Nonsteroidal anti-inflammatory drugs (NSAIDs) other than aspirin, such flurbiprofen, may increase the chance of having a heart attack or stroke compared to those who do not take them. These occurrences have the potential to be fatal and come about suddenly. For those who use NSAIDs often, this risk can be increased. If you’ve had a heart attack recently, avoid taking an NSAID like flurbiprofen unless your doctor specifically instructs you to. Inform your doctor if you smoke, have high cholesterol, high blood pressure, or diabetes, or if you or anybody in your family has ever experienced any of these conditions. You should also mention any history of heart disease, a heart attack, or a stroke. If you suffer any of the following symptoms, seek emergency medical attention right away: chest pain, shortness of breath, weakness on one side or area of the body, or slurred speech.

Flurbiprofen shouldn’t be taken shortly before or right after having a coronary artery bypass graft (CABG; a form of cardiac surgery).

NSAIDs, including flurbiprofen, can result in stomach or intestine ulcers, bleeding, or holes. These issues can arise at any point during therapy, without any prior symptoms, and they have the potential to be fatal. Long-term NSAID users, the elderly, those in poor health, and those who consume substantial amounts of alcohol while taking flurbiprofen may be at higher risk. Inform your physician if you use any of the following drugs: oral steroids such dexamethasone, methylprednisolone (Medrol), and prednisone (Rayos); anticoagulants (‘blood thinners’) like warfarin (Coumadin, Jantoven); aspirin; other NSAIDs like ibuprofen (Advil, Motrin), and naproxen (Aleve, Naprosyn); selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine (Prozac, Sarafem, Selfemra, in Symbyax), citalopram (Celexa), fluoxetine (Brisdelle, Paxil, Pexeva), fluvoxamine (Luvox), and sertraline (Zoloft); or SNRIs (serotonin norepinephrine reuptake inhibitors), which include duloxetine (Cymbalta), desvenlafaxine (Khedezla), and venlafaxine (Effexor XR). Additionally, let your doctor know if you currently have or have ever had stomach or intestinal bleeding, ulcers, or any other bleeding disorders. Call your doctor and stop taking flurbiprofen if any of the following symptoms appear: stomach pain, heartburn, bloody or coffee-ground-looking vomit, blood in the stool, or dark, tarry stools.

Keep all of your appointments with your physician and the lab. Your doctor will closely monitor your symptoms and probably request a few tests to determine how flurbiprofen is affecting your body. Inform your physician about your feelings so that they can prescribe the ideal dosage of medication to cure your problem with the least chance of negative side effects.

The manufacturer’s patient information sheet (Medication Guide) will be sent to you by your doctor or pharmacist when you start taking flurbiprofen and at each time your prescription is renewed. If you have any questions, carefully read the material and contact your doctor or pharmacist. To obtain the Medication Guide, you can also go to the Food and Drug Administration (FDA) website or the manufacturer’s website.

Flurbiprofen is used to treat rheumatoid arthritis (arthritis brought on by swelling of the joint lining) and osteoarthritis (arthritis brought on by a breakdown of the lining of the joints), both of which are types of arthritis. The class of drugs known as NSAIDs includes flurbiprofen. It functions by preventing the body from producing a chemical that causes discomfort, fever, and inflammation.

Flurbiprofen is available as an oral tablet. Typically, it is consumed two to four times a day. Flurbiprofen should be taken every day at roughly the same time. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Flurbiprofen should be taken as prescribed. Never take it in larger or less amounts or more frequently than directed by your doctor.

Ankylosing spondylitis, an arthritis that usually affects the spine, is similarly managed with flurbiprofen.

Ask your doctor or pharmacist for more details if you’re interested in using this drug for any other conditions.

