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Fiormor (Generic Aspirin, Butalbital, and Caffeine)

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Why is this medication prescribed?

Aspirin, Butalbital, and Caffeine are commonly prescribed together in a medication known as a combination analgesic for the treatment of tension headaches and migraines. Each component serves a specific purpose:

  • Aspirin: Aspirin is a nonsteroidal anti-inflammatory drug (NSAID) that helps reduce inflammation, pain, and fever. It works by inhibiting the production of certain chemicals in the body that cause pain and inflammation.
  • Butalbital: Butalbital is a barbiturate that acts as a central nervous system depressant. It helps to relax muscle contractions in the head and neck, thereby reducing the intensity of tension headaches and migraines.
  • Caffeine: Caffeine is a central nervous system stimulant that is added to enhance the effectiveness of the other ingredients. It can help increase the absorption of aspirin and provide additional relief by constricting blood vessels in the brain.

The combination of these three ingredients is believed to work synergistically to provide more effective pain relief than any of the components alone.

How should this medicine be used?

As for how to use Aspirin, Butalbital, and Caffeine:

  • Dosage: The dosage of this combination medication depends on the specific formulation and the severity of the headache. It’s essential to follow the doctor’s instructions or the dosage information provided on the medication label.
  • Frequency: Typically, this medication is taken as needed for pain relief. However, it’s important not to exceed the recommended dosage or frequency, as excessive use can lead to tolerance, dependence, and potential overdose.
  • Administration: The medication is usually taken orally with a full glass of water. It can be taken with or without food, but taking it with food may help reduce stomach upset.
  • Timing: It’s best to take the medication as soon as symptoms of a headache begin for the most effective relief. Waiting too long to take the medication may decrease its effectiveness.
  • Caution: It’s important to avoid alcohol while taking this medication, as alcohol can increase the risk of side effects such as dizziness, drowsiness, and liver damage.

It’s crucial to use this medication exactly as prescribed by a healthcare professional and to contact a doctor if the headaches persist or worsen despite treatment. Additionally, long-term or excessive use of this medication should be avoided due to the risk of medication overuse headaches and other potential adverse effects.

Other uses for this medicine

Aside from tension headaches and migraines, the combination of Aspirin, Butalbital, and Caffeine may also be used for the treatment of other types of pain conditions, such as muscle pain, dental pain, menstrual cramps, and certain types of arthritis. However, it’s essential to note that this medication should only be used for these purposes under the guidance and prescription of a healthcare professional.

What special precautions should I follow?

Special precautions should be taken when using Aspirin, Butalbital, and Caffeine:

  • Allergies: Inform your doctor if you have any allergies to aspirin, butalbital, caffeine, or any other medications. This medication may contain inactive ingredients that can cause allergic reactions or other problems.
  • Medical History: Provide a detailed medical history to your doctor, especially if you have a history of certain medical conditions such as asthma, liver disease, kidney disease, stomach ulcers, bleeding disorders, substance abuse, or mental/mood disorders.
  • Pregnancy and Breastfeeding: It’s important to discuss the risks and benefits of using this medication during pregnancy or while breastfeeding with your healthcare provider. Aspirin may be harmful to the fetus, and butalbital may pass into breast milk and could have adverse effects on a nursing infant.
  • Interactions: Inform your doctor about all the medications you are currently taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. Certain medications may interact with Aspirin, Butalbital, and Caffeine, potentially increasing the risk of side effects or reducing the effectiveness of the medication.
  • Alcohol: Avoid consuming alcohol while taking this medication, as it can increase the risk of side effects such as dizziness, drowsiness, and liver damage.
  • Driving and Operating Machinery: This medication may cause drowsiness, dizziness, or impaired judgment. Avoid driving, operating machinery, or engaging in activities that require mental alertness until you know how this medication affects you.
  • Overuse: Do not exceed the recommended dosage or frequency of use of this medication. Overuse of combination analgesics containing butalbital can lead to tolerance, dependence, medication overuse headaches, and withdrawal symptoms when discontinued.
  • Storage: Store this medication at room temperature away from light and moisture. Keep it out of the reach of children and pets.

Always follow your doctor’s instructions and ask any questions you may have about the proper use and precautions of this medication. If you experience any concerning side effects or have any questions or concerns, contact your healthcare provider promptly.

What special dietary instructions should I follow?

There are no specific dietary instructions associated with Aspirin, Butalbital, and Caffeine. However, taking the medication with food may help reduce stomach upset.

What should I do if I forget a dose?

If you miss a dose of Aspirin, Butalbital, and Caffeine, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.

What side effects can this medication cause?

Aspirin, Butalbital, and Caffeine, like any medication, can cause side effects. Not everyone will experience these side effects, and their severity can vary. Common side effects of this combination medication may include:

  • Drowsiness
  • Dizziness
  • Nausea or vomiting
  • Upset stomach
  • Heartburn
  • Increased urination
  • Excitability or nervousness
  • Tremors
  • Difficulty sleeping (insomnia)
  • Rash or itching

More serious side effects are rare but may include:

  • Allergic reactions, such as rash, itching, swelling of the face, tongue, or throat, severe dizziness, or trouble breathing
  • Stomach bleeding or ulcers, which may cause abdominal pain, black or tarry stools, or vomiting blood
  • Liver problems, indicated by dark urine, persistent nausea or vomiting, stomach or abdominal pain, yellowing eyes or skin (jaundice)
  • Kidney problems, manifested by change in the amount of urine, swelling ankles/feet, persistent fatigue, or unusual/sudden weight gain
  • Mental/mood changes, such as confusion, hallucinations, depression, or unusual excitement

It’s important to contact your healthcare provider if you experience any of these side effects, especially if they persist or worsen over time. Additionally, if you experience any severe or concerning side effects, seek medical attention immediately.

This is not an exhaustive list of side effects. If you have any concerns about side effects or experience any unusual symptoms while taking Aspirin, Butalbital, and Caffeine, consult your healthcare provider for further evaluation and advice.

What should I know about storage and disposal of this medication?

Storage and disposal guidelines for Aspirin, Butalbital, and Caffeine:


  • Store the medication at room temperature away from moisture, heat, and light.
  • Keep it out of reach of children and pets.
  • Do not store in the bathroom or near the kitchen sink where it might get wet.
  • Check the expiration date and discard any expired medication.


  • Follow any specific disposal instructions provided by your healthcare provider or pharmacist.
  • Do not flush medications down the toilet unless instructed to do so.
  • Dispose of unused or expired medication properly according to local regulations. You can inquire with your pharmacist or local waste management authority for guidance on safe disposal methods.

In case of emergency/overdose

In case of emergency/overdose of Aspirin, Butalbital, and Caffeine:

  • If you suspect an overdose or experience severe symptoms such as trouble breathing, seizures, loss of consciousness, or severe dizziness, seek immediate medical attention by calling emergency services or going to the nearest emergency room.
  • Be prepared to provide information about the type and amount of medication ingested, as well as any other relevant medical history.

What other information should I know?

  • Keep track of your medication usage and do not exceed the recommended dosage or frequency.
  • Inform healthcare providers of all medications, supplements, and herbal products you are taking to avoid potential drug interactions.
  • Attend regular follow-up appointments with your doctor to monitor your response to the medication and discuss any concerns or side effects.
  • Avoid alcohol consumption while taking this medication, as it may increase the risk of side effects such as drowsiness or liver damage.
  • Do not share this medication with others, even if they have similar symptoms, as it may not be suitable for their condition and could cause harm.
  • If you have any questions or concerns about your medication, dosage, or side effects, consult your healthcare provider or pharmacist for guidance.
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