PrescriptionGiant is a FREE prescription savings program that can save you up to 75% on your prescriptions with or without insurance!

Fluoroplex Cream (Generic Fluorouracil Topical)

Actual product appearance may differ slightly.

Click the CARD below to print or take a screenshot on your mobile phone or tablet. There is no need to download another app!

If you would like to personalize your card enter your full name in the member name field below the card at this link and click the Update button.


Why is this medication prescribed?

Fluoroplex Cream is a prescription medication primarily used for the treatment of actinic or solar keratoses, a condition characterized by rough, scaly patches on the skin caused by prolonged exposure to the sun. It contains the active ingredient fluorouracil, which belongs to a class of medications known as antimetabolites. Fluorouracil works by interfering with the growth of abnormal cells on the skin’s surface.

How should this medicine be used?

Here’s how Fluoroplex Cream should be used:

  • Follow the Instructions of Your Healthcare Provider: Use Fluoroplex Cream exactly as prescribed by your doctor. Do not use more or less of it or use it more often than prescribed.
  • Clean and Dry the Affected Area: Before applying Fluoroplex Cream, wash the affected area with mild soap and water and pat it dry gently.
  • Apply a Thin Layer: Apply a thin layer of Fluoroplex Cream to the affected area(s) using clean fingertips. Avoid getting the cream in your eyes, nose, mouth, or other mucous membranes. If contact occurs, rinse thoroughly with water.
  • Wash Your Hands After Application: After applying the cream, wash your hands thoroughly to avoid accidental contact with other areas of your skin or mucous membranes.
  • Avoid Bandages or Occlusive Dressings: Unless specifically instructed by your doctor, do not cover the treated area with bandages or occlusive dressings as this may increase absorption of the medication.
  • Use Regularly as Directed: Use Fluoroplex Cream as directed by your healthcare provider. Treatment duration can vary, but typically the cream is applied once or twice daily for several weeks. Your doctor will determine the appropriate duration of treatment based on your individual condition.
  • Expect Skin Reactions: It is common to experience skin reactions such as redness, peeling, itching, and burning at the application site. These reactions are usually temporary and indicate that the medication is working. However, if the irritation becomes severe or persistent, consult your doctor.
  • Avoid Sun Exposure: During treatment with Fluoroplex Cream, protect the treated area(s) from sun exposure by wearing protective clothing and using sunscreen.
  • Continue Treatment as Directed: Even if the affected area appears to improve, continue using Fluoroplex Cream for the full prescribed duration unless otherwise directed by your doctor. Stopping treatment prematurely may result in incomplete resolution of the condition.
  • Regular Follow-Up: Your doctor may schedule regular follow-up appointments to monitor your progress and adjust treatment as needed.

It’s crucial to adhere to your doctor’s instructions and report any concerns or side effects experienced during treatment.

Other uses for this medicine

Fluoroplex Cream, containing fluorouracil, is primarily prescribed for the treatment of actinic or solar keratoses, as mentioned earlier. However, it may also have other off-label uses, as determined by your healthcare provider. Some of these off-label uses may include the treatment of superficial basal cell carcinoma, Bowen’s disease (squamous cell carcinoma in situ), and genital warts caused by human papillomavirus (HPV).

What special precautions should I follow?

As with any medication, it’s essential to take special precautions when using Fluoroplex Cream. Here are some key considerations:

  • Allergic Reactions: Before using Fluoroplex Cream, inform your doctor if you have a history of allergies to fluorouracil or any other medications. Allergic reactions to Fluoroplex Cream can manifest as itching, swelling, rash, or difficulty breathing. If you experience any signs of an allergic reaction, discontinue use and seek medical attention immediately.
  • Avoid Contact with Eyes, Nose, and Mouth: Fluoroplex Cream is for external use only. Avoid contact with eyes, nose, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water.
  • Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using Fluoroplex Cream with your doctor. It is essential to weigh the potential risks to the fetus or infant against the benefits of treatment.
  • Skin Sensitivity: Fluoroplex Cream may cause skin irritation, including redness, peeling, itching, and burning at the application site. If these symptoms become severe or persistent, consult your doctor.
  • Sun Protection: During treatment with Fluoroplex Cream, protect the treated area(s) from sun exposure by wearing protective clothing, using sunscreen, and avoiding prolonged sun exposure. Fluorouracil can increase sensitivity to sunlight, leading to sunburn and other skin damage.
  • Avoid Bandages or Occlusive Dressings: Unless specifically instructed by your doctor, do not cover the treated area with bandages or occlusive dressings. This can increase the absorption of the medication and may lead to adverse effects.
  • Avoid Cosmetic Products: Avoid applying cosmetics, lotions, or other skincare products to the treated area(s) unless directed by your doctor.
  • Medical History: Inform your doctor about your medical history, especially if you have a history of skin conditions, immune system disorders, or if you are undergoing treatment for any other medical conditions.
  • Other Medications: Inform your doctor about all prescription, over-the-counter, and herbal medications you are taking, as well as any dietary supplements, to avoid potential interactions with Fluoroplex Cream.
  • Regular Follow-Up: Attend all scheduled follow-up appointments with your doctor to monitor your progress and adjust treatment as needed.

