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Exforge HCT (Generic Hydrochlorothiazide)

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Why is this medication prescribed?

For the treatment of high blood pressure, hydrochlorothiazide may be used alone or in conjunction with other drugs. Hydrochlorothiazide is used to treat edoema (fluid retention; extra fluid trapped in bodily tissues) brought on by a variety of illnesses, such as heart, kidney, and liver disease, as well as edoema brought on by the use of specific drugs, such as oestrogen and corticosteroids. Diuretics, also known as “water pills,” include hydrochlorothiazide. It works by encouraging the kidneys to excrete extra salt and water from the body into the urine.

High blood pressure is a common illness that, if left untreated, can harm the kidneys, brain, heart, blood vessels, and other organs. Heart disease, a heart attack, heart failure, a stroke, renal failure, eyesight loss, and other issues may result from damage to these organs. Making lifestyle modifications will help you control your blood pressure in addition to taking medication. These adjustments include quitting smoking, drinking alcohol in moderation, eating a diet low in fat and salt, keeping a healthy weight, and exercising for at least 30 minutes most days.

How should this medicine be used?

The oral forms of hydrochlorothiazide include tablets, capsules, and solutions (liquids). Typically, it is consumed once or twice a day. Hydrochlorothiazide may be taken every day or just on particular days of the week when treating edoema. Ask your doctor or chemist to explain any instructions on your prescription label that you are unsure about following. follow the hydrochlorothiazide directions to the letter. Never take it in larger or less amounts or more frequently than directed by your doctor.

Although not curing high blood pressure, hydrochlorothiazide manages it. If you feel fine, keep taking hydrochlorothiazide. Without consulting your doctor, do not discontinue taking hydrochlorothiazide.

Other uses for this medicine

In addition to treating diabetes insipidus, hydrochlorothiazide may also be used to prevent kidney stones in those with excessive blood calcium levels. Discuss the potential dangers of using this medication for your illness with your doctor.

Ask your doctor or chemist for more details if you’re interested in using this medication for any other conditions.

What special precautions should I follow?

Before taking hydrochlorothiazide,

  • If you have any medicine allergies, including those to penicillin,’sulfa drugs’ or hydrochlorothiazide, let your doctor and chemist know right away.
  • Inform your doctor and chemist about any additional prescription and over-the-counter drugs, vitamins, dietary supplements, and herbal products you are now taking or intend to use. Incorporate any of the following: Secobarbital (Seconal), phenobarbital (Celestone), cortisone (Cortone), budesonide (Entocort), and dexamethasone are all examples of barbiturates (Decadron, Dexpak, Dexasone, others), prednisolone, methylprednisolone (Medrol, Meprolone, various brands), hydrocortisone (Cortef, Hydrocortone), and fludrocortisone (Florinef) (Prelone, others), triamcinolone (Aristocort, Azmacort), and prednisone (Deltasone, Meticorten, Sterapred, among others); insulin and oral diabetic medicines, corticotropin (ACTH, HP, Acthar Gel); medications for high blood pressure or discomfort, lithium (Eskalith, Lithobid), nonsteroidal anti-inflammatory drugs (NSAIDs), including ibuprofen (Advil, Motrin, and others), and naproxen (Aleve, Naprosyn, others). Your physician might need to adjust the dosage of your drugs or keep a close eye on you for side effects.
  • Take cholestyramine or colestipol an hour before or four hours after taking hydrochlorothiazide if you also take either of those medications.
  • In case you have kidney illness, let your doctor know. Your physician might advise against taking hydrochlorothiazide.
  • Inform your doctor if you have or have had had kidney or liver illness, high cholesterol, diabetes, asthma, gout, or systemic lupus erythematosus (SLE), a chronic inflammatory disease.
  • Inform your physician if you are nursing a baby, intend to get pregnant, or are already pregnant. Call your doctor right away if you get pregnant while taking hydrochlorothiazide.
  • Have a plan to limit your time spent in the sun and to use sunscreen, sunglasses, and protective clothes. Your skin may become more susceptible to sunlight and you may get certain types of skin cancer as a result of taking hydrochlorothiazide. During the course of your hydrochlorothiazide therapy, your doctor will examine your skin for skin malignancies. If you see any new skin growths or changes, contact your doctor right away.
  • You should be aware that if you stand up too rapidly from a laying position while taking hydrochlorothiazide, you could have dizziness, lightheadedness, and fainting. When you initially start taking hydrochlorothiazide, this is more typical. Get out of bed gradually, resting your feet on the floor for a few minutes before standing up, to avoid this issue. These negative effects may be exacerbated by alcohol.

