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Femstat 3 (Generic Butoconazole Vaginal Cream)

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Why is this medication prescribed?

Treatment for vaginal yeast infections with butoconazole is available.

Ask your doctor or pharmacist for more details if you’re interested in using this drug for any other conditions.

How should this medicine be used?

Butoconazole is available as a vaginal cream injection. It is often administered every night before bed. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Follow the butoconazole directions exactly. Use it only as directed by your doctor, neither more nor less often.

Read the directions on the vaginal cream before using it, then perform the following actions:

  1. To the level specified, pour cream into the unique applicator that is included.
  2. Spread your legs apart as you lay on your back with your knees up.
  3. In order to discharge the drug, insert the applicator high into your vagina (unless you are pregnant). Gently insert the applicator if you are expecting. Do not attempt to insert it any farther if you encounter resistance (hard to implant); instead, call your doctor.
  4. Withdraw and discard the applicator.
  5. Quickly wash your hands to stop the infection from spreading.

When you lay down to go to bed, you should administer the dose. If you only get up to wash your hands after using the medication, it will function best. If you want to prevent stains on your clothes, you might choose to wear a sanitary napkin. Tampons should not be used since they will absorb the medication. Unless your doctor instructs you to douche, avoid doing so.

Even if you feel better, continue taking butoconazole. Without consulting your doctor, do not stop taking butoconazole. During your period, continue taking this medication.

What special precautions should I follow?

Before using butoconazole,

  • If you have an allergy to butoconazole or any other medication, inform your doctor and pharmacist right away.
  • Inform your doctor and pharmacist about all prescription and over-the-counter medications you are taking, including any antibiotics and vitamins.
  • Inform your doctor if you suffer from or have ever suffered from diabetes, immune system issues, HIV infection, or acquired immunodeficiency syndrome (AIDS).
  • Inform your doctor if you are expecting, intend to get pregnant, or are nursing a baby. Call your doctor if you become pregnant while taking butoconazole.

What should I do if I forget a dose?

As soon as you recall, take the missed dose. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. Never take two doses to make up for one that was missed.

What side effects can this medication cause?

Side effects from butoconazole are possible. Call your doctor right away if you have any of the following symptoms:

  • Burning when applying lotion to the vagina
  • Irritation in the vagina when applying cream
  • Abdominal pain
  • Fever
  • Stench of discharge

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online at or by phone at 1-800-332-1088 if you have a serious side event.

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Keep it at room temperature and out of the bathroom and other places with excessive heat and moisture. Avoid freezing.

To make sure that pets, kids, and other people cannot take leftover pharmaceuticals, they should be disposed of in a specific manner. You shouldn’t flush this medication down the toilet, though. The best option to get rid of your medication is instead through a medication take-back program. To find out about take-back initiatives in your neighborhood, speak with your pharmacist or get in touch with your city’s waste/recycling department. If you do not have access to a take-back program, you can find more information at the FDA’s Safe Disposal of Medicines website (

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

What other information should I know?

Keep all of your doctor’s appointments. Only external use of butoconazole is permitted. Avoid getting cream in your mouth or eyes, and never try to swallow it.

Avoid having sexual relations. Use of latex goods like condoms or diaphragms should be avoided for 72 hours after using the cream since one of its ingredients may weaken them. Wear clean cotton underwear, not underwear made of nylon, rayon, or other synthetic materials, or underwear with cotton crotches.

Do not share your medication with anybody else. Any queries you may have regarding medication refills should be directed to your pharmacist. Call your doctor if, after finishing the butoconazole, you continue to experience signs of infection.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Femstat 3®
  • Gynazole-1®
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