Feraheme (Generic Ferumoxytol Injection)
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When receiving the medication and afterward, ferumoxytol injection may result in severe or fatal side effects. Each time you have a ferumoxytol injection, as well as for at least 30 minutes afterward, your doctor will keep a close eye on you. Shortness of breath, wheezing, breathing difficulties, hoarseness, swelling of the face, throat, tongue, lips, or eyes, hives, rash, itching, fainting, lightheadedness, dizziness, or loss of consciousness are just a few of the symptoms you should mention to your doctor if you experience them during or after your injection. Your physician will stop your infusion right away and administer emergency medical care if you have a severe response.
Why is this medication prescribed?
Adults with chronic renal disease (damage to the kidneys that may develop over time and may eventually cause the kidneys to stop working) are treated for iron-deficiency anemia (a lower than normal amount of red blood cells due to too little iron). When oral iron preparations did not work or the patient could not take them, ferumoxytol injection is used to treat iron deficiency anemia. The drug ferumoxytol injection belongs to the group of drugs known as iron replacement therapies. By replenishing iron reserves, it enables the body to produce more red blood cells.
How should this medicine be used?
An intravenous (IV) injection of ferumoxytol is administered by a doctor or nurse in a doctor’s office or hospital outpatient clinic as a solution (liquid). Usually, it is injected slowly over a period of at least 15 minutes. Two doses of ferumoxytol injection are typically administered, each spaced 3 to 8 days apart. After you finish your treatment, your doctor might reorder this medication if your iron levels drop or stay low.
Other uses for this medicine
Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.
What special precautions should I follow?
Before receiving ferumoxytol injection,
- Inform your doctor and pharmacist right away if you have any allergies to ferumoxytol injection, other iron injections such iron dextran (Dexferrum, InFed, Proferdex), iron sucrose (Venofer), sodium ferric gluconate (Ferrlecit), other drugs, or any of the chemicals in ferumoxytol injection. For a list of the ingredients, ask your pharmacist.
- Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Make sure to mention orally taken iron supplements. Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
- Inform your doctor of any medical conditions you now have or have ever had.
- Inform your physician if you are nursing a baby, intend to get pregnant, or are already pregnant. Call your doctor if you get pregnant while having an injection of ferumoxytol.
What special dietary instructions should I follow?
Keep eating normally unless your doctor instructs you otherwise.
What should I do if I forget a dose?
Call your doctor as soon as you can if you are unable to make a scheduled ferumoxytol injection visit.
What side effects can this medication cause?
An injection of ferumoxytol might have negative effects. If any of these symptoms are severe or do not go away, let your doctor know right once:
- Stomach pain
- Hands, feet, ankles, or lower legs swelling
Some adverse effects can be very harmful. Get emergency medical care or call your doctor right away if you encounter any of the symptoms described below or in the IMPORTANT WARNINGS section:
- A chest ache
Other side effects from ferumoxytol injection could also occur. If you have any strange side effects while taking this medicine, call your doctor right away.
You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online at http://www.fda.gov/Safety/MedWatch or by phone at 1-800-332-1088 if you have a serious side event.
In case of emergency/overdose
Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at https://www.poisonhelp.org/help. Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.
What other information should I know?
Keep all of your appointments with your physician and the lab. To determine how well your body has responded to the ferumoxytol injection, your doctor will monitor your blood pressure and request a few lab tests.
Inform your doctor and the MRI staff that you are receiving ferumoxytol injection before beginning any magnetic resonance imaging (MRI; a medical test that utilizes strong magnets to create images of the inside of the body). Up to three months following your last dose of the drug, ferumoxytol injection may have an impact on your MRI results.
You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.