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Factive (Generic Gemifloxacin)

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During therapy or for up to many months later, taking gemifloxacin increases your risk of experiencing tendinitis, which is the swelling of a tendon connecting a bone to a muscle, or a tendon rupture, which is the ripping of a tendon. Your shoulder, hand, ankle’s back, or other tendons on your body could be impacted by these issues. Anyone can get tendinitis or experience a tendon rupture, although persons over 60 have the highest risk. Inform your doctor if you currently or ever underwent a kidney, heart, or lung transplant, suffer from kidney disease, have a joint or tendon disorder like rheumatoid arthritis (a disease in which the body attacks its own joints, resulting in pain, swelling, and loss of function), or engage in regular physical activity. Any oral or injectable steroid medication, such as dexamethasone, methylprednisolone (Medrol), or prednisone (Rayos), should be disclosed to your doctor and pharmacist. Gemifloxacin should be stopped right once, along with any of the following tendinitis signs and symptoms, so you can rest and get medical attention: A muscle may experience discomfort, edema, soreness, rigidity, or trouble moving. Stop taking gemifloxacin and seek emergency medical attention if you experience any of the following tendon rupture symptoms: hearing or feeling a snap or pop in a tendon area; bruising following an injury to a tendon area; or being unable to move or bear weight on an affected area.

Gemifloxacin use can result in nerve damage and sensory abnormalities that might persist even after you stop taking moxifloxacin. Immediately after you start taking gemifloxacin, this damage could happen. If you’ve ever experienced peripheral neuropathy, a form of nerve injury that causes tingling, numbness, and pain in the hands and feet, let your doctor know. Call your doctor right away and stop taking gemifloxacin if you have any of the following symptoms: inability to feel light touch, vibrations, pain, heat, or cold; or numbness, tingling, discomfort, burning, or weakness in the arms or legs.

Gemifloxacin use may have negative consequences on the neurological system or brain. Following the initial dose of gemifloxacin, this is possible. Inform your doctor if you currently have or previously had kidney illness, seizures, epilepsy, cerebral arteriosclerosis (narrowing of blood arteries in or around the brain that can cause a stroke or ministroke), stroke, or any other condition. Call your doctor right away and stop taking gemifloxacin if you have any of the following symptoms: seizures, tremors, lightheadedness, dizziness, headaches that won’t go away, trouble getting or keeping asleep, nightmares, a lack of confidence in people, or the impression that people are out to get you; hallucinations (hearing voices or seeing things that are not there); feeling restless, worried, tense, depressed, or confused; memory issues; or other changes in your mood or behavior. Thoughts or acts that could lead to self-harm or suicide.

People who have myasthenia gravis, a neurological system illness that causes muscle weakness, may experience worsening muscle weakness after using gemifloxacin, which could result in serious breathing problems or even death. If you have myasthenia gravis, let your physician know. Your physician might advise against taking gemifloxacin. If you have myasthenia gravis and your doctor advises you to take gemifloxacin, call them right away if you suffer muscle weakness or trouble breathing while taking it.

You should discuss the dangers of taking gemifloxacin with your doctor.

When you start your gemifloxacin treatment, your doctor or pharmacist will give you the manufacturer’s patient information leaflet (Medication Guide). If you have any questions, carefully read the material and contact your doctor or pharmacist. To obtain the Medication Guide, you can also go to the Food and Drug Administration (FDA) website ( or the manufacturer’s website.

Why is this medication prescribed?

Pneumonia is handled by gemifloxacin treatment. Bronchitis may also be treated with gemifloxacin, however this medication shouldn’t be used if there are other options available. The antibiotic gemifloxacin belongs to the fluoroquinolone family. It functions by eradicating the infection-causing germs.

Gemifloxacin is an antibiotic, but it doesn’t treat viral infections like the flu, colds, or other things. Antibiotic overuse raises the likelihood that you’ll get an infection later on that is resistant to antibiotic therapy.

How should this medicine be used?

Gemifloxacin is available as an oral tablet. It is often given once day for 5 or 7 days, with or without food. The sort of infection you have will determine how long your therapy will last. How long to take gemifloxacin will be determined by your physician. Gemifloxacin should be taken every day at roughly the same time. Ask your doctor or pharmacist to explain any instructions on your prescription label that you are unsure about following. Take gemifloxacin as prescribed by your doctor. Never take it in larger or less amounts or more frequently than directed by your doctor.

Never combine gemifloxacin with dairy products like milk, yogurt, or drinks that have added calcium. Gemifloxacin can, however, be taken along with a meal that contains these items.

Do not split, chew, or crush the pills; instead, swallow them whole with a lot of water.

The first few days of your gemifloxacin treatment should see an improvement in your condition. Call your doctor if your symptoms do not disappear or worsen.

Even if you feel better, keep taking the gemifloxacin until the medication is finished. If you suffer any of the significant adverse effects that are detailed in the IMPORTANT WARNING and adverse EFFECTS sections, do not discontinue taking gemifloxacin without first consulting your doctor. It’s possible that your illness won’t be fully treated if you stop taking gemifloxacin too soon or skip doses, and the bacteria might develop antibiotic resistance.

Other uses for this medicine

Ask your doctor or pharmacist for more details if you believe this drug should be used for something else.

What special precautions should I follow?

Before taking gemifloxacin,

  • Inform your doctor and pharmacist if you have ever experienced a severe allergic reaction to any quinolone or fluoroquinolone antibiotic, including ciprofloxacin (Cipro), delafloxacin (Baxdela), levofloxacin (Levaquin), moxifloxacin (Avelox), or ofloxacin, or if you are allergic to any of the ingredients in preparations containing gemifloxacin. For a list of the ingredients, consult the Medication Guide or speak with your pharmacist.
  • Inform your doctor and pharmacist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Mention the drugs in the IMPORTANT WARNING section as well as any of the following: ‘Blood thinners’ or anticoagulants like warfarin (Coumadin, Jantoven); diuretics (often known as “water pills”), erythromycin (E.E.S., Eryc, Erythrocin, and others), certain antidepressants, antipsychotics (medications used to treat mental illness), cisapride (Propulsid), which is unavailable in the United States; hormone replacement therapy, insulin, or other treatments for diabetes such as tolazamide, glimepiride (Amaryl, in Duetact), glipizide (Glucotrol), glyburide (DiaBeta), and tolbutamide; such as amiodarone (Nexterone, Pacerone), procainamide, quinidine (in Nuedexta), and sotalol (Betapace, Betapace AF, Sorine, Sotylize) for irregular heartbeat; NSAIDs, such as ibuprofen (Advil, Motrin, and others), naproxen (Aleve, Naprosyn, and others), or probenecid (Probalan in Col-Probenecid). Your physician will have to adjust the dosage of your drugs or keep a close eye on you for any negative effects.
  • Take gemifloxacin at least 2 hours before or 3 hours after taking any antacids that contain aluminum hydroxide or magnesium hydroxide (Maalox, Mylanta, and other brands); any medications, such as didanosine (Videx) solution; or any vitamin or mineral supplements that contain iron, magnesium, or zinc.
  • Take sucralfate (Carafate) at least two hours after taking gemifloxacin if you’re taking it.
  • Inform your doctor if you or anyone in your family has ever experienced a prolonged QT interval, a rare cardiac condition that can result in erratic heartbeat, fainting, or sudden death. Tell your doctor if you have or have ever had a slow or irregular heartbeat, a heart attack, an aortic aneurysm (swelling of the large artery that transports blood from the heart to the body), high blood pressure, peripheral vascular disease (poor circulation in the blood vessels), Marfan syndrome (a genetic condition that can affect the heart, eyes, blood vessels, and bones), or Ehlers-Danlos syndrome (a genetic condition that can affect skin, joints, or blood vessels).
  • Inform your physician if you are nursing a baby, intend to get pregnant, or are already pregnant. Call your doctor if you become pregnant while taking gemifloxacin.
  • Until you are aware of how this drug affects you, refrain from operating machinery, driving a car, or engaging in other tasks that call for attentiveness or coordination.
  • Plan to prevent exposure to sunlight or UV light (such as that from sunlamps or tanning beds) for an extended period of time, and use protective clothing, sunglasses, and sunscreen. Your skin may become more susceptible to ultraviolet or sunlight if you take gemifloxacin. Call your doctor if your skin begins to become red, swell, or blister, like a severe sunburn.

What special dietary instructions should I follow?

While using gemifloxacin, be careful to consume plenty of water or other fluids every day.

What should I do if I forget a dose?

If you miss a dosage, take it as soon as you recall. If the next dose is soon due, skip the missed one and carry on with your regular dosing plan. Gemifloxacin should only be taken once per day.

What side effects can this medication cause?

Side effects are possible with gemifloxacin. If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Diarrhea
  • Nausea
  • Abdominal pain
  • Vomiting
  • Unusual tiredness

Gemifloxacin should be discontinued and you should call your doctor right away or seek emergency medical attention if you suffer any of the following symptoms or any of the symptoms listed in the IMPORTANT WARNING section:

  • Stomach cramps and severe diarrhea (watery or bloody stools) that might last up to two months or longer after treatment are possible
  • Rash
  • Hives
  • Itching
  • Skin that is flaking or blistering
  • Fever
  • Edema of the lower legs, hands, feet, ankles, throat, lips, tongue, or eyes
  • Throat constriction or hoarseness
  • Breathing or swallowing challenges
  • Persistent or escalating cough
  • Having pale complexion, yellowing skin or eyes, black urine, or light-colored feces
  • Extreme hunger or thirst, pallor, feeling jittery or shaky, a racing or fluttering heartbeat, sweating, frequent urination, trembling, impaired vision, or unusual anxiety
  • Loss of awareness or fainting
  • Unexpected chest, stomach, or back pain

Children who take gemifloxacin may experience complications with their bones, joints, and tissues around their joints. Children under the age of 18 should not get gemifloxacin.

Other negative effects of gemifloxacin are possible. If you experience any strange issues while taking this medicine, contact your doctor right away.

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online at or by phone at 1-800-332-1088 if you have a serious side event.

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. It should not be kept in the bathroom. Store it at room temperature, away from light, excessive heat, and moisture.

As many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilizing a medicine take-back program is the easiest approach to get rid of your medication. To find out about take-back programs in your area, speak with your pharmacist or the garbage/recycling department in your city. If you do not have access to a take-back program, see the FDA’s Safe Disposal of Medicines website at for additional information.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Additionally, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your appointments with your physician and the lab. To monitor your body’s response to gemifloxacin, your doctor could request specific lab tests. Your doctor might advise you to monitor your blood sugar more frequently while taking gemifloxacin if you have diabetes.

No one else should take your medication. It’s likely that your prescription cannot be renewed. Call your doctor if, after stopping the gemifloxacin, you continue to experience signs of infection.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Factive®
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