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Insulin Aspart (rDNA Origin) Injection

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Why is this medication prescribed?

Insulin Aspart (rDNA origin) injection is a medication that is prescribed to individuals with diabetes. It is a rapid-acting insulin analog that is used to help control blood sugar levels in people with diabetes mellitus. Here are the primary reasons why Insulin Aspart may be prescribed:

  • Diabetes type 1: Insulin Aspart is commonly prescribed for individuals with type 1 diabetes. Type 1 diabetes occurs when the body does not produce enough insulin, the hormone responsible for regulating blood sugar. Insulin Aspart is used to replace the insufficient natural insulin and help maintain blood sugar levels within the target range.
  • Diabetes type 2: In some cases, people with type 2 diabetes, a condition characterized by insulin resistance or insufficient insulin production, may also require insulin therapy. Insulin Aspart can be prescribed to manage blood sugar levels when oral medications, lifestyle changes, and other injectable diabetes medications are not effectively controlling blood glucose.
  • Basal-bolus regimen: Insulin Aspart is often used as part of a basal-bolus insulin regimen. This involves combining a long-acting or basal insulin to provide a continuous background insulin level with rapid-acting insulins like Insulin Aspart to cover the blood sugar spikes after meals.
  • Insulin pump therapy: Insulin Aspart is suitable for use in insulin pumps, which are small devices that deliver insulin continuously throughout the day. It allows for precise insulin dosing and flexibility in adjusting the insulin delivery based on individual needs.

How should this medicine be used?

Here are some general guidelines for using Insulin Aspart (rDNA Origin) Injection:

  • Administration: Insulin Aspart (rDNA Origin) is usually injected subcutaneously (under the skin) using a syringe, insulin pen, or an insulin pump. It should not be injected into a vein or muscle unless specifically instructed by your healthcare provider.
  • Dosage: The dosage of Insulin Aspart (rDNA Origin) will vary depending on your individual needs, which may be determined by factors such as your blood sugar levels, diet, exercise, and other medications you may be taking. Your healthcare provider will prescribe the appropriate dosage for you.
  • Timing: Insulin Aspart (rDNA Origin) is a rapid-acting insulin, meaning it starts working quickly and has a shorter duration of action compared to other types of insulin. It is typically taken just before or immediately after meals to help control the rise in blood sugar levels that occurs after eating.
  • Injection Sites: Insulin Aspart (rDNA Origin) injections are usually administered in the fatty tissue just beneath the skin. Common injection sites include the abdomen (around the belly button), thighs, upper arms, or buttocks. It is important to rotate injection sites to prevent skin problems such as lipodystrophy (thickened or pitted skin) from developing.
  • Storage: Insulin Aspart (rDNA Origin) should be stored according to the instructions provided by the manufacturer. Generally, it should be stored in the refrigerator between 36°F and 46°F (2°C to 8°C). Do not freeze the insulin, and avoid exposing it to excessive heat or direct sunlight. Insulin Aspart (rDNA Origin) that is currently being used can be kept at room temperature (between 59°F and 86°F or 15°C and 30°C) for a limited period, usually up to 28 days, but it is essential to consult the specific instructions for your product.
  • Monitoring: Regular monitoring of blood sugar levels is important when using Insulin Aspart (rDNA Origin) to ensure proper dosage adjustment and overall diabetes management. Follow your healthcare provider’s instructions on when and how to check your blood sugar levels.

It is crucial to remember that the information provided here is general, and you should always consult your healthcare provider or the specific instructions provided with your medication for precise guidance on how to use Insulin Aspart (rDNA Origin) Injection. They can provide you with personalized instructions based on your individual needs and circumstances.

Other uses for this medicine

However, it is primarily indicated for the management of diabetes and should be used under the supervision of a healthcare professional. Insulin Aspart (rDNA Origin) Injection is not typically used for other medical conditions or purposes. Its main use is to replace or supplement the insulin produced by the pancreas in individuals with diabetes.

What special precautions should I follow?

As for special precautions, here are some important points to consider:

  • Allergies: Inform your healthcare provider if you have any known allergies to insulin or any of its components. Hypersensitivity reactions to insulin can occur, although they are rare.
  • Dosage and administration: Insulin Aspart (rDNA Origin) Injection should be administered as prescribed by your healthcare provider. It is usually injected subcutaneously (under the skin) using a syringe, insulin pen, or insulin pump. Follow the specific instructions provided by your healthcare professional for proper administration technique.
  • Blood sugar monitoring: Regular blood sugar monitoring is essential when using Insulin Aspart (rDNA Origin) Injection. Monitor your blood glucose levels as directed by your healthcare provider to ensure they stay within the target range.
  • Hypoglycemia: Insulin Aspart (rDNA Origin) Injection may cause low blood sugar levels (hypoglycemia). Symptoms of hypoglycemia include sweating, dizziness, confusion, shaking, and rapid heartbeat. It’s important to be aware of these symptoms and have a plan for treating hypoglycemia, such as carrying a fast-acting source of glucose (e.g., glucose tablets or gel).
  • Hyperglycemia or diabetic ketoacidosis (DKA): In rare cases, insulin therapy, including Insulin Aspart (rDNA Origin) Injection, can lead to high blood sugar levels (hyperglycemia) or a serious condition called DKA. Be vigilant for symptoms of hyperglycemia (increased thirst, frequent urination, blurred vision) or DKA (nausea, vomiting, abdominal pain, fruity breath odor) and seek medical attention if necessary.
  • Drug interactions: Inform your healthcare provider about all the medications you are taking, including prescription, over-the-counter drugs, and supplements. Some medications may interact with insulin, potentially affecting blood sugar control.

