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Flo-Pred (Generic Prednisolone)

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Why is this medication prescribed?

Prednisolone is a corticosteroid medication that is prescribed for a variety of conditions due to its anti-inflammatory and immunosuppressive properties. Some common reasons why Prednisolone may be prescribed include:

  • Inflammatory conditions: Prednisolone is often prescribed to reduce inflammation associated with conditions such as arthritis, asthma, inflammatory bowel disease (such as Crohn’s disease or ulcerative colitis), and dermatitis.
  • Allergic reactions: It can be used to alleviate symptoms of severe allergic reactions, such as those involving the skin, eyes, respiratory system, or anaphylaxis.
  • Autoimmune diseases: Prednisolone may be prescribed to manage symptoms of autoimmune diseases like lupus, rheumatoid arthritis, or multiple sclerosis, where the immune system mistakenly attacks healthy tissues.
  • Certain cancers: Prednisolone can be a part of chemotherapy regimens for certain types of cancers to reduce inflammation and suppress the immune response.
  • Organ transplants: Prednisolone may be used as part of immunosuppressive therapy to prevent rejection of transplanted organs.

How should this medicine be used?

Here are some general guidelines for its use:

  • Dosage: The dosage of Prednisolone will vary depending on the condition being treated, its severity, and individual patient factors. It’s crucial to take the prescribed dosage as directed by your healthcare provider.
  • Administration: Prednisolone is typically taken orally in the form of tablets or liquid. It may also be administered via injection in certain situations, such as in a hospital setting.
  • Timing: Prednisolone is often taken once daily, usually in the morning, with or without food. However, specific instructions may vary, so follow your doctor’s recommendations carefully.
  • Duration: Prednisolone treatment is usually short-term for acute conditions, but it may be long-term for chronic conditions. It’s essential not to stop taking Prednisolone suddenly without consulting your doctor, as this can lead to withdrawal symptoms.
  • Monitoring: Regular follow-up appointments with your healthcare provider are essential to monitor your response to Prednisolone treatment and to adjust the dosage or treatment plan if necessary. Prednisolone can have various side effects, so your doctor will want to ensure that the benefits outweigh the risks.
  • Side effects: Be aware of potential side effects of Prednisolone, which can include weight gain, increased appetite, insomnia, mood changes, high blood pressure, and increased susceptibility to infections. If you experience any concerning symptoms, notify your doctor promptly.

Always communicate openly with your healthcare provider about any concerns or questions you have regarding your Prednisolone treatment.

Other uses for this medicine

Aside from its primary use as an anti-inflammatory and immunosuppressant, prednisolone may also be prescribed for:

  • Allergic reactions
  • Asthma
  • Rheumatic disorders
  • Dermatological conditions like eczema and psoriasis
  • Certain types of cancer in combination with other medications

What special precautions should I follow?

As for special precautions when using Prednisolone, here are some important points to consider:

  • Follow doctor’s instructions: Always take Prednisolone exactly as prescribed by your healthcare provider. Do not adjust the dosage or stop taking it without consulting your doctor first.
  • Gradual withdrawal: Long-term use of Prednisolone should be tapered off gradually under the guidance of a healthcare professional to avoid withdrawal symptoms and potential adrenal insufficiency.
  • Monitor for side effects: Be vigilant for any side effects of Prednisolone, such as increased blood sugar levels, mood changes, fluid retention, weight gain, or increased susceptibility to infections. Report any concerning symptoms to your doctor promptly.
  • Avoid sudden discontinuation: Abruptly stopping Prednisolone can lead to withdrawal symptoms, including fatigue, muscle weakness, joint pain, and fever. Your doctor will provide guidance on how to taper off the medication safely if necessary.
  • Interactions with other medications: Inform your doctor about all medications, supplements, or herbal remedies you are taking, as Prednisolone may interact with certain drugs, including blood thinners, insulin or diabetes medications, and vaccines.
  • Medical conditions: Inform your doctor if you have any medical conditions, such as diabetes, hypertension, osteoporosis, or gastrointestinal disorders, as Prednisolone may exacerbate these conditions or require special monitoring.
  • Pregnancy and breastfeeding: Prednisolone should be used with caution during pregnancy and breastfeeding, as it may pose risks to the fetus or infant. Discuss the risks and benefits with your healthcare provider before using Prednisolone during pregnancy or while breastfeeding.

By following these precautions and guidelines, you can use Prednisolone safely and effectively under the supervision of your healthcare provider. Always communicate openly with your doctor about any concerns or questions you may have regarding your medication regimen.

What special dietary instructions should I follow?

  • It’s generally recommended to take Prednisolone with food or milk to help prevent stomach upset.
  • Avoid excessive consumption of alcohol, as it can increase the risk of stomach irritation and other side effects associated with Prednisolone.
  • Maintain a balanced diet rich in fruits, vegetables, and whole grains to minimize potential side effects such as weight gain and bone loss.

What should I do if I forget a dose?

  • If you forget to take a dose of Prednisolone, take it as soon as you remember, unless it’s almost time for your next scheduled dose.
  • If it’s close to your next dose, skip the missed dose and resume your regular dosing schedule.
  • Do not double the dose to make up for the missed one, as this can increase the risk of side effects.

What side effects can this medication cause?

