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Eryzole (Generic Erythromycin and Sulfisoxazole)

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Why is this medication prescribed?

Erythromycin and Sulfisoxazole are antibiotics used to treat various bacterial infections. Combining erythromycin and sulfisoxazole can enhance the spectrum of bacterial coverage and may be prescribed in cases where the causative agent is unknown or when there’s a need for broader antibiotic coverage.

How should this medicine be used?

Dosage and Administration:

  • Dosage and administration of erythromycin and sulfisoxazole combination can vary based on the specific condition being treated, the severity of the infection, patient age, weight, and other factors.
  • It’s important to follow the prescribed dosage and administration instructions provided by the healthcare provider or pharmacist.
  • These medications are typically taken orally with a full glass of water, either with or without food, as directed by the healthcare provider.
  • It’s important to complete the full course of treatment even if symptoms improve before the medication is finished.
  • If you miss a dose, it’s important to take it as soon as possible. However, if it’s almost time for the next dose, skip the missed dose and continue with the regular dosing schedule. Do not double the dose to catch up.

It’s crucial to use antibiotics only as prescribed by a healthcare professional and to not share them with others or use them for conditions for which they have not been prescribed. Additionally, it’s important to be aware of potential side effects and to contact a healthcare provider if any adverse reactions occur.

What special precautions should I follow?

Special precautions for using erythromycin and sulfisoxazole include:

  • Allergies: Inform your healthcare provider if you have any allergies to erythromycin, sulfonamides, or any other medications. Allergic reactions can range from mild rashes to severe reactions requiring immediate medical attention.
  • Pregnancy and breastfeeding: It’s essential to inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. They will weigh the potential risks and benefits of using these medications during pregnancy or breastfeeding.
  • Liver or kidney problems: If you have a history of liver or kidney problems, your healthcare provider may need to adjust your dosage or monitor you more closely while taking erythromycin and sulfisoxazole.
  • Drug interactions: Erythromycin and sulfisoxazole can interact with other medications, including blood thinners, antacids, and certain anticoagulants. It’s crucial to inform your healthcare provider about all the medications, supplements, and herbal products you are currently taking to avoid potentially harmful interactions.
  • Side effects: Be aware of potential side effects such as nausea, vomiting, diarrhea, stomach pain, dizziness, headache, or skin rash. If you experience any severe or persistent side effects, contact your healthcare provider.
  • Resistance: Overuse or inappropriate use of antibiotics can lead to antibiotic resistance, making the medication less effective against bacterial infections. Take the medication exactly as prescribed and complete the full course of treatment, even if you start feeling better before the medication is finished.

Always follow your healthcare provider’s instructions and advice when taking erythromycin and sulfisoxazole or any other medication. If you have any questions or concerns, don’t hesitate to consult your healthcare provider or pharmacist.

What special dietary instructions should I follow?

Special dietary instructions for erythromycin and sulfisoxazole are generally not necessary. However, you should take these medications with a full glass of water, either with or without food, as directed by your healthcare provider. Avoid consuming alcohol while taking these medications, as it may increase the risk of certain side effects and reduce their effectiveness.

What should I do if I forget a dose?

If you forget a dose of erythromycin and sulfisoxazole, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. It’s important to maintain the prescribed dosing schedule to ensure the effectiveness of the medication. If you have any concerns or questions about missed doses, consult your healthcare provider or pharmacist for guidance.

What side effects can this medication cause?

Erythromycin and sulfisoxazole, like all medications, can cause side effects. Not everyone will experience these side effects, and their severity can vary from person to person. Some common side effects of erythromycin and sulfisoxazole may include:

  • Gastrointestinal issues: Nausea, vomiting, diarrhea, abdominal pain, and loss of appetite are common side effects of both medications.
  • Allergic reactions: Some individuals may experience allergic reactions to erythromycin or sulfisoxazole, which can manifest as skin rash, itching, hives, swelling of the face or throat, difficulty breathing, or severe dizziness. Allergic reactions can be severe and require immediate medical attention.
  • Liver toxicity: Rarely, erythromycin and sulfisoxazole can cause liver damage or hepatitis. Symptoms may include yellowing of the skin or eyes (jaundice), dark urine, persistent nausea or vomiting, abdominal pain, or unusual tiredness. If you experience any of these symptoms, seek medical attention promptly.
  • Blood disorders: Erythromycin and sulfisoxazole can sometimes cause changes in blood cell counts, leading to conditions such as anemia, leukopenia (low white blood cell count), or thrombocytopenia (low platelet count). Symptoms may include unusual tiredness, pale skin, easy bruising or bleeding, or frequent infections.
  • Central nervous system effects: Headache, dizziness, or confusion may occur in some individuals taking erythromycin or sulfisoxazole.
  • Skin reactions: Some people may experience photosensitivity (increased sensitivity to sunlight) or skin rash while taking these medications.
  • Kidney problems: In rare cases, erythromycin and sulfisoxazole may cause kidney damage or kidney stones. Symptoms may include changes in urination, lower back pain, or blood in the urine.

It’s important to note that these are not all possible side effects, and some individuals may experience other side effects not listed here. If you experience any unusual or severe symptoms while taking erythromycin or sulfisoxazole, contact your healthcare provider immediately. They can provide guidance on whether you should continue taking the medication and may recommend alternative treatments if necessary.

What should I know about storage and disposal of this medication?

Regarding storage and disposal of erythromycin and sulfisoxazole:


  • Store erythromycin and sulfisoxazole at room temperature away from moisture and heat.
  • Keep the medications in their original packaging and out of reach of children and pets.
  • Follow any specific storage instructions provided by your pharmacist or healthcare provider.


  • Dispose of unused or expired erythromycin and sulfisoxazole properly according to local guidelines or regulations.
  • Do not flush medications down the toilet or pour them down the drain unless instructed to do so.
  • Consult your pharmacist or local waste disposal authority for proper disposal methods, such as medication take-back programs or community drug disposal programs.

In case of emergency/overdose

  • In case of an overdose of erythromycin and sulfisoxazole, seek emergency medical attention or contact a poison control center immediately.
  • Symptoms of overdose may include severe nausea, vomiting, diarrhea, abdominal pain, confusion, dizziness, or fainting.
  • If possible, bring the medication container or packaging to the emergency room to assist healthcare providers in determining the appropriate treatment.

What other information should I know?

  • Keep all appointments with your healthcare provider for monitoring and follow-up while taking erythromycin and sulfisoxazole.
  • Do not share these medications with others, even if they have similar symptoms, as they may not be appropriate or safe for them.
  • Finish the prescribed course of treatment even if you start feeling better before the medication is finished, unless instructed otherwise by your healthcare provider.
  • Inform any other healthcare providers, including dentists and specialists, about all the medications you are taking, including erythromycin and sulfisoxazole, to avoid potential drug interactions.
  • If you have any questions or concerns about your medication or its use, consult your healthcare provider or pharmacist for guidance.

Following these guidelines can help ensure the safe and effective use of erythromycin and sulfisoxazole and minimize the risk of adverse effects or complications.

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