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Intelence (Generic Etravirine)

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Why is this medication prescribed?

Intelence (etravirine) is prescribed for the treatment of HIV-1 infection in adults and children aged six years and older. It is specifically used in individuals who have developed resistance to other non-nucleoside reverse transcriptase inhibitors (NNRTIs) or who have not responded well to other HIV medications.

The primary reason Intelence is prescribed is to suppress the replication of the HIV virus and reduce the viral load in the body. By doing so, it helps slow down the progression of HIV infection and AIDS, improve immune function, and decrease the risk of developing opportunistic infections and complications associated with HIV.

Intelence is typically used in combination with other antiretroviral drugs, forming a comprehensive treatment regimen known as highly active antiretroviral therapy (HAART) or combination antiretroviral therapy (cART). The combination of different antiretroviral medications helps to target the virus at multiple stages of its replication cycle, enhancing treatment efficacy and reducing the likelihood of drug resistance.

How should this medicine be used?

When using Intelence (etravirine), it is important to follow the instructions provided by your healthcare professional. Here are general guidelines on how Intelence is typically used:

  • Dosage: The dosage of Intelence will be determined by your healthcare provider based on factors such as your age, weight, other medications you are taking, and your overall health condition.
  • Administration: Intelence is taken orally in tablet form. It is usually taken with a meal to enhance its absorption. Swallow the tablet whole with water. Do not crush, chew, or break the tablet unless directed by your doctor.
  • Timing: Take Intelence at the same time(s) every day to maintain consistent levels of the medication in your body. It is important to establish a routine that works for you to ensure you do not miss doses.
  • Other Medications: Intelence is typically used in combination with other antiretroviral drugs as part of a comprehensive treatment regimen. Take all prescribed medications as directed by your healthcare provider.
  • Follow-up: Regularly communicate with your healthcare provider regarding your treatment progress. Attend follow-up appointments, undergo recommended laboratory tests, and discuss any concerns or side effects you may be experiencing.
  • Adherence: It is crucial to take Intelence regularly and exactly as prescribed to maintain its effectiveness. Skipping doses or not following the recommended schedule can reduce the medication’s efficacy and increase the risk of developing drug resistance.
  • Storage: Store Intelence tablets at room temperature, away from moisture and heat. Follow the specific storage instructions provided by the manufacturer or your pharmacist.

It is important to note that these are general guidelines, and individual dosing instructions may vary. Always consult your healthcare provider for specific instructions on how to use Intelence based on your unique circumstances.

Other uses for this medicine

Intelence (etravirine) is primarily used for the treatment of HIV-1 infection in adults and children aged six years and older. Its main purpose is to suppress the replication of the HIV virus and reduce the viral load in the body. Currently, there are no other approved therapeutic uses for Intelence beyond HIV treatment.

What special precautions should I follow?

As for special precautions associated with Intelence, it is important to consider the following:

  • Drug Interactions: Intelence can interact with other medications, including prescription drugs, over-the-counter drugs, and herbal supplements. Inform your healthcare provider about all the medications and supplements you are taking to avoid potential interactions.
  • Allergic Reactions: Some individuals may be hypersensitive or allergic to etravirine or any of the components in Intelence tablets. If you experience signs of an allergic reaction such as rash, itching, swelling, dizziness, or difficulty breathing, seek immediate medical attention.
  • Liver Problems: Intelence can cause liver-related side effects. It is important to inform your healthcare provider if you have a history of liver disease, hepatitis B or C, or if you consume alcohol regularly. Regular monitoring of liver function may be required during treatment.
  • Rash: Skin rash is a common side effect associated with Intelence. Some rashes can be severe and require immediate medical attention. Inform your healthcare provider if you develop a rash while taking Intelence.
  • Pregnancy and Breastfeeding: The use of Intelence during pregnancy or breastfeeding should be discussed with your healthcare provider. The potential risks and benefits need to be evaluated to determine the best course of action.
  • Resistance: Intelence is used in individuals who have developed resistance to other non-nucleoside reverse transcriptase inhibitors (NNRTIs). It is important to take the medication as prescribed and adhere to the recommended treatment regimen to minimize the risk of developing further drug resistance.

