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Florone (Generic Diflorasone Topical)

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Why is this medication prescribed?

Diflorasone is used to treat a variety of skin conditions, including eczema and psoriasis, which can cause the skin to become dry, itchy, and occasionally develop red, scaly rashes. These conditions can all cause itchiness, redness, dryness, crusting, scaling, inflammation, and discomfort. Diflorasone belongs to the corticosteroid drug class. It reduces swelling, redness, and itching by causing natural chemicals in the skin to become active.

How should this medicine be used?

Diflorasone is available as a skin-applying cream and ointment. The affected area is typically treated one to three times each day. Apply diflorasone daily at roughly the same time to help you remember to do so. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Utilize diflorasone precisely as advised. Use it only as directed by your doctor, neither more nor less often.

Apply a small amount of cream or ointment to the affected area of skin to create a thin film before using diflorasone topical.

Only the skin should be used to apply this medication. Do not swallow diflorasone topical and avoid getting it in your eyes or mouth.Unless specifically instructed by your doctor, avoid using it on the face, in genital and rectal areas, as well as in skin folds and armpits.

Avoid using plastic or tight-fitting diapers while applying diflorasone to a child’s diaper area. Such use could exacerbate negative effects.

Without first consulting your doctor, avoid using any other skin creams or preparations on the treated region.

Only bandage or wrap the treated area if your doctor instructs you to. Such use could exacerbate negative effects.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before using diflorasone,

  • If you have an allergy to diflorasone, any other drugs, or any of the ingredients in diflorasone topical treatments, inform your doctor and pharmacist right away. Request a list of the ingredients from your pharmacist.
  • Inform your physician and pharmacist about all prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are taking.
  • Inform your doctor if you have any skin issues, infections, diabetes, or Cushing’s syndrome, a disorder brought on by excessive hormones (corticosteroids).
  • If you are breastfeeding a child or intend to become pregnant, let your doctor know. Call your doctor right away if you find out you’re pregnant while taking diflorasone.
  • Inform the surgeon or dentist that you are using betamethasone topical if you are having surgery, including dental surgery.

What should I do if I forget a dose?

As soon as you recall, take the missed dose. Skip the missed dose and carry on with your regular dosing plan, nevertheless, if it is almost time for the subsequent dose. To make up for a missing dose, avoid applying a second one.

What side effects can this medication cause?

Diflorasone could have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Skin that is burning, itchy, irritated, red, or dry or cracked
  • Acne
  • Rash
  • Higher hair growth
  • Alteration in skin tone
  • Skin that is glossy or bruised
  • Rash or small red pimples around the mouth
  • Small skin bumps that are white or red

Some adverse effects can be very harmful. Call your doctor right away if you have any of the following symptoms:

  • Redness, swelling, pustules, or other symptoms of a skin infection where you used the diflorasone cream.
  • Alterations in the body’s fat distribution
  • Unexpected weight gain
  • Strange fatigue
  • Muscular tremor
  • Moodiness and depression

Children who use topical diflorasone may be more likely to experience negative side effects, such as reduced growth and delayed weight gain. Discuss the dangers of giving your child medication topically with your doctor.

There may be more negative effects with difflorasone. If you experience any strange issues while taking this drug, call your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online at or by phone at 1-800-332-1088 if you have a serious side event.

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Keep it at room temperature and out of the bathroom and other places with excessive heat and moisture.

To make sure that pets, kids, and other people cannot take leftover pharmaceuticals, they should be disposed of in a specific manner. You shouldn’t flush this medication down the toilet, though. The best option to get rid of your medication is instead through a medication take-back program. To find out about take-back initiatives in your neighborhood, speak with your pharmacist or get in touch with your city’s waste/recycling department. If you do not have access to a take-back program, you can find more information at the FDA’s Safe Disposal of Medicines website (

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

In case of emergency/overdose

Dial 1-800-222-1222 to reach your local poison control center if someone consumes diflorasone topical. Dial 911 to reach the nearest emergency services if the sufferer has collapsed or has stopped breathing.

What other information should I know?

Keep all of your appointments with your physician and the lab. To determine how well your body is responding to diflorasone, your doctor may request specific lab tests.

Do not share your medication with anybody else. Use just for the skin problem for which it was given. Do not use for any other skin conditions. Any queries you may have regarding medication refills should be directed to your pharmacist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Florone®
  • Psorcon®
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