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Why is this medication prescribed?

Glimepiride is prescribed primarily for the management of type 2 diabetes mellitus. Type 2 diabetes is a condition characterized by high blood sugar levels resulting from the body’s inability to effectively use insulin or to produce enough insulin. Glimepiride belongs to a class of medications called sulfonylureas, which work by stimulating the pancreas to release more insulin and by increasing the body’s sensitivity to insulin. By helping to lower blood sugar levels, Glimepiride helps control symptoms of diabetes and reduces the risk of long-term complications associated with uncontrolled diabetes, such as cardiovascular disease, kidney damage, nerve damage, and eye problems. It is typically used in combination with other treatments such as diet and exercise, and sometimes with other diabetes medications, to achieve optimal blood sugar control.

How should this medicine be used?

Here’s how Glimepiride is typically used:

  • Dosage: The dosage of Glimepiride varies depending on factors such as the patient’s medical condition, response to treatment, and other medications they may be taking. Your doctor will prescribe the appropriate dosage for you.
  • Administration: Glimepiride comes as a tablet to take by mouth, with or without food. It is typically taken once daily, usually with breakfast or the first main meal of the day. Follow your doctor’s instructions carefully regarding when and how to take Glimepiride.
  • Regular monitoring: It’s important to monitor your blood sugar levels regularly while taking Glimepiride, as directed by your doctor. This helps ensure that the medication is effectively controlling your diabetes and allows adjustments to be made if necessary.
  • Do not skip doses: Take Glimepiride exactly as prescribed by your doctor. Do not skip doses or take more than the prescribed amount, as this can increase the risk of side effects and complications.
  • Caution with alcohol: Avoid excessive alcohol consumption while taking Glimepiride, as it can increase the risk of low blood sugar levels (hypoglycemia).
  • Follow-up appointments: Attend all scheduled follow-up appointments with your doctor to monitor your response to Glimepiride and to address any concerns or adjustments needed.
  • Lifestyle modifications: Along with taking Glimepiride, it’s essential to maintain a healthy lifestyle, including a balanced diet, regular exercise, and weight management, to effectively manage type 2 diabetes.

As with any medication, it’s important to discuss any questions or concerns you have about Glimepiride with your doctor or healthcare provider. They can provide personalized guidance based on your individual medical history and needs.

Other uses for this medicine

While Glimepiride is primarily prescribed for the management of type 2 diabetes mellitus, there are no other approved medical uses for Glimepiride outside of its role in treating diabetes. It is essential to use Glimepiride only as prescribed by your healthcare provider for the approved indication.

What special precautions should I follow?

Regarding special precautions for Glimepiride, here are some key points to consider:

  • Hypoglycemia (low blood sugar): Glimepiride can cause hypoglycemia, especially if not taken as directed or if there are sudden changes in diet, exercise, or medication regimen. Symptoms of hypoglycemia include shakiness, dizziness, sweating, hunger, confusion, irritability, fast heartbeat, and fainting. It’s essential to monitor blood sugar levels regularly and be aware of the signs and symptoms of hypoglycemia. Always carry a source of glucose (such as glucose tablets or gel) to treat low blood sugar if needed.
  • Liver and kidney function: Glimepiride is primarily metabolized by the liver and excreted by the kidneys. Special caution is advised in patients with impaired liver or kidney function, as they may be at increased risk of experiencing adverse effects. Your doctor may need to adjust the dosage of Glimepiride accordingly in such cases.
  • Drug interactions: Glimepiride may interact with other medications, including certain antibiotics, antifungal medications, beta-blockers, and some antidepressants. These interactions can affect blood sugar levels and the effectiveness of Glimepiride. Always inform your doctor about all medications, supplements, and herbal products you are taking to avoid potential interactions.
  • Allergic reactions: Some people may be allergic to Glimepiride or other sulfonylureas. If you experience symptoms of an allergic reaction, such as rash, itching, swelling, or difficulty breathing, seek medical attention immediately.
  • Pregnancy and breastfeeding: Glimepiride may not be recommended during pregnancy or breastfeeding, as it can cross the placenta and pass into breast milk. It’s essential to discuss the potential risks and benefits with your doctor if you are pregnant or breastfeeding while taking Glimepiride.
  • Alcohol: Limit alcohol consumption while taking Glimepiride, as it can increase the risk of hypoglycemia.

Always follow your doctor’s instructions and recommendations regarding the use of Glimepiride, and do not hesitate to ask any questions or raise concerns about its use.

What special dietary instructions should I follow?