By following these precautions and your doctor’s instructions, you can use Fluoroplex Cream safely and effectively for the treatment of your skin condition.

What special dietary instructions should I follow?

Regarding special dietary instructions for Fluoroplex Cream, there are typically no specific dietary restrictions associated with its use. However, it’s always a good idea to maintain a balanced diet and stay hydrated during treatment. If you have any concerns or questions about dietary considerations, it’s best to discuss them with your healthcare provider.

What should I do if I forget a dose?

If you forget to apply a dose of Fluoroplex Cream, apply it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not apply extra cream to make up for a missed dose. Using too much Fluoroplex Cream can increase the risk of side effects. If you have any concerns or questions about missed doses, consult your healthcare provider for guidance.

What side effects can this medication cause?

Fluoroplex Cream, containing fluorouracil as its active ingredient, may cause side effects, which can vary in severity and frequency among individuals. Some common side effects of Fluoroplex Cream include:

  • Skin Irritation: Redness, swelling, itching, and burning at the application site are common side effects of Fluoroplex Cream. These reactions usually occur shortly after applying the cream and may improve with continued use.
  • Skin Dryness and Peeling: The treated area may become dry and begin to peel as a result of using Fluoroplex Cream. This is a normal reaction to the medication and indicates that it is working to eliminate abnormal skin cells.
  • Pain or Discomfort: Some individuals may experience mild pain or discomfort at the application site, particularly during the initial stages of treatment. This usually subsides as the skin adjusts to the medication.
  • Photosensitivity: Fluorouracil can increase the skin’s sensitivity to sunlight, leading to an increased risk of sunburn and other sun-related skin damage. It’s important to protect the treated area(s) from sun exposure by wearing protective clothing and using sunscreen during treatment.
  • Blistering or Crusting: In some cases, Fluoroplex Cream may cause blistering, crusting, or oozing at the application site. These reactions are less common but may occur, particularly if the cream is applied to sensitive areas of the skin or in higher concentrations.
  • Skin Changes: Long-term use of Fluoroplex Cream may cause changes in skin pigmentation, including darkening or lightening of the treated area(s). These changes are usually temporary and resolve once treatment is completed.
  • Allergic Reactions: Although rare, some individuals may experience allergic reactions to Fluoroplex Cream, including rash, hives, itching, swelling, or difficulty breathing. If you experience any signs of an allergic reaction, discontinue use and seek medical attention immediately.
  • Eye Irritation: Avoid getting Fluoroplex Cream in your eyes, as it can cause irritation and discomfort. If accidental contact occurs, rinse thoroughly with water.

It’s important to note that not everyone will experience these side effects, and some individuals may experience side effects not listed here. If you have concerns about side effects or experience any unusual symptoms while using Fluoroplex Cream, consult your healthcare provider for further evaluation and guidance.

What should I know about storage and disposal of this medication?

Storage and disposal of Fluoroplex Cream:

  • Storage of Fluoroplex Cream:
    • Store Fluoroplex Cream at room temperature, away from heat, moisture, and direct light.
    • Keep the medication out of reach of children and pets.
    • Do not freeze Fluoroplex Cream.
    • Ensure the tube is tightly closed when not in use.
    • Do not store Fluoroplex Cream in the bathroom, as moisture can degrade the medication.
  • Disposal of Fluoroplex Cream:
    • Dispose of Fluoroplex Cream properly according to local regulations or guidelines.
    • Do not flush Fluoroplex Cream down the toilet or drain unless instructed to do so.
    • Consult your pharmacist or healthcare provider for instructions on how to safely dispose of unused or expired Fluoroplex Cream.

In case of emergency/overdose

In case of emergency or overdose of Fluoroplex Cream:

  • In case of accidental ingestion or overdose of Fluoroplex Cream, contact your local poison control center or emergency room immediately.
  • If possible, bring the medication container or label to the healthcare provider to assist with treatment.

What other information should I know?

  • Keep all appointments with your doctor for regular follow-up and monitoring during treatment with Fluoroplex Cream.
  • Inform any healthcare provider involved in your care that you are using Fluoroplex Cream.
  • Do not share Fluoroplex Cream with others, even if they have similar symptoms.
  • Follow your doctor’s instructions carefully regarding the duration and frequency of Fluoroplex Cream application.
  • Report any new or worsening symptoms to your doctor promptly, including severe skin irritation, blistering, or signs of infection at the application site.
  • It may take several weeks of treatment before noticeable improvement occurs in the treated skin areas. Be patient and continue using Fluoroplex Cream as directed.
  • Avoid using other topical medications or treatments on the same area(s) of skin without consulting your doctor first.

By following these guidelines and staying informed about the proper use, storage, disposal, and potential risks associated with Fluoroplex Cream, you can use the medication safely and effectively for the treatment of your skin condition.

Copyright © 2023 PrescriptionGiant.com