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Gimoti (Generic Metoclopramide Nasal Spray)

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You can get tardive dyskinesia, a muscular condition brought on by using metoclopramide nasal spray. If you have tardive dyskinesia, you will move your muscles in odd ways, particularly the muscles in your face. These movements won’t stop or be under your control. Even if you quit using the metoclopramide nasal spray, tardive dyskinesia could persist. The likelihood that you will experience tardive dyskinesia increases the longer you take metoclopramide. As a result, your doctor will probably advise you to stop using metoclopramide products after 12 weeks. Additionally, having diabetes, being elderly, being a woman, or taking medicine for a mental disease all increase your risk of developing tardive dyskinesia. If you have any uncontrollable bodily movements, including lip-smacking, mouth puckering, chewing, frowning, scowling, sticking out your tongue, blinking, eye motions, or trembling your arms or legs, call your doctor right away.

The manufacturer’s patient information sheet (Medication Guide) will be sent to you by your doctor or pharmacist when you start using metoclopramide nasal spray and each time you get a prescription refill. If you have any questions, carefully read the material and contact your doctor or pharmacist.

The risks of using metoclopramide nasal spray should be discussed with your doctor.

Why is this medication prescribed?

Gimoti is a prescription medication that contains the active ingredient metoclopramide. It is available as a nasal spray and is indicated for the treatment of acute and recurrent diabetic gastroparesis in adults. Gastroparesis is a condition that affects the normal movement of the muscles in the stomach, leading to delayed emptying of the stomach contents.

Gimoti works by increasing the movement of the stomach muscles, thereby improving gastric emptying and reducing symptoms such as nausea, vomiting, and feelings of fullness.

How should this medicine be used?

The specific instructions for using Gimoti nasal spray should be provided by your healthcare provider or as indicated in the medication’s prescribing information. It is important to follow their guidance carefully. Generally, the nasal spray is administered in one nostril while the other nostril is closed. The dose and frequency of administration will be determined by your healthcare professional based on your individual needs.

Other uses for this medicine

Gimoti (metoclopramide nasal spray) is primarily prescribed for the treatment of acute and recurrent diabetic gastroparesis in adults. However, it is worth noting that healthcare providers may sometimes prescribe medications for off-label uses, which means using a drug for a condition or purpose other than the one for which it has been approved by regulatory authorities.

What special precautions should I follow?

Regarding special precautions and instructions for using Gimoti, it is crucial to follow the guidance provided by your healthcare professional and carefully read the medication’s prescribing information. Here are some general precautions and considerations:

  • Administration: Gimoti is administered as a nasal spray. Follow the specific instructions provided by your healthcare provider or as indicated in the prescribing information.
  • Dosage: Use Gimoti exactly as prescribed by your doctor. Do not exceed the recommended dosage or change the frequency of use without consulting your healthcare provider.
  • Allergies: Inform your doctor about any known allergies or sensitivities to metoclopramide or any other medications. If you experience signs of an allergic reaction, such as hives, itching, difficulty breathing, or swelling of the face, lips, tongue, or throat, seek medical attention immediately.
  • Side Effects: Like any medication, Gimoti can cause side effects. Common side effects may include headache, nasal congestion, nasal discomfort, and increased blood pressure. However, individual experiences may vary. Contact your doctor if you experience any unusual or bothersome side effects.
  • Interactions: Inform your healthcare provider about all the medications, supplements, and herbal products you are currently taking, as certain drugs can interact with Gimoti and affect its effectiveness or increase the risk of side effects.
  • Medical Conditions: Inform your doctor about any existing medical conditions you have, such as kidney or liver problems, Parkinson’s disease, epilepsy, or a history of depression or other mental health disorders. These conditions may affect the use of Gimoti or require special monitoring.

What special dietary instructions should I follow?

Gimoti is a prescription medication that contains the active ingredient metoclopramide. It is primarily used to treat symptoms of gastroparesis, a condition that affects the movement of the stomach muscles.

What should I do if I forget a dose?

Regarding missed doses, it’s generally recommended to take the missed dose as soon as you remember. However, if it is close to the time for your next scheduled dose, you should skip the missed dose and resume your regular dosing schedule. It’s important not to take a double dose to make up for a missed one.

What side effects can this medication cause?

Gimoti, which contains the active ingredient metoclopramide, may cause several side effects. The most common side effects associated with Gimoti include:

  • Headache
  • Fatigue or drowsiness
  • Dizziness or lightheadedness
  • Restlessness or anxiety
  • Nausea or vomiting
  • Diarrhea or constipation
  • Abdominal pain or discomfort
  • Changes in appetite

These side effects are generally mild and may subside as your body adjusts to the medication. However, if any of these side effects persist or worsen, it is important to contact your healthcare provider.

There are some less common but potentially serious side effects associated with metoclopramide, and if you experience any of the following, you should seek medical attention immediately:

  • Movement disorders, such as uncontrollable muscle movements, tremors, or spasms
  • Irregular or fast heartbeat
  • Signs of an allergic reaction, such as rash, itching, swelling, severe dizziness, or difficulty breathing

It’s important to note that this is not an exhaustive list of side effects, and other side effects may occur. If you have any concerns about the side effects of Gimoti, it is advisable to consult with your healthcare provider or pharmacist for more detailed and personalized information.

What should I know about storage and disposal of this medication?


  • Follow the storage instructions provided by your healthcare provider or pharmacist. Generally, Gimoti should be stored at room temperature, away from excessive heat, moisture, and direct sunlight.
  • Keep the medication in its original packaging to protect it from light and moisture.
  • Store Gimoti out of the reach of children and pets to prevent accidental ingestion.


  • Do not keep expired or unused Gimoti tablets. It is essential to properly dispose of them.
  • Check with your pharmacist or local waste disposal authority about specific guidelines for medication disposal in your area. Some locations may have specific instructions or programs in place.
  • If no specific instructions are available, it is generally recommended to dispose of medications by mixing them with an undesirable substance (e.g., coffee grounds, kitty litter) in a sealed plastic bag and placing it in the household trash.
  • Remove any personal information from the medication packaging before disposal.

In case of emergency/overdose

If you experience an emergency or suspect an overdose of Gimoti, it is crucial to seek immediate medical attention. Contact your local emergency services or go to the nearest emergency room. In case of overdose, symptoms may include drowsiness, confusion, restlessness, involuntary movements, tremors, and seizures. Be sure to inform the medical professionals about the medication you have taken and the dosage.

What other information should I know?

Here are some other important points to consider:

  • Usage: Take Gimoti exactly as prescribed by your healthcare provider. Follow the recommended dosage and do not take more or less of the medication without consulting your doctor.
  • Precautions: Inform your healthcare provider about any allergies you may have, as well as any other medications, supplements, or herbal products you are currently taking. Some medications may interact with Gimoti, so it is important to disclose your complete medical history.
  • Side effects: Like any medication, Gimoti can cause side effects. Common side effects may include headache, dizziness, fatigue, diarrhea, and changes in mood. If you experience any severe or persistent side effects, contact your healthcare provider.
  • Medical conditions: Discuss with your doctor if you have a history of depression, Parkinson’s disease, epilepsy, or any other medical conditions, as Gimoti may not be suitable for you.
  • Pregnancy and breastfeeding: Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. It is important to weigh the potential benefits and risks of using Gimoti during these periods.

Please note that the information provided here is for general knowledge and should not replace the specific instructions and advice given by your healthcare provider.

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