Regarding special dietary instructions:

  • Consistent Meal Timing: Try to maintain a consistent schedule for your meals while taking Glimepiride. This can help stabilize your blood sugar levels.
  • Balanced Diet: Follow a balanced diet that includes a variety of foods from different food groups, including fruits, vegetables, whole grains, lean proteins, and healthy fats. Your healthcare provider or a registered dietitian can provide personalized dietary recommendations based on your individual needs and preferences.
  • Carbohydrate Monitoring: Be mindful of your carbohydrate intake, as carbohydrates can affect your blood sugar levels. Your healthcare provider or dietitian can help you determine an appropriate carbohydrate intake for your dietary plan.

What should I do if I forget a dose?

If you forget a dose of Glimepiride:

  • Take the Missed Dose ASAP: If you forget to take a dose of Glimepiride, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.
  • Monitor Blood Sugar Levels: Keep an eye on your blood sugar levels after missing a dose, as skipping doses can affect your blood sugar control. If you experience any unusual symptoms or notice significant changes in your blood sugar levels, contact your healthcare provider for guidance.
  • Prevent Recurrence: To help prevent missing doses in the future, consider setting reminders or alarms to take your medication at the same time each day.

What side effects can this medication cause?

Glimepiride, like any medication, can cause side effects in some individuals. Common side effects of Glimepiride may include:

  • Hypoglycemia: Low blood sugar (hypoglycemia) is the most common side effect of Glimepiride. Symptoms may include shakiness, dizziness, sweating, hunger, confusion, irritability, fast heartbeat, and fainting.
  • Weight gain: Some people may experience weight gain while taking Glimepiride.
  • Gastrointestinal effects: This may include nausea, vomiting, diarrhea, or abdominal discomfort.
  • Allergic reactions: Although rare, some individuals may experience allergic reactions to Glimepiride, which can manifest as rash, itching, swelling, or difficulty breathing. Seek medical attention immediately if you experience any signs of an allergic reaction.
  • Skin reactions: Some people may experience skin reactions such as itching, redness, or rash.
  • Liver function abnormalities: Glimepiride may affect liver function in some individuals, leading to abnormalities in liver enzyme levels. Regular monitoring of liver function may be recommended in certain cases.
  • Vision changes: Blurred vision or changes in vision have been reported by some individuals taking Glimepiride.
  • Low sodium levels (hyponatremia: Glimepiride may rarely cause low sodium levels in the blood, which can manifest as symptoms such as headache, confusion, weakness, seizures, or coma.
  • Hematologic effects: In rare cases, Glimepiride may cause changes in blood cell counts, such as decreased platelet count (thrombocytopenia) or decreased red blood cell count (anemia).
  • Sun sensitivity: Some individuals may experience increased sensitivity to sunlight (photosensitivity) while taking Glimepiride.

It’s essential to report any unusual or bothersome side effects to your healthcare provider promptly. They can help determine whether the side effects are related to Glimepiride and provide guidance on how to manage them. Additionally, if you experience symptoms of severe hypoglycemia or allergic reaction, seek medical attention immediately.

What should I know about storage and disposal of this medication?

Storage and disposal of Gleostine:

  • Storage: Store Glimepiride at room temperature away from moisture, heat, and light. Keep it out of the reach of children and pets.
  • Disposal: Dispose of expired or unused Glimepiride safely according to local regulations or as instructed by your healthcare provider or pharmacist. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Proper disposal helps prevent environmental contamination and accidental ingestion by others.

In case of emergency/overdose

In case of overdose or emergency, such as severe hypoglycemia, contact emergency medical services (911 in the United States) or a poison control center immediately. Symptoms of Glimepiride overdose may include confusion, extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, and seizure.

What other information should I know?

  • Inform all healthcare providers (doctors, dentists, pharmacists) that you are taking Glimepiride before undergoing any medical procedures or starting new medications.
  • Attend regular follow-up appointments with your healthcare provider to monitor your blood sugar levels and assess the effectiveness and safety of Glimepiride.
  • Carry identification indicating that you have diabetes and are taking Glimepiride, especially if you are at risk of hypoglycemia.
  • Avoid skipping meals or delaying meals while taking Glimepiride to reduce the risk of hypoglycemia.
  • Be aware of the signs and symptoms of both high and low blood sugar levels and know how to respond appropriately.
  • Inform your healthcare provider if you experience any new or unusual symptoms while taking Glimepiride.

Always follow your healthcare provider’s instructions and recommendations regarding the use of Glimepiride and do not hesitate to ask any questions or seek clarification about its use, storage, disposal, or emergency procedures.

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