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Fluotrex (Generic Fluocinolone Topical)

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Why is this medication prescribed?

Fluotrex, containing fluocinolone acetonide, is prescribed for various skin conditions characterized by inflammation, itching, and redness. These conditions may include eczema, psoriasis, dermatitis, allergic reactions, and other inflammatory skin disorders.

How should this medicine be used?

Here’s how Fluotrex 0.01% Cream is typically used:

  • Clean the Affected Area: Before applying Fluotrex, clean and dry the affected area of the skin thoroughly.
  • Apply a Thin Layer: Apply a thin layer of Fluotrex cream to the affected area(s) of the skin. Gently rub the cream into the skin until it is absorbed.
  • Wash Hands: After applying Fluotrex, wash your hands unless you are treating your hands.
  • Frequency of Use: The frequency of application will depend on the severity of your condition and your doctor’s instructions. Typically, it’s applied 2 to 4 times daily or as directed by your healthcare provider.
  • Avoid Contact with Eyes, Nose, and Mouth: Be careful to avoid getting Fluotrex cream into your eyes, nose, or mouth. If accidental contact occurs, rinse thoroughly with water.
  • Do Not Bandage or Cover Treated Area: Unless directed by your doctor, do not bandage or cover the treated area with a dressing or bandage.
  • Do Not Use on Broken or Infected Skin: Do not apply Fluotrex cream to broken or infected skin unless directed by your doctor.
  • Duration of Use: Do not use Fluotrex cream for longer than prescribed. Prolonged use may lead to adverse effects such as skin thinning.
  • Consult Doctor for Usage in Children: If using Fluotrex cream on a child, consult with a pediatrician for appropriate usage and dosage.

As always, follow your doctor’s instructions carefully when using Fluotrex or any other medication, and consult them if you have any questions or concerns.

Other uses for this medicine

Fluocinolone topical, such as Fluotrex, may have other uses beyond those explicitly prescribed by your doctor. However, any alternative use should only be undertaken under the guidance of a healthcare professional. Off-label uses may include certain types of dermatitis, pruritus (itching), and other inflammatory skin conditions.

What special precautions should I follow?

When using Fluotrex, it’s essential to take special precautions to ensure safe and effective use. Here are some key precautions to keep in mind:

  • Allergies: Inform your doctor if you have any allergies to Fluotrex or any other medications. Also, disclose any past allergic reactions to corticosteroids or other substances.
  • Medical History: Provide your healthcare provider with a comprehensive medical history, including any previous skin conditions, infections, or other health issues.
  • Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the potential risks and benefits of using Fluotrex with your doctor. It’s important to weigh the potential benefits against the risks, especially during pregnancy.
  • Children: Use caution when applying Fluotrex to children. Pediatric patients may be more susceptible to adverse effects, such as skin thinning, with prolonged use. Follow your doctor’s recommendations for pediatric use closely.
  • Avoid Contact with Eyes, Nose, and Mouth: Be careful to avoid getting Fluotrex into your eyes, nose, or mouth. If accidental contact occurs, rinse thoroughly with water.
  • Skin Integrity: Do not apply Fluotrex to broken, irritated, or infected skin unless directed by your doctor. Using corticosteroids on damaged skin can increase the risk of systemic absorption and adverse effects.
  • Interactions: Inform your doctor about all the medications, supplements, and herbal products you are currently taking, as they may interact with Fluotrex.
  • Systemic Absorption: Prolonged use of Fluotrex, especially over large areas of the body or under occlusive dressings, can lead to systemic absorption of the medication. This may increase the risk of systemic side effects, such as adrenal suppression.
  • Gradual Discontinuation: Abruptly stopping the use of Fluotrex after prolonged use may cause a rebound effect, where the symptoms worsen. Follow your doctor’s instructions for tapering off the medication gradually if necessary.

Always use Fluotrex exactly as prescribed by your doctor and follow all instructions provided on the medication label. If you experience any adverse effects or have concerns about its use, consult your healthcare provider promptly.

What special dietary instructions should I follow?