Before taking flurbiprofen,

• Inform your doctor and pharmacist if you have any allergies to aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), other NSAIDs, other drugs, or any of the components in flurbiprofen tablets. Get the components list from your doctor or pharmacist.
• Inform your doctor and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are currently taking or intend to use. Mention the medications listed in the IMPORTANT WARNING section as well as any of the following: angiotensin-converting enzyme (ACE) inhibitors such captopril, benazepril (Lotensin, in Lotrel), moexipril (Univasc), perindopril (Aceon, in Prestalia), quinapril (Accupril, in Quinaretic), ramipril (Altace), and trandolapril (Mavik, in Tarka); Angiotensin receptor blockers (ARBs) include losartan (Cozaar, Hyzaar), irbesartan (Avapro, in Avalide), candesartan (Atacand, in Atacand HCT), eprosartan (Teveten), and azilsartan (Edarbi, in Edarbyclor), olmesartan (Benicar, Azor, Benicar HCT, Tribenzor), telmisartan (Micardis, Micardis HCT, Twynsta), and valsartan (Exforge HCT); beta blockers like atenolol (Tenormin, Tenoretic), metoprolol (Lopressor, Toprol XL, in Dutoprol), labetalol (Trandate), nadolol (Corgard, in Corzide), propranolol (Hemangeol, Inderal, Innopran), lithium (Lithobid), and methotrexate (Otrexup, Rasuvo, Trexall) are examples of medications. Your medicine doses could need to be adjusted, or your doctor might need to keep a closer eye out for any side effects.
• Inform your physician if you now have or have ever had asthma, particularly if you also suffer from frequent stuffy or runny nose, nasal polyps (swelling of the nasal lining), heart failure, swelling of the hands, feet, ankles, or lower legs, or liver or kidney problems.
• Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. If flurbiprofen is consumed after 20 weeks of pregnancy, it may harm the fetus and complicate delivery. Unless specifically instructed to do so by your doctor, avoid taking flurbiprofen during or after the first 20 weeks of pregnancy. Call your doctor if you become pregnant while taking flurbiprofen.
• Inform your doctor or dentist that you are taking flurbiprofen if you are undergoing surgery, including dental surgery.

Keep eating normally unless your doctor instructs you otherwise.

If you miss a dosage, take it as soon as you recall. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. To make up for a missing dose, do not take a second one.

Flurbiprofen could have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

• Headache
• Anxiousness or jitters
• Depression
• Memory issues
• Region of your body that you are unable to control shakes
• Having trouble falling or staying asleep
• Vomiting
• Gas
• Constipation
• Diarrhea
• Clogged nose
• Hearing ringing

Some side effects can be serious. If you experience any of the following symptoms, or those listed in the IMPORTANT WARNING section, call your doctor immediately. Do not take any more flurbiprofen until you speak to your doctor.

• Vision changes (blurriness, trouble seeing)
• Rise in weight without cause
• Respiratory issues or lack of breath
• Abdomen, ankles, foot, or leg swelling
• Fever
• Blisters
• Rash
• Itching
• Hives
• Eyes, face, lips, tongue, throat, or hands swelling
• Breathing or swallowing challenges
• Light skin
• Rapid heart rate
• Extreme fatigue
• Uncommon bruising or bleeding
• Not enough energy
• Nausea
• Reduced appetite
• Stomach ache in the top right corner
• Flu-like signs
• Eyes or skin that have a yellow tint
• Urine that is hazy, discolored, or bloody
• Back ache
• Uncomfortable or challenging urinating

Other negative effects of flurbiprofen are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online at http://www.fda.gov/Safety/MedWatch or by phone at 1-800-332-1088 if you have a serious side event.

Keep this medication tightly closed in the original container and out of the reach of children. Keep it at room temperature and out of the bathroom and other places with excessive heat and moisture.

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.http://www.upandaway.org

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilizing a medicine take-back program is the best way to get rid of your medication. To find out about take-back programs in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back program, see the FDA’s Safe Disposal of Medicines website at http://goo.gl/c4Rm4p for additional information.

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

Overdose symptoms could include:

• Not enough energy
• Drowsiness
• Nausea
• Vomiting
• Abdominal pain
• Tarry, dark, or bloody stools
• Vomit that is reddish-colored or resembles coffee grounds
• Having trouble breathing
• Coma (a temporary loss of consciousness)

No one else should take your medication. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.