side effects of Intrarosa may include:

  • Vaginal discharge: Some women may experience an increase in vaginal discharge while using Intrarosa.
  • Vaginal yeast infection: Intrarosa may increase the risk of developing a vaginal yeast infection, which can cause symptoms such as itching, burning, and abnormal discharge.
  • Vulvovaginal candidiasis: In some cases, the use of Intrarosa may lead to vulvovaginal candidiasis, an infection caused by the overgrowth of a yeast called Candida.
  • Headache: Headaches have been reported as a possible side effect of Intrarosa use.
  • Upper respiratory tract infection: Some women may experience symptoms of an upper respiratory tract infection, such as a runny nose, cough, or sore throat.
  • Genital discharge: Intrarosa may cause a discharge from the genital area in some cases.

It is important to note that not all women will experience these side effects, and some may experience different or no side effects at all. If you are prescribed Intrarosa and have concerns about potential side effects, it is best to consult with your healthcare provider, who can provide personalized information and guidance based on your specific medical history and circumstances.

What should I know about storage and disposal of this medication?

  1. Storage:
    • Keep Intrarosa at room temperature, typically between 68°F to 77°F (20°C to 25°C).
    • Store it in a dry place away from excessive heat and moisture.
    • Keep it out of reach of children and pets.
    • Do not use the medication if it has expired or if the packaging is damaged.
  2. Disposal:
    • Dispose of unused or expired Intrarosa medication properly to prevent accidental ingestion by others.
    • Follow any specific disposal instructions provided by your healthcare provider or local regulations.
    • If no specific instructions are given, you can consider using a drug take-back program or consult your pharmacist for guidance.

In case of emergency/overdose

  • If you suspect an overdose or experience severe symptoms after using Intrarosa, immediately seek emergency medical assistance by calling your local emergency number.
  • Overdose symptoms may include nausea, vomiting, dizziness, fainting, or any other unusual or severe reactions.
  • Do not induce vomiting unless instructed to do so by a healthcare professional.

What other information should I know?

  • Inform your healthcare provider about any allergies or sensitivities you may have before starting Intrarosa.
  • Provide a detailed medical history, including any current medications, supplements, or herbal products you are taking.
  • Follow the prescribed dosage and administration instructions carefully.
  • If you miss a dose, take it as soon as you remember. However, if it’s close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
  • Report any new or worsening symptoms to your healthcare provider while using Intrarosa.
  • Attend regular follow-up appointments to evaluate the effectiveness of the treatment and to address any concerns or questions.

Remember, this information is a general guide. Always consult your healthcare provider or pharmacist for specific instructions and advice regarding the storage, disposal, and emergency management of Intrarosa based on your individual circumstances.

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