WARNING

Feldene, also known by its generic name piroxicam, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, inflammation, and stiffness caused by conditions such as arthritis. While it can be effective for managing these symptoms, there are several risks associated with taking Feldene:

• Gastrointestinal Side Effects: NSAIDs like Feldene can irritate the lining of the stomach and increase the risk of developing ulcers or gastrointestinal bleeding. This risk is higher in older adults and those with a history of stomach ulcers or bleeding disorders.
• Cardiovascular Risks: Feldene and other NSAIDs have been associated with an increased risk of heart attack, stroke, and other cardiovascular events, especially when used at high doses or for long periods.
• Kidney Damage: Prolonged use of NSAIDs like Feldene can impair kidney function, leading to fluid retention, high blood pressure, and in severe cases, kidney failure.
• Allergic Reactions: Some individuals may experience allergic reactions to Feldene, ranging from mild skin rashes to severe anaphylaxis, which can be life-threatening.
• Interaction with Other Medications: Feldene may interact with other medications, including blood thinners, certain antidepressants, and diuretics, increasing the risk of side effects or reducing the effectiveness of one or both medications.
• Liver Toxicity: Rarely, NSAIDs like Feldene can cause liver damage, resulting in symptoms such as jaundice, abdominal pain, and nausea.

It’s essential to take Feldene exactly as prescribed by a healthcare professional and to discuss any concerns or potential risks with them before starting treatment. Additionally, regular monitoring of kidney function and other relevant parameters may be necessary for individuals taking Feldene long-term.

Why is this medication prescribed?

Feldene, also known by its generic name piroxicam, is prescribed primarily for its anti-inflammatory and pain-relieving properties. It belongs to a class of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). Here are some common reasons why Feldene may be prescribed:

• Arthritis: Feldene is often prescribed to relieve pain, inflammation, and stiffness associated with various forms of arthritis, including osteoarthritis and rheumatoid arthritis.
• Musculoskeletal Disorders: It may also be used to alleviate pain and inflammation caused by musculoskeletal disorders such as bursitis, tendonitis, and sprains.
• Acute Pain: Feldene can be prescribed for the short-term management of acute pain, such as that caused by injuries or dental procedures.
• Dysmenorrhea: In some cases, Feldene may be used to reduce menstrual pain (dysmenorrhea).

It’s important to note that Feldene is typically prescribed for short-term use to manage acute symptoms or for intermittent use to control chronic conditions. Prolonged or high-dose use of Feldene may increase the risk of adverse effects, such as gastrointestinal complications and cardiovascular events.

How should this medicine be used?

Here’s how Feldene should be used:

• Dosage: The dosage of Feldene varies depending on the condition being treated and the individual’s response to the medication. It’s typically taken once daily, although your doctor may adjust the dosage based on your specific needs.
• Administration: Feldene is usually taken orally, with or without food. It’s essential to follow your doctor’s instructions regarding the timing and frequency of doses.
• Duration: Use Feldene for the shortest duration necessary to relieve your symptoms. Long-term use of NSAIDs, including piroxicam, may increase the risk of serious side effects such as stomach bleeding and kidney problems.
• Interactions: Inform your doctor about all medications, supplements, and herbal products you are taking before starting Feldene, as it may interact with certain drugs.
• Monitoring: Your doctor may recommend regular check-ups to monitor your response to Feldene and assess for any adverse effects.
• Adverse Effects: Watch out for signs of potential side effects, including stomach pain, indigestion, heartburn, nausea, vomiting, diarrhea, constipation, headache, dizziness, and drowsiness. Seek medical attention if you experience severe or persistent symptoms.
• Special Populations: Feldene should be used with caution in older adults, as they may be more sensitive to its effects. It is not recommended for use during pregnancy, particularly in the third trimester, as it may harm the unborn baby. Consult your doctor if you are pregnant or planning to become pregnant while taking Feldene.
• Storage: Store Feldene at room temperature away from moisture and heat. Keep it out of reach of children and pets.

Always consult with your healthcare professional if you have any questions or concerns about how to use Feldene or if you experience any unexpected side effects. They can provide personalized advice based on your medical history and current condition.

Other uses for this medicine

Besides its primary use in treating arthritis-related pain and inflammation, Feldene may also be used off-label for other conditions such as:

• Pain Relief: Feldene may be prescribed for the management of acute pain, including musculoskeletal injuries, dental pain, and postoperative pain.
• Dysmenorrhea: Some individuals may find relief from menstrual cramps with the use of Feldene.
• Migraine: In some cases, Feldene may be used as part of the treatment regimen for migraine headaches.

What special precautions should I follow?

As for special precautions to follow when taking Feldene, here are some important considerations:

• Gastrointestinal Effects: Feldene can increase the risk of gastrointestinal ulcers, bleeding, and other complications. To minimize these risks, take Feldene with food, milk, or an antacid, and avoid alcohol consumption, which can further irritate the stomach lining.
• Cardiovascular Risks: NSAIDs like Feldene may increase the risk of heart attack, stroke, and other cardiovascular events, particularly with long-term use or in individuals with existing cardiovascular disease. Use the lowest effective dose for the shortest duration necessary, especially in patients with heart disease or risk factors for cardiovascular events.
• Kidney Function: Feldene can impair kidney function, especially in individuals with pre-existing kidney disease or those taking other medications that affect the kidneys. Regular monitoring of kidney function may be necessary during treatment with Feldene.
• Allergic Reactions: Seek immediate medical attention if you experience symptoms of an allergic reaction to Feldene, such as rash, itching, swelling, dizziness, or difficulty breathing.
• Interactions: Inform your healthcare provider about all medications, supplements, and herbal products you are taking, as Feldene may interact with certain medications, including blood thinners, ACE inhibitors, and diuretics.
• Pregnancy and Breastfeeding: Avoid using Feldene during late pregnancy, as it may harm the unborn baby. It’s not recommended for use during breastfeeding due to the potential risk of adverse effects in the infant.

