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Eucrisa (Generic Crisaborole Topical)

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Why is this medication prescribed?

Eucrisa (generic name: crisaborole) is a prescription medication used topically to treat mild to moderate eczema in adults and children who are at least 3 months old.

Eucrisa is a phosphodiesterase 4 (PDE-4) inhibitor, which works by reducing inflammation and relieving itching associated with eczema. It is typically prescribed for individuals with eczema whose symptoms have not responded well to other treatments or who prefer a nonsteroidal option.

How should this medicine be used?

Here’s how Eucrisa ointment is commonly used:

  • Wash your hands before and after applying Eucrisa ointment, unless you are using it to treat the hands.
  • Apply a thin layer of Eucrisa ointment to the affected area(s) of the skin twice daily, or as directed by your healthcare provider.
  • Gently rub the ointment into the skin until it is absorbed.
  • Avoid applying Eucrisa ointment to healthy skin or open wounds.
  • Eucrisa ointment is for external use only. Avoid contact with the eyes, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water.
  • Do not bandage or wrap the treated area unless instructed to do so by your doctor.

As with any medication, it’s important to follow your doctor’s instructions carefully when using Eucrisa ointment and to continue using it for the full prescribed duration, even if your symptoms improve. If your symptoms worsen or do not improve after a few weeks of treatment, consult your healthcare provider. Additionally, inform your doctor of any other medications you are using, as well as any allergies or skin conditions you may have.

Other uses for this medicine

Eucrisa (crisaborole) is primarily used for the treatment of mild to moderate eczema (atopic dermatitis) in adults and children who are at least 3 months old. However, there are no widely recognized alternative uses for Eucrisa beyond its intended purpose of treating eczema.

What special precautions should I follow?

As for special precautions to follow when using Eucrisa:

  • Allergies: Inform your healthcare provider if you are allergic to crisaborole or any other ingredients in Eucrisa. This medication may contain inactive ingredients that can cause allergic reactions or other problems.
  • Skin Irritation: Although Eucrisa is generally well-tolerated, it may cause mild skin irritation or burning sensation at the application site for some individuals, especially during the first few days of use. If irritation persists or worsens, discontinue use and consult your doctor.
  • Avoid Eye Contact: Eucrisa is for external use only. Avoid getting it in your eyes, mouth, or other mucous membranes. If accidental contact occurs, rinse thoroughly with water.
  • Avoid Open Wounds: Do not apply Eucrisa to open wounds or broken skin. It is intended for use on intact skin affected by eczema.
  • Pregnancy and Breastfeeding: If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of using Eucrisa with your doctor. It is not known if Eucrisa can harm an unborn baby or pass into breast milk.
  • Interactions with Other Medications: Inform your healthcare provider about all the medications, vitamins, and herbal supplements you are taking, as Eucrisa may interact with certain medications.
  • Children and Elderly: Eucrisa is generally safe for use in children aged 3 months and older. However, it’s essential to follow your doctor’s guidance regarding its use in pediatric patients. There are no specific precautions for the elderly population beyond those outlined for adults.

Always follow your healthcare provider’s instructions and read the medication guide provided with Eucrisa for comprehensive information on its safe and effective use. If you have any concerns or experience adverse reactions while using Eucrisa, contact your doctor promptly.

What special dietary instructions should I follow?

Regarding special dietary instructions, there are no specific dietary restrictions associated with the use of Eucrisa. However, maintaining good overall nutrition and hydration can support skin health and may complement the treatment of eczema.

What should I do if I forget a dose?

If you forget to apply a dose of Eucrisa, apply it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not apply extra medication to make up for a missed dose. Using too much Eucrisa or using it more often than prescribed can increase the risk of side effects or skin irritation. If you have any concerns or questions about missed doses, consult your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Eucrisa (crisaborole) is generally well-tolerated, but like any medication, it can cause side effects in some individuals. Common side effects associated with the use of Eucrisa may include:

  • Skin Irritation: This is the most common side effect reported with Eucrisa. Some individuals may experience mild to moderate skin irritation, redness, itching, or a burning sensation at the application site. This usually resolves on its own or with continued use, but if irritation persists or worsens, discontinue use and consult your doctor.
  • Hypersensitivity Reactions: In rare cases, some individuals may experience allergic reactions to Eucrisa. Symptoms may include rash, itching, swelling, dizziness, trouble breathing, or severe skin reactions. If you experience any signs of an allergic reaction, discontinue use and seek immediate medical attention.
  • Eye Irritation: Avoid getting Eucrisa in your eyes, as it may cause irritation. If accidental contact occurs, rinse thoroughly with water.
  • Skin Infections: While not a direct side effect of Eucrisa itself, untreated eczema can sometimes lead to skin infections. If you notice signs of infection such as increased redness, warmth, swelling, pain, or pus at the application site, contact your doctor.
  • Other Side Effects: Some individuals may experience other side effects not listed here. If you notice any unusual symptoms or reactions while using Eucrisa, consult your healthcare provider.

It’s essential to discuss any concerns about side effects with your doctor. They can provide guidance on managing side effects and determine whether Eucrisa is the right treatment option for you. If you experience severe or persistent side effects, discontinue use and seek medical attention promptly.

What should I know about storage and disposal of this medication?

Storage and disposal of Eucrisa:


  • Store Eucrisa at room temperature, away from moisture and heat.
  • Keep the medication tightly closed when not in use.
  • Do not freeze Eucrisa.
  • Keep it out of reach of children and pets.


  • Dispose of unused or expired Eucrisa in accordance with local regulations or guidelines.
  • Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Proper disposal helps prevent environmental contamination and protects others from accidental exposure.

In case of emergency/overdose

  • In case of accidental ingestion of Eucrisa, contact your local poison control center (in the United States, you can call 1-800-222-1222) or seek emergency medical attention.
  • If Eucrisa is applied excessively or ingested accidentally, it is unlikely to cause serious harm. However, it’s essential to seek medical advice to assess the situation and receive appropriate guidance.

What other information should I know?

  • Eucrisa is for external use only. Avoid contact with the eyes, mouth, and other mucous membranes.
  • Use Eucrisa as directed by your healthcare provider. Do not apply more or less than prescribed, and do not use it for longer than recommended.
  • Inform your doctor about any skin conditions, allergies, medications, or supplements you are taking before using Eucrisa.
  • Follow your doctor’s instructions for proper application and frequency of use.
  • It may take several weeks of consistent use before seeing improvement in eczema symptoms. Continue using Eucrisa as prescribed, even if symptoms improve.
  • If you experience worsening of symptoms or no improvement after several weeks of treatment, consult your healthcare provider.
  • Keep Eucrisa away from open flames or sources of ignition, as it is flammable.
  • If you have any questions or concerns about Eucrisa or its use, consult your healthcare provider or pharmacist for guidance.

By following these guidelines, you can ensure the safe and effective use of Eucrisa while minimizing risks and potential adverse effects.

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