These are just a few precautions associated with Intelence, and it is crucial to consult with your healthcare provider or read the medication’s package insert for a comprehensive list of precautions, warnings, and potential side effects.

What special dietary instructions should I follow?

If you have been prescribed Intelence (Etravirine), it is essential to follow your healthcare provider’s instructions regarding its use. Typically, it is recommended to take Intelence with a meal to increase its absorption. This means you should take the medication alongside food. However, please consult your healthcare provider or read the medication’s accompanying literature for specific instructions as they may vary depending on individual circumstances.

What should I do if I forget a dose?

If you happen to forget a dose of Intelence, take it as soon as you remember. However, if it is close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one. It is important to maintain consistent adherence to your medication regimen, so if you frequently forget doses or have concerns about missed doses, it’s best to discuss this with your healthcare provider for further guidance.

What side effects can this medication cause?

Like any medication, Intelence can cause side effects in some individuals. It’s important to note that not everyone will experience these side effects, and the severity and frequency can vary from person to person. Some of the potential side effects of Intelence include:

  • Rash: Skin rashes are the most commonly reported side effect of Intelence. They can range from mild to severe and may be accompanied by itching, redness, or blistering. If you develop a rash while taking Intelence, it is essential to inform your healthcare provider.
  • Nausea and vomiting: Some individuals may experience gastrointestinal symptoms such as nausea and vomiting. These side effects are usually mild and tend to resolve on their own. Taking Intelence with food can help reduce the likelihood of experiencing these symptoms.
  • Diarrhea: Diarrhea is another gastrointestinal side effect that may occur while taking Intelence. It is advisable to stay hydrated and inform your doctor if this side effect becomes severe or persistent.
  • Headache: Headaches are a commonly reported side effect of Intelence. They are typically mild and transient, but if they persist or worsen, it is recommended to consult your healthcare provider.
  • Fatigue: Some individuals may experience tiredness or fatigue while taking Intelence. If this side effect becomes bothersome or affects your daily activities, you should discuss it with your doctor.
  • Abnormal dreams: Intelence has been associated with changes in dreaming patterns, including vivid or abnormal dreams. These dreams are generally harmless but should be mentioned to your healthcare provider if they become excessive or disturbing.
  • Liver problems: In rare cases, Intelence may cause liver problems, including elevated liver enzymes or hepatitis. It is important to undergo regular monitoring of liver function tests while taking Intelence. If you experience symptoms such as yellowing of the skin or eyes, dark urine, or abdominal pain, seek medical attention immediately.

It’s worth noting that this list does not include all possible side effects of Intelence. If you have any concerns or experience any unusual symptoms while taking Intelence, it is crucial to contact your healthcare provider for further evaluation and guidance.

What should I know about storage and disposal of this medication?

  1. Storage of Intelence:
    • Keep Intelence tablets in their original container at room temperature, away from moisture and heat.
    • Avoid storing the medication in the bathroom or any area with excessive humidity.
    • Do not freeze Intelence.
  2. Disposal of Intelence:
    • If you no longer need Intelence or it has expired, follow proper disposal guidelines.
    • You can consult your local pharmacy or healthcare provider for information on medication disposal programs in your area.
    • Do not flush Intelence down the toilet or pour it into drains, as it can contaminate water sources.

In case of emergency/overdose

  • In case of an emergency or suspected overdose, call your local emergency services immediately.
  • Provide them with as much information as possible, including the quantity and strength of the medication taken.
  • If available, bring the Intelence container or packaging with you to the hospital.

What other information should I know?

  • Only take Intelence if it has been prescribed to you by a healthcare professional.
  • Inform your doctor about any other medications, supplements, or herbal products you are taking before starting Intelence, as it may interact with them.
  • Take Intelence exactly as prescribed, at the recommended dosage and schedule.
  • Do not skip doses or stop taking Intelence without consulting your doctor, as it may decrease the effectiveness of the treatment and increase the risk of developing drug resistance.
  • If you miss a dose, take it as soon as you remember, unless it is close to the time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule.
  • It’s important to attend regular check-ups with your healthcare provider to monitor your response to Intelence and assess any potential side effects.

Remember, this information is not exhaustive, and it’s always advisable to consult your healthcare provider or pharmacist for specific instructions and guidance regarding Intelence or any other medication.

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