What special dietary instructions should I follow?

If your doctor prescribes a low-salt or low-sodium diet, or to eat or drink increased amounts of potassium-rich foods (e.g., bananas, prunes, raisins, and orange juice) in your diet, follow these instructions carefully.

What should I do if I forget a dose?

If you miss a dosage, take it as soon as you recall. If your next dose is approaching, skip the missed one and carry on with your regular dosing regimen. To make up for a missing dose, do not take a second one.

What side effects can this medication cause?

If any of these symptoms are severe or do not go away, let your doctor know right once:

  • Excessive urination
  • Diarrhea
  • Reduced appetite
  • Headache
  • Hair fall

Get emergency medical care if you encounter any of the following symptoms, or call your doctor right away:

  • Symptoms of dehydration and electrolyte imbalance include a dry mouth, thirst, nausea, vomiting, weakness, fatigue, drowsiness, restlessness, confusion, muscle weakness, soreness, or cramps, and a rapid heartbeat.
  • Flaking or blistering skin
  • Hives
  • Rash
  • Itching
  • Breathing or swallowing challenges
  • Infection symptoms such a fever, sore throat, chills, and others
  • Uncommon bruising or bleeding
  • Chronic stomach ache that occasionally radiates to the back
  • Aching or swollen joints
  • Alterations in vision, discomfort in the eye, or eyelids that are swollen or red

You or your doctor can submit a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting programme online or by phone if you have a serious side event (1-800-332-1088).

What should I know about storage and disposal of this medication?

Keep this medication tightly closed in the original container and out of the reach of children. Keep it away from excessive heat and moisture at room temperature (not in the bathroom). The liquid or pills must not freeze.

Although many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and are simple for young children to open, it is crucial to keep all medications out of sight and out of reach of children. Always lock safety caps and promptly stash medication up and away from young children where it is out of their sight and reach to prevent poisoning.

Unused prescriptions must be disposed of carefully to prevent pets, kids, and other people from ingesting them. You should not, however, dispose of this medication in the toilet. Instead, utilising a medicine take-back programme is the easiest approach to get rid of your medication. To find out about take-back programmes in your area, speak with your chemist or the garbage/recycling agency in your city. If you do not have access to a take-back programme, see the FDA’s Safe Disposal of Medications website at for additional information.

In case of emergency/overdose

Call the poison control hotline at 1-800-222-1222 in the event of an overdose. Moreover, information can be found online at Call 911 right once if the person has collapsed, experienced a seizure, is having difficulty breathing, or cannot be roused.

What other information should I know?

Keep all of your appointments with your physician and the lab. Blood tests should be performed occasionally, and your blood pressure should be checked often.

Inform the lab staff and your doctor that you are taking hydrochlorothiazide prior to any laboratory test.

No one else should take your medication. Any queries you may have regarding prescription refills should be directed to your chemist.

You should keep a written record of every medication you take, including any over-the-counter (OTC) items, prescription drugs, and dietary supplements like vitamins and minerals. This list should be brought with you whenever you see a doctor or are admitted to the hospital. You should always have this information with you in case of emergencies.

Brand names

  • Esidrix®
  • Hydrodiuril®
  • Microzide®
  • Oretic®
  • Zide®
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