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Humalog Mix75/25 (Generic Insulin Lispro Injection)

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Why is this medication prescribed?

Humalog Mix75/25 is a prescription medication that is primarily used to manage blood sugar levels in people with diabetes. It is a mixture of two types of insulin: 75% insulin lispro protamine suspension and 25% insulin lispro injection.

Humalog Mix75/25 is commonly prescribed for individuals with type 2 diabetes who require insulin therapy. It can also be used for people with type 1 diabetes who may benefit from this particular insulin mixture. It is usually prescribed when other forms of insulin or diabetes medications alone are not adequately controlling blood sugar levels.

How should this medicine be used?

The specific dosage and administration instructions for Humalog Mix75/25 should be provided by a healthcare professional or a doctor, as they will tailor the treatment to each individual’s needs. Generally, the medication is injected subcutaneously (under the skin) using an insulin syringe, pen, or pump.

The timing and frequency of injections will depend on the individual’s blood sugar levels, meal patterns, and other factors. It is typically administered before meals to help control the rise in blood sugar that occurs after eating.

Other uses for this medicine

Humalog Mix75/25 is primarily used for managing blood sugar levels in individuals with diabetes. However, it is important to note that the use of Humalog Mix75/25 for any other purposes should be determined and prescribed by a healthcare professional. They will evaluate your specific medical condition and determine the most appropriate treatment options.

What special precautions should I follow?

When using Humalog Mix75/25, it is crucial to take certain precautions to ensure safe and effective use. Here are some general precautions to keep in mind:

  • Hypoglycemia (low blood sugar): Humalog Mix75/25 can cause low blood sugar levels, especially if the dose is too high or if you have changes in your diet, physical activity, or other medications. It is important to monitor your blood sugar regularly and be aware of the signs and symptoms of hypoglycemia. Always carry a source of fast-acting sugar, such as glucose tablets or juice, to treat low blood sugar if needed.
  • Hyperglycemia (high blood sugar) and diabetic ketoacidosis (DKA): Monitor your blood sugar levels closely to ensure they are within the target range. If your blood sugar remains consistently high or if you experience symptoms of hyperglycemia (excessive thirst, frequent urination, blurred vision) or DKA (high ketones in the blood, fruity breath odor, nausea, vomiting), seek medical attention immediately.
  • Allergic reactions: Some individuals may be allergic to Humalog Mix75/25 or its components. If you experience symptoms of an allergic reaction, such as rash, itching, swelling, dizziness, or difficulty breathing, seek immediate medical attention.
  • Other medical conditions: Inform your healthcare provider about any other medical conditions you have, including liver or kidney problems, as it may affect the use of Humalog Mix75/25.
  • Medication interactions: Inform your healthcare provider about all the medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements. Some medications can interact with Humalog Mix75/25, affecting its effectiveness or increasing the risk of side effects.

What special dietary instructions should I follow?

Humalog Mix75/25 is a medication used to manage diabetes. It is a mixture of insulin lispro protamine and insulin lispro, which helps control blood sugar levels. While taking Humalog Mix75/25, it is important to follow certain dietary instructions and guidelines. However, please note that it is always best to consult with your healthcare provider for specific instructions tailored to your individual needs. Here are some general recommendations:

  • Consistency: Try to maintain a consistent eating schedule with regular meal times to help manage your blood sugar levels effectively. Skipping meals or having irregular eating patterns can affect the effectiveness of the medication.
  • Balanced diet: Focus on consuming a well-balanced diet that includes a variety of nutrient-rich foods such as fruits, vegetables, whole grains, lean proteins, and healthy fats. This can help provide a steady release of glucose into your bloodstream.
  • Carbohydrate management: Since Humalog Mix75/25 is specifically designed to control post-meal blood sugar spikes, it is important to monitor your carbohydrate intake. Consult with a registered dietitian or healthcare provider to determine the appropriate amount of carbohydrates to include in each meal.
  • Avoid excessive sugar: Minimize your intake of sugary foods and beverages, as they can cause rapid increases in blood sugar levels. Opt for healthier alternatives or consume sugar in moderation.
  • Consistent alcohol consumption: If you consume alcohol, it is crucial to do so in moderation and with caution. Alcohol can affect blood sugar levels, so it’s important to monitor your levels closely and discuss alcohol consumption with your healthcare provider.

What should I do if I forget a dose?