Prednisolone, like other corticosteroid medications, can cause a range of side effects, which may vary depending on factors such as dosage, duration of use, and individual susceptibility. Some common side effects of Prednisolone include:

  • Increased appetite and weight gain: Corticosteroids like Prednisolone can stimulate appetite and lead to weight gain, particularly with long-term use.
  • Fluid retention: Prednisolone can cause sodium and water retention, leading to bloating, swelling (edema), and increased blood pressure.
  • Mood changes: Some individuals may experience mood swings, irritability, anxiety, or even depression while taking Prednisolone.
  • Insomnia: Difficulty falling asleep or staying asleep may occur as a side effect of Prednisolone.
  • Gastrointestinal symptoms: Prednisolone can irritate the digestive system, leading to symptoms such as indigestion, nausea, vomiting, or abdominal discomfort. Long-term use may increase the risk of gastric ulcers or gastrointestinal bleeding.
  • Increased risk of infections: Corticosteroids suppress the immune system, making individuals more susceptible to infections. This can include viral, bacterial, fungal, or parasitic infections.
  • Delayed wound healing: Prednisolone can impair the body’s ability to heal wounds, leading to slower recovery times.
  • Osteoporosis: Long-term use of Prednisolone can lead to bone loss (osteoporosis), increasing the risk of fractures.
  • Muscle weakness: Prolonged use of Prednisolone can lead to muscle weakness and may increase the risk of tendon rupture.
  • Glaucoma and cataracts: Prednisolone eye drops or prolonged systemic use can increase the risk of developing glaucoma or cataracts.
  • Adrenal suppression: Long-term use of Prednisolone can suppress the function of the adrenal glands, leading to adrenal insufficiency when the medication is discontinued suddenly.
  • Hyperglycemia: Prednisolone can increase blood sugar levels, particularly in individuals with diabetes or those predisposed to diabetes.
  • Skin changes: Some individuals may experience thinning of the skin, easy bruising, or increased susceptibility to skin infections while taking Prednisolone.

It’s essential to monitor for these side effects while taking Prednisolone and to report any concerning symptoms to your healthcare provider. In some cases, adjustments to the dosage or treatment plan may be necessary to manage side effects effectively. Additionally, long-term use of Prednisolone should be done under the supervision of a healthcare professional to minimize the risk of adverse effects.

What should I know about storage and disposal of this medication?

Storage and disposal of Prednisolone:


  • Follow instructions: Store Prednisolone tablets, liquid, or eye drops at room temperature away from moisture and heat. Follow any specific storage instructions provided by your pharmacist or healthcare provider.
  • Keep out of reach of children: Store Prednisolone in a location where it is inaccessible to children and pets to prevent accidental ingestion.
  • Avoid extreme temperatures: Do not freeze Prednisolone liquid. Protect it from direct sunlight, moisture, and high temperatures.
  • Check expiration date: Check the expiration date on the medication label, and do not use Prednisolone if it has expired. Dispose of expired medication properly.


  • Follow local guidelines: Dispose of unused or expired Prednisolone tablets, liquid, or eye drops according to local guidelines or regulations. Do not flush them down the toilet unless instructed to do so.
  • Take-back programs: Some pharmacies or healthcare facilities may offer medication take-back programs for safe disposal of unused or expired medications.
  • Dispose of properly: If a take-back program is not available, mix Prednisolone tablets with an undesirable substance (e.g., dirt, cat litter) in a sealed plastic bag before throwing it in the trash. Dispose of liquid medications by mixing them with an absorbent material (e.g., coffee grounds) in a sealed container before disposal.

In case of emergency/overdose

In case of emergency or overdose of Prednisolone:

  • Seek medical help: In case of an overdose or emergency, call your local emergency services or poison control center immediately. Provide them with information about the amount of Prednisolone ingested and any symptoms experienced.
  • Symptom management: If someone has overdosed on Prednisolone, supportive care may be provided to manage symptoms such as nausea, vomiting, high blood pressure, or electrolyte disturbances.

What other information should I know?

  • Regular monitoring: Regularly monitor your response to Prednisolone treatment and attend follow-up appointments with your healthcare provider as scheduled. Your doctor may perform blood tests or other assessments to monitor for side effects or treatment efficacy.
  • Medication interactions: Inform your healthcare provider about all medications, supplements, or herbal remedies you are taking, as Prednisolone may interact with certain drugs. Avoid starting or stopping any medications without consulting your doctor.
  • Medical identification: Consider wearing a medical identification bracelet or necklace indicating that you are taking Prednisolone, especially if you have adrenal insufficiency or are at risk of adrenal crisis.
  • Avoid alcohol and smoking: Limit alcohol consumption and avoid smoking while taking Prednisolone, as these substances can increase the risk of certain side effects and may interfere with the effectiveness of the medication.
  • Education and support: Educate yourself about Prednisolone, its potential side effects, and how to manage them. Seek support from healthcare professionals, support groups, or counseling services if needed to cope with the challenges of managing a chronic condition requiring Prednisolone treatment.

By following these guidelines for storage, disposal, emergency response, and additional information, you can ensure safe and effective use of Prednisolone under the guidance of your healthcare provider. Always consult your doctor or pharmacist if you have any questions or concerns about your medication regimen.

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