Always follow your healthcare provider’s instructions and guidance when taking Feldene or any other medication, and report any concerning symptoms or side effects promptly.

What special dietary instructions should I follow?

Regarding special dietary instructions for Feldene, there are no specific dietary restrictions associated with its use. However, taking Feldene with food, milk, or an antacid can help minimize gastrointestinal side effects. Additionally, maintaining a healthy and balanced diet is generally recommended to support overall health and well-being while taking any medication.

What should I do if I forget a dose?

If you forget to take a dose of Feldene, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you have any concerns or questions about missed doses, consult your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Feldene (piroxicam) can cause various side effects, ranging from mild to severe. It’s essential to be aware of these potential side effects and to seek medical attention if you experience any concerning symptoms. Some common side effects of Feldene include:

• Gastrointestinal Effects: Feldene can irritate the stomach lining and increase the risk of gastrointestinal ulcers, bleeding, and discomfort. Common gastrointestinal side effects may include stomach pain, indigestion, heartburn, nausea, vomiting, diarrhea, or constipation.
• Cardiovascular Effects: NSAIDs like Feldene may increase the risk of heart attack, stroke, and other cardiovascular events, especially with long-term or high-dose use. Symptoms of cardiovascular side effects may include chest pain, shortness of breath, weakness, slurred speech, or sudden numbness or weakness on one side of the body.
• Renal (Kidney) Effects: Prolonged use of Feldene can impair kidney function and lead to kidney damage or failure. Signs of renal side effects may include decreased urination, swelling of the feet or ankles, fatigue, or difficulty breathing.
• Allergic Reactions: Some individuals may experience allergic reactions to Feldene, which can range from mild skin rashes to severe anaphylaxis. Seek immediate medical attention if you develop symptoms such as rash, itching, swelling, dizziness, or difficulty breathing.
• Liver Toxicity: Rarely, NSAIDs like Feldene can cause liver damage, resulting in symptoms such as yellowing of the skin or eyes (jaundice), dark urine, abdominal pain, or nausea.
• Central Nervous System Effects: Feldene may cause central nervous system side effects such as headache, dizziness, drowsiness, or confusion.
• Fluid Retention and Edema: Some individuals may experience fluid retention and swelling (edema) while taking Feldene, particularly in the legs, ankles, or feet.
• Skin Reactions: Feldene may rarely cause skin reactions such as blistering, peeling, or severe rash.
• Blood Disorders: Feldene can affect blood cell production and may lead to anemia (low red blood cell count) or other blood disorders.

It’s important to note that this list is not exhaustive, and other side effects may occur. If you experience any unusual or severe symptoms while taking Feldene, contact your healthcare provider for advice and appropriate management. Additionally, always inform your healthcare provider about all medications, supplements, and herbal products you are taking to minimize the risk of drug interactions and adverse effects.

What should I know about storage and disposal of this medication?

Storage and Disposal:

Storage:

• Store Feldene at room temperature away from moisture and heat.
• Keep Feldene in its original container with the lid tightly closed.
• Do not store Feldene in the bathroom or in damp places.
• Keep Feldene out of reach of children and pets.

Disposal:

• Dispose of unused or expired Feldene properly according to local regulations or guidelines.
• Do not flush Feldene down the toilet or pour it down the drain unless instructed to do so.
• Consult your healthcare provider, pharmacist, or local waste disposal authority for guidance on how to safely dispose of Feldene.

In case of emergency/overdose

In case of emergency or overdose of Feldene, take the following steps:

• Contact emergency medical services (911 in the United States) immediately.
• If possible, provide information about the amount of Feldene ingested and the time it was taken.
• Seek medical attention even if no symptoms are present, as overdose of NSAIDs like Feldene can be serious and require prompt treatment.

What other information should I know?

• Avoid consuming alcohol while taking Feldene, as it may increase the risk of gastrointestinal bleeding and other side effects.
• Feldene may interact with certain medications, including blood thinners, ACE inhibitors, and diuretics. Inform your healthcare provider about all medications, supplements, and herbal products you are taking to avoid potential interactions.
• Feldene should be used with caution in elderly patients, as they may be more susceptible to its side effects, especially gastrointestinal bleeding and kidney impairment.
• Long-term use of Feldene should be avoided whenever possible, as it may increase the risk of adverse effects, including cardiovascular events, gastrointestinal complications, and kidney damage.
• Regular monitoring of kidney function, liver function, and blood pressure may be necessary during treatment with Feldene, especially in patients with pre-existing conditions or risk factors.
• Inform your healthcare provider if you have a history of asthma, allergies, stomach ulcers, liver or kidney disease, heart disease, high blood pressure, or any other medical conditions before starting treatment with Feldene.
• Follow your healthcare provider’s instructions and guidance regarding the use of Feldene, including dosage, duration of treatment, and any special precautions or monitoring requirements.

If you have any questions or concerns about Feldene or its use, consult your healthcare provider or pharmacist for further information and guidance.