Regarding missed doses of Humalog Mix75/25, it is important to try and adhere to your prescribed dosing schedule. However, if you happen to forget a dose, follow these general guidelines:

  • Check your blood sugar: Monitor your blood sugar levels to assess your current situation. If your levels are within a safe range, you may not need to take immediate action. However, if your blood sugar is elevated or if you experience symptoms of high blood sugar, consult with your healthcare provider for guidance.
  • Take the missed dose as soon as you remember: If you realize that you missed a dose, take it as soon as possible unless it is close to the time for your next scheduled dose. Do not double up on doses to make up for the missed one.
  • Consult your healthcare provider: If you are unsure about what to do or if you frequently forget doses, it is crucial to contact your healthcare provider. They can provide specific instructions and help you establish a routine to minimize missed doses.

What side effects can this medication cause?

Humalog Mix75/25 is a combination medication containing 75% insulin lispro protamine suspension and 25% insulin lispro injection. It is used to control blood sugar levels in people with diabetes. Like any medication, Humalog Mix75/25 can cause side effects. Some possible side effects associated with its use include:

  • Injection site reactions: Insulin injections can sometimes cause local reactions at the injection site, such as redness, swelling, or itching. These reactions are usually mild and temporary.
  • Allergic reactions: Although rare, some people may experience allergic reactions to Humalog Mix75/25. Signs of an allergic reaction can include rash, itching, shortness of breath, wheezing, or swelling of the face, lips, tongue, or throat. If you experience these symptoms, seek immediate medical attention.
  • Weight gain: Insulin therapy, including Humalog Mix75/25, can sometimes lead to weight gain. This is because insulin promotes the storage of glucose as fat. It’s important to maintain a healthy diet and exercise regularly to manage your weight while using insulin.
  • Edema: Some individuals may experience fluid retention and swelling, known as edema, as a side effect of insulin therapy. If you notice swelling in your hands, feet, or ankles, inform your healthcare provider.
  • Hypokalemia: Rarely, insulin treatment can cause low potassium levels in the blood, known as hypokalemia. This can lead to symptoms such as muscle weakness, fatigue, and irregular heart rhythm. Regular monitoring of electrolyte levels may be necessary, especially if you have other risk factors for hypokalemia.
  • Hypoglycemia: This is the most common side effect of insulin therapy. It occurs when blood sugar levels drop too low. Symptoms of hypoglycemia can include dizziness, shakiness, sweating, confusion, headache, and hunger. It’s important to monitor your blood sugar levels regularly and be aware of the signs of low blood sugar.

What should I know about storage and disposal of this medication?

  • Storage: Humalog Mix75/25 should be stored in the refrigerator at a temperature between 36°F and 46°F (2°C and 8°C). Do not freeze it. Keep the vials or pens away from direct heat and light. Once opened, the vials or pens can be stored at room temperature (between 59°F and 86°F or 15°C and 30°C) for up to 28 days. Discard any unused portion after 28 days. Do not use Humalog Mix75/25 if it has been frozen, exposed to excessive heat, or if it has changed color or appearance. Inspect the medication before each use, and if you notice any abnormalities, consult your pharmacist or healthcare provider.
  • Disposal: Safely dispose of used needles, syringes, and empty vials or pens in a puncture-resistant container. This helps prevent accidental needle sticks and ensures proper disposal. You can ask your healthcare provider or pharmacist about proper disposal methods in your area.In case of emergency/overdose

What other information should I know?

  • Use Humalog Mix75/25 exactly as prescribed by your healthcare provider. Do not change your dose or stop using it without consulting them.
  • Inform your healthcare provider about all medications, including over-the-counter drugs, supplements, and herbal products, that you are taking. Some medications can interact with Humalog Mix75/25 and affect its effectiveness or increase the risk of hypoglycemia or hyperglycemia.
  • Regularly monitor your blood sugar levels as directed by your healthcare provider and follow your prescribed meal plan and exercise routine.
  • Inform healthcare professionals (such as doctors, dentists, or emergency responders) about your use of Humalog Mix75/25 before undergoing any procedures or treatments.
  • Keep an identification card or wear a medical alert bracelet or necklace stating that you have diabetes and require insulin.

Remember, it is crucial to consult your healthcare provider or pharmacist for specific instructions and any additional information regarding the storage, disposal, and emergency management of Humalog Mix75/25, as they can provide personalized guidance based on your individual needs and medical history.

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