Always consult your healthcare provider or diabetes specialist for specific guidance on the use of Insulin Aspart (rDNA Origin) Injection and any precautions or considerations relevant to your individual situation.

What special dietary instructions should I follow?

Regarding dietary instructions for Insulin Aspart (rDNA Origin) Injection, it is generally recommended to follow a balanced and consistent meal plan as advised by your healthcare provider or dietitian. Here are some general guidelines:

  • Carbohydrate consistency: Insulin Aspart is a rapid-acting insulin that helps control blood sugar levels after meals. It is typically taken shortly before or after meals. To optimize its effectiveness, it’s important to consume a consistent amount of carbohydrates with each meal.
  • Carbohydrate counting: If you have been instructed to count carbohydrates, you may need to adjust your insulin dose based on the amount of carbohydrates you plan to consume. Your healthcare provider or dietitian can provide guidance on carbohydrate counting and insulin adjustments.
  • Timing of meals and injections: It’s important to coordinate your meal times and insulin injections to ensure the insulin starts working when your blood sugar rises after a meal. Your healthcare provider will provide specific instructions on when to take your insulin in relation to your meals.

What should I do if I forget a dose?

If you forget to take a dose of Insulin Aspart, here are some general steps to follow:

  • Check your blood sugar: Monitor your blood sugar levels to determine if they are within the target range. If your blood sugar is high, you may need to take corrective action, which could involve taking an additional dose of insulin. However, always consult your healthcare provider for specific instructions based on your individual situation.
  • Take the missed dose as soon as you remember: If you realize you missed a dose, take it as soon as possible. However, if it is close to the time of your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for the missed one.
  • Monitor your blood sugar closely: After missing a dose, monitor your blood sugar levels frequently to ensure they remain within the target range. Contact your healthcare provider if you have concerns or if your blood sugar levels are consistently high or low.

What side effects can this medication cause?

Insulin Aspart (rDNA Origin) is a fast-acting insulin used to control blood sugar levels in individuals with diabetes. Like any medication, it can have side effects. Common side effects of Insulin Aspart may include:

  • Hypoglycemia: Low blood sugar is the most common side effect of insulin. Symptoms may include dizziness, shakiness, sweating, confusion, headache, and weakness.
  • Hypoglycemia unawareness: In some cases, individuals may experience a reduced ability to sense the early signs of low blood sugar, which can be dangerous if left untreated.
  • Injection site reactions: Redness, itching, pain, or swelling at the injection site can occur. These reactions are usually mild and temporary.
  • Lipodystrophy: Long-term use of insulin injections in the same area may lead to changes in the fatty tissue under the skin, causing lumps or dents at the injection site.
  • Weight gain: Insulin therapy can contribute to weight gain in some individuals. This can occur due to improved blood sugar control, increased appetite, or fluid retention.
  • Allergic reactions: While rare, some individuals may develop an allergic reaction to insulin aspart. Signs of an allergic reaction include itching, rash, swelling, dizziness, or difficulty breathing. Seek immediate medical attention if these symptoms occur.

It’s important to note that this is not an exhaustive list of all possible side effects. Some individuals may experience other side effects. It’s recommended to consult a healthcare professional or refer to the medication’s package insert for comprehensive information about potential side effects.

What should I know about storage and disposal of this medication?


  • Insulin Aspart should be stored in the refrigerator between 36°F to 46°F (2°C to 8°C). Do not freeze it. Freezing can damage the insulin and make it ineffective.
  • Keep the insulin away from direct sunlight and extreme temperatures. Do not store it in the freezer, near a heating source, or in the glove compartment of a car.
  • If the insulin has been frozen or exposed to extreme temperatures, it should be discarded, as it may no longer be effective.


  • When discarding used insulin aspart injection pens, needles, or syringes, follow local regulations and guidelines. Do not dispose of them in regular household trash.
  • Some areas may have specific sharps disposal programs or guidelines for safe disposal of medical waste. Check with your healthcare provider, local pharmacy, or municipal health department for proper disposal instructions.

In case of emergency/overdose

  • In case of an emergency or suspected overdose, immediately contact your healthcare provider, local emergency services, or go to the nearest emergency room.
  • Signs of an insulin overdose may include confusion, dizziness, shakiness, sweating, rapid heartbeat, seizures, or unconsciousness. If you suspect an overdose, it’s essential to seek medical help immediately.
  • It may be helpful to carry a glucagon emergency kit with you. Glucagon is a hormone that can be injected to rapidly increase blood sugar levels in cases of severe low blood sugar (hypoglycemia) caused by an insulin overdose. Your healthcare provider can prescribe a glucagon kit and provide instructions on how to use it.

What other information should I know?

  • Insulin Aspart is for subcutaneous injection (under the skin) and should not be administered intravenously.
  • Always check the expiration date on the insulin aspart vial or pen before use. Expired insulin should not be used as it may not be effective or safe.
  • Keep track of your insulin supply and refill it before running out to ensure continuity of your diabetes management.
  • Regularly monitor your blood sugar levels as directed by your healthcare provider and adjust your insulin dosage accordingly.
  • Inform your healthcare provider about any other medications you are taking as they may interact with insulin aspart.

It’s important to consult with your healthcare provider or pharmacist for specific instructions and guidance regarding the storage, disposal, and emergency procedures for Insulin Aspart (rDNA Origin) based on your individual needs and circumstances.

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