As for special dietary instructions, there are typically no specific dietary restrictions associated with the use of Fluotrex. However, maintaining a healthy and balanced diet can support overall skin health and may complement the effectiveness of the treatment.

What should I do if I forget a dose?

If you forget to apply a dose of Fluotrex, apply it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not apply extra medication to make up for the missed dose, as this can increase the risk of side effects. If you have any concerns or questions about missed doses, consult your healthcare provider for guidance.

What side effects can this medication cause?

Fluotrex, like other corticosteroids, can cause side effects, although not everyone will experience them. Common side effects may include:

  • Skin Irritation: This can manifest as burning, itching, redness, or stinging at the application site.
  • Skin Thinning: Prolonged use or excessive application of Fluotrex can lead to skin thinning (atrophy), making the skin more fragile and prone to bruising.
  • Skin Discoloration: Long-term use of Fluotrex may cause changes in skin pigmentation, such as lightening or darkening of the skin.
  • Acne: Some individuals may experience acne or worsening of existing acne while using Fluotrex.
  • Excessive Hair Growth: Rarely, Fluotrex may cause excessive hair growth (hypertrichosis) at the application site.
  • Stretch Marks: Prolonged use of high-potency corticosteroids like Fluotrex may increase the risk of developing stretch marks (striae) on the skin.
  • Allergic Reactions: In some cases, individuals may experience allergic reactions to Fluotrex, characterized by rash, hives, itching, swelling, or difficulty breathing. Seek immediate medical attention if you experience any signs of an allergic reaction.
  • Adrenal Suppression: Prolonged use of Fluotrex over large areas of the body or under occlusive dressings may lead to systemic absorption of the medication, potentially causing adrenal suppression, especially in children or with long-term use.
  • Glaucoma or Cataracts: If Fluotrex comes into contact with the eyes, it may increase the risk of developing glaucoma or cataracts. Avoid contact with the eyes and seek medical attention if accidental exposure occurs.
  • Infection: Prolonged use of corticosteroids can suppress the immune system, increasing the risk of secondary bacterial, fungal, or viral infections of the skin.

It’s important to note that these are not all the possible side effects of Fluotrex. Some individuals may experience other side effects not listed here. If you experience any concerning symptoms or side effects while using Fluotrex, consult your healthcare provider for further evaluation and guidance.

What should I know about storage and disposal of this medication?

Storage and Disposal of Fluotrex:


  • Store fluocinolone topical (such as Fluotrex) at room temperature away from moisture and heat.
  • Keep the medication out of reach of children and pets to prevent accidental ingestion.


  • Dispose of unused or expired Fluotrex properly according to local guidelines or as directed by your pharmacist.
  • Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Proper disposal helps prevent environmental contamination.

In case of emergency/overdose

  • In case of accidental ingestion of Fluotrex or if you suspect an overdose, contact your local poison control center (in the United States, you can reach Poison Help at 1-800-222-1222) or seek emergency medical attention immediately.
  • If someone has applied too much Fluotrex or if it has been ingested, symptoms of overdose may include excessive skin irritation, systemic effects such as adrenal suppression, or other adverse reactions.

What other information should I know?

  • Do not share Fluotrex with others, even if they have similar symptoms. This medication is prescribed for your specific condition and should not be used by others without medical advice.
  • Follow your doctor’s instructions closely regarding the duration and frequency of use of Fluotrex. Prolonged or excessive use can increase the risk of side effects.
  • Inform all healthcare providers involved in your care (such as doctors, dentists, and pharmacists) about all the medications you are using, including Fluotrex, to prevent potential drug interactions.
  • Avoid exposure to sunlight or artificial UV rays (such as tanning beds) while using Fluotrex, as it may increase the risk of sunburn or skin sensitivity.
  • If your condition does not improve or worsens while using Fluotrex, consult your healthcare provider for further evaluation and treatment.

Always follow your doctor’s advice and read the patient information leaflet provided with the medication for additional guidance and precautions specific to your treatment with Fluotrex.

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