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Eylea (Generic Aflibercept Injection)

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Why is this medication prescribed?

Eylea (aflibercept) is prescribed primarily for the treatment of various eye conditions, including:

  • Wet age-related macular degeneration (AMD): This condition involves abnormal blood vessel growth under the macula, leading to vision loss. Eylea helps inhibit this abnormal growth, slowing down vision loss and sometimes even improving vision.
  • Diabetic macular edema (DME): DME occurs due to fluid buildup in the macula, leading to vision impairment in people with diabetes. Eylea helps reduce this swelling, improving vision and slowing down vision loss.
  • Macular edema following retinal vein occlusion (RVO): RVO involves blockages in the veins that drain blood from the retina, leading to macular edema and vision loss. Eylea helps reduce the swelling, improving vision and preventing further damage.

In summary, Eylea is prescribed to address conditions that involve abnormal blood vessel growth, fluid buildup, and swelling in the macula, ultimately aiming to preserve or improve vision in affected individuals.

How should this medicine be used?

Eylea is typically administered as an injection directly into the eye by a qualified healthcare professional. The frequency of injections and the duration of treatment will depend on the specific condition being treated and the response of the individual patient.

It’s important to follow your doctor’s instructions carefully regarding the use of Eylea. They will determine the appropriate dosage and treatment schedule based on your condition and individual needs. It’s also crucial to attend all scheduled appointments for injections and follow-up evaluations to monitor your progress and adjust the treatment plan as needed.

Other uses for this medicine

While Eylea (aflibercept) is primarily prescribed for treating eye conditions like wet age-related macular degeneration (AMD), diabetic macular edema (DME), and macular edema following retinal vein occlusion (RVO), it’s essential to note that medications can sometimes be used “off-label” for conditions not specifically approved by regulatory agencies like the FDA. However, off-label use should only be done under the guidance and supervision of a qualified healthcare professional.

What special precautions should I follow?

As for special precautions to follow when using Eylea:

  • Injection Procedure: Eylea is administered via injection into the eye by a healthcare professional. Follow your doctor’s instructions closely regarding the injection procedure and any pre- or post-injection care.
  • Regular Monitoring: Attend all scheduled appointments for injections and follow-up evaluations. Your doctor will monitor your condition and adjust the treatment plan as necessary.
  • Risk of Eye Infection: There is a risk of developing eye infections following the injection procedure. Inform your doctor immediately if you experience any signs of infection such as eye pain, redness, swelling, or discharge.
  • Allergic Reactions: Some individuals may experience allergic reactions to Eylea. Inform your doctor of any allergies you have, especially to medications or ingredients in Eylea, and report any signs of an allergic reaction, such as rash, itching, swelling, dizziness, or difficulty breathing.
  • Pregnancy and Breastfeeding: It’s essential to inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. The safety of Eylea during pregnancy and breastfeeding has not been established, so your doctor will weigh the potential benefits and risks before prescribing Eylea in such situations.
  • Other Medical Conditions: Inform your doctor about any other medical conditions you have, especially if you have a history of blood clots or certain types of eye conditions.

Always consult your healthcare provider for personalized advice and follow their recommendations regarding the use of Eylea and any necessary precautions.

What special dietary instructions should I follow?

Regarding special dietary instructions, there are no specific dietary restrictions associated with Eylea. However, maintaining a healthy diet can support overall eye health, especially for conditions like age-related macular degeneration and diabetic eye disease. Eating a diet rich in fruits, vegetables, and omega-3 fatty acids may be beneficial for eye health.

What should I do if I forget a dose?

If you forget a dose of Eylea, contact your healthcare provider as soon as possible to reschedule your appointment for the missed dose. Do not try to administer the missed dose yourself or attempt to catch up by taking extra doses. It’s essential to follow your doctor’s prescribed treatment schedule to ensure the best outcomes.

What side effects can this medication cause?

Eylea (aflibercept) is generally well-tolerated, but like any medication, it can cause side effects in some people. Common side effects of Eylea injections may include:

  • Eye pain or discomfort
  • Eye redness or irritation
  • Increased tears
  • Floaters in the field of vision
  • Temporary blurred vision
  • Eye itching
  • Increased sensitivity to light

These side effects are usually mild and temporary, resolving on their own within a few days after the injection.

Less common but potentially more serious side effects of Eylea may include:

  • Eye infection (endophthalmitis)
  • Retinal detachment
  • Increased eye pressure (ocular hypertension)
  • Blood clots in the blood vessels of the eye
  • Allergic reactions

If you experience any severe or persistent side effects after receiving Eylea injections, it’s essential to contact your healthcare provider promptly. They can evaluate your symptoms and determine the appropriate course of action.

Additionally, some individuals may be at higher risk of certain side effects based on factors such as their medical history or concurrent medications. Always inform your doctor about any medical conditions you have and any medications or supplements you are taking before starting Eylea treatment. This information will help your doctor monitor you closely for potential side effects and adjust your treatment plan as needed.

What should I know about storage and disposal of this medication?

Storage and disposal of Eylea:

  • Storage: Eylea should be stored in the refrigerator at a temperature between 2°C to 8°C (36°F to 46°F). It should be kept in its original carton to protect it from light. Do not freeze Eylea, and do not use it if it has been frozen.
  • Disposal: Used or expired Eylea vials and supplies should be disposed of properly according to local regulations for hazardous waste disposal. Your healthcare provider or pharmacist can provide guidance on the proper disposal procedure.

In case of emergency/overdose

In the case of an overdose or accidental injection of Eylea, seek emergency medical attention immediately. Symptoms of an overdose are not well-documented, but it’s essential to get medical help promptly if you suspect an overdose.

What other information should I know?

  • Inform your healthcare provider about all medications you are taking, including prescription drugs, over-the-counter medications, vitamins, and supplements.
  • Attend all scheduled appointments for Eylea injections and follow-up evaluations as directed by your doctor.
  • Report any new or worsening eye symptoms to your healthcare provider, as they may indicate a need for adjustments to your treatment plan.
  • Understand that Eylea is typically used as part of a comprehensive treatment plan for eye conditions, which may include other medications, lifestyle modifications, and monitoring of underlying health conditions.
  • Follow your doctor’s instructions regarding proper eye care and any additional recommendations to maintain eye health.
  • Keep Eylea and all medications out of the reach of children and pets.

By following these guidelines for storage, disposal, and handling of Eylea, you can help ensure its safe and effective use as part of your treatment plan for eye conditions.

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