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Flagyl I.V. RTU (Generic Metronidazole Injection)

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Injections of metronidazole can lead to cancer in lab animals. Discuss the advantages and disadvantages of using this medicine with your doctor.

Why is this medication prescribed?

Specific bacterial infections of the skin, blood, bones, joints, gynecology, abdomen (stomach area), and skin are treated with metronidazole injection. Additionally, it is used to treat pneumonia as well as other respiratory infections such endocarditis, meningitis, and infections of the membranes around the brain and spinal cord. When taken before to, during, and following colorectal surgery, metronidazole injection also serves to prevent infection. A group of drugs known as antibacterials includes metronidazole injection. Infection-causing bacteria and protozoa are killed by it.

Colds, the flu, or other viral diseases cannot be treated with antibiotics, such as metronidazole injection. Antibiotic use that is not necessary raises the likelihood of developing a later infection that is resistant to antibiotic treatment.respiratory tract illnesses, such as bronchitis and pneumonia.

How should this medicine be used?

The solution form of metronidazole injection is infused intravenously (slowly injected into a vein). Every six hours, it is typically infused over the course of 30 to an hour. The type of infection being treated determines the course of the treatment. The duration of metronidazole injectable use will be specified by your doctor.

You can use metronidazole injection at home or get it administered in a hospital. Your doctor will demonstrate how to administer the drug to you if you will be administering metronidazole injection at home. Make sure you comprehend these instructions, and if you have any issues, consult your healthcare professional.

During the first several days of metronidazole injectable therapy, you should start to feel better. Call your doctor if your symptoms do not disappear or worsen.

Even if you feel better, keep using the metronidazole injection until the prescription is finished. Your illness could not be entirely treated if you stop taking metronidazole injection too soon or if you skip doses, and the bacteria might develop an antibiotic resistance.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before using metronidazole injection,

  • If you have an allergy to metronidazole, any other drugs, or any of the ingredients in metronidazole injection, let your doctor and pharmacist know right away. Request a list of the components from your pharmacist.
  • If you have taken or are now taking disulfiram (Antabuse), let your doctor know. If you are now taking this drug or have recently taken it within the past two weeks, your doctor generally won’t advise you to use metronidazole injection.
  • Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Incorporate any of the following: Warfarin (Coumadin, Jantoven), busulfan (Buselfex, Myleran), cimetidine (Tagamet), corticosteroids, lithium (Lithobid), phenobarbital, and phenytoin (Dilantin, Phenytek) are anticoagulants (sometimes known as “blood thinners”). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects. Tell your doctor about all of the medicines you are taking, even any not on this list, since many other drugs may also interact with metronidazole injection.
  • A yeast infection, edema (fluid retention and swelling; excessive fluid held in body tissues), Crohn’s disease (a condition in which the body attacks the lining of the digestive tract, causing pain, diarrhea, weight loss, and fever), blood, kidney, or liver disease are all things you should mention to your doctor.
  • Remember to refrain from consuming alcohol or using items containing alcohol or propylene glycol while receiving metronidazole injection and for at least three days following the end of treatment. When consumed while receiving metronidazole injectable treatment, alcohol and propylene glycol may result in nausea, vomiting, stomach cramps, headache, perspiration, and flushing (redness of the face).
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor if you get pregnant while taking metronidazole injectable.

What special dietary instructions should I follow?

Keep eating normally unless your doctor instructs you otherwise.

What side effects can this medication cause?

The injection of metronidazole may have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Nausea
  • Vomiting
  • Reduced appetite
  • Stomach cramps and agony
  • Diarrhea
  • Constipation
  • Headache
  • Irritability
  • Depression
  • Weakness
  • Having trouble falling or staying asleep
  • Dry mouth, a noxious metallic taste,
  • Tongue that is hairy; mouth or tongue inflammation
  • Inflammation, discomfort, or pain at the injection site

Some negative effects may be quite detrimental. If you have any of the following symptoms, call your doctor immediately and stop taking metronidazole injection:

  • Rash
  • Itching
  • Hives
  • Blistering, peeling, or loss of the localized skin
  • Flushing
  • Seizures
  • Tingling, burning, or numbness in your feet or hands
  • Fever, light sensitivity in the eyes, and stiff neck
  • Having trouble speaking
  • Difficulty coordinating
  • Confusion
  • Fainting
  • Dizziness

Other negative effects of metronidazole injection are possible. If you experience any strange issues while taking this drug, call your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online at or by phone at 1-800-332-1088 if you have a serious side event.

What other information should I know?

Inform the lab staff and your doctor that you are taking metronidazole injection prior to any laboratory test.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Flagyl® I.V.
  • Flagyl® I.V